Chromatin-Associated RNAs Regulate Gene Expression and Chromatin Structure [0.03%]
染色质相关RNA调控基因表达和染色质结构
Bingning Xie,Ann Dean
Bingning Xie
Inside the eukaryotic nucleus, various RNAs are associated with chromatin. These include protein-coding pre-mRNA and different types of non-coding RNAs that are referred to as chromatin-associated RNAs (caRNAs). Recent studies have revealed...
XIST Loss Induces Variable Transcriptional Responses Dependent on Cell States [0.03%]
XIST丢失诱发依赖于细胞状态的转录响应变化
Dongning Chen,Ikrame Naciri,Jie Wu et al.
Dongning Chen et al.
Background/Objectives: The X-inactivation specific transcript (XIST) is a long noncoding RNA playing a crucial regulatory role in X chromosome inactivation (XCI)-a transcriptional regulatory process that silences one of the two X chromosome...
Cellular Delivery of Functional AntimiR Conjugated to Bio-Produced Gold Nanoparticles [0.03%]
生物生产的金纳米颗粒偶联抗miR的细胞递送
Parastoo Pourali,Veronika Benson
Parastoo Pourali
Background/Objectives: Bio-produced gold nanoparticles (AuNPs) are effective carriers of short RNAs into specialized mammalian cells. Their potential application is still limited by scarce knowledge on their uptake and intracellular fate. G...
Human-Specific Suppression of Hepatic Fatty Acid Catabolism by RNA-Binding Protein HuR [0.03%]
RNA结合蛋白HuR特异性抑制人肝脏脂肪酸分解代谢作用
Shohei Takaoka,Marcos E Jaso-Vera,Xiangbo Ruan
Shohei Takaoka
RNA-binding proteins (RBPs) play essential roles in all major steps of RNA processing. Genetic studies in human and mouse models support that many RBPs are crucial for maintaining homeostasis in key tissues/organs, but to what extent the fu...
Navigating the Landscape of Exosomal microRNAs: Charting Their Pivotal Role as Biomarkers in Hematological Malignancies [0.03%]
外泌体微小RNA的研究现状及其在血液系统恶性肿瘤生物标志物中的作用展望
Manlio Fazio,Fabio Stagno,Giuseppa Penna et al.
Manlio Fazio et al.
Under physiological and pathological conditions, all cells release extracellular vesicles named exosomes, which act as transporters of lipidic, protein, and genetic material from parent to recipient cells. Neoplastic cells can secrete highe...
Same Fragments, Different Diseases: Analysis of Identical tRNA Fragments Across Diseases Utilizing Functional and Abundance-Based Databases [0.03%]
相同的片段，不同的疾病——利用功能和丰度数据库跨疾病分析相同的tRNA片段
Adesupo Adetowubo,Sathyanarayanan Vaidhyanathan,Andrey Grigoriev
Adesupo Adetowubo
Background/Objectives: Transfer RNA-derived fragments (tRFs) are small non-coding RNAs increasingly implicated in gene regulation and disease, yet their target specificity and disease relevance remain poorly understood. This is an explorato...
Correction: Garmaa et al. A Systematic Review and Meta-Analysis of microRNA Profiling Studies in Chronic Kidney Diseases. Non-Coding RNA 2024, 10, 30 [0.03%]
关于Garmaa等人的系统回顾和荟萃分析：慢性肾脏疾病中微小核糖核酸谱研究的纠正，非编码rna 2024, 10, 30
Gantsetseg Garmaa,Stefania Bunduc,Tamás Kói et al.
Gantsetseg Garmaa et al.
Text Correction [...].
Published Erratum
Non-coding RNA. 2025 Jul 30;11(4):57. DOI:10.3390/ncrna11040057 2025
Partners in Silencing: Decoding the Mammalian Argonaute Interactome [0.03%]
沉默的伙伴：解码哺乳动物Argonaute互作组蛋白质组学研究
Srinaath Narasimhan,Stefan J Erkeland
Srinaath Narasimhan
MicroRNAs (miRNAs) are key post-transcriptional regulators controlling gene expression across several cellular processes, including development, proliferation, and apoptosis. Their biogenesis involves a multi-step pathway, including the pro...
The Role of Non-Coding RNAs in the Regulation of Oncogenic Pathways in Breast and Gynaecological Cancers [0.03%]
非编码RNA在乳腺和妇科肿瘤致癌通路调控中的作用
Ammar Ansari,Aleksandra Szczesnowska,Natalia Haddad et al.
Ammar Ansari et al.
Female cancers such as breast and gynaecological cancers contribute to a significant global health burden and are a leading cause of fatality among women. With current treatment options often limited by resistance to cytotoxic drugs, side e...
Andrea Corsi,Tonia De Simone,Angela Valentino et al.
Andrea Corsi et al.
Background/Objectives: Non-coding microRNA-34a (miR-34a) regulates the expression of key factors involved in several cellular processes, such as differentiation, apoptosis, proliferation, cell cycle, and senescence. Deregulation of the expr...