miRNA and Its Implications in the Treatment Resistance in Breast Cancer-Narrative Review of What Do We Know So Far [0.03%]
微小核糖核酸与乳腺癌治疗抵抗的相关性——迄今为止的叙述性综述
Isabela Anda Komporaly,Adelina Silvana Gheorghe,Lidia Anca Kajanto et al.
Isabela Anda Komporaly et al.
Breast cancer remains a leading cause of cancer-related mortality worldwide, with treatment resistance and tumor heterogeneity posing major clinical challenges. MicroRNAs (miRNAs), small non-coding RNAs regulating gene expression, have emer...
Akari Fukumoto,Moeka Nakashima,Satoru Matsuda
Akari Fukumoto
Food is a crucial component affecting the health of individuals, which may have the potential to expand lifespan. It has been shown that a long lifespan may be related to fine-tuned autophagy. In general, suitable autophagy could play a sig...
Evaluation of Expression and Clinicopathological Relevance of Small Nucleolar RNAs (snoRNAs) in Invasive Breast Cancer [0.03%]
侵袭性乳腺癌中小核仁RNA(snoRNAs)的表达及临床病理意义评估
Luděk Záveský,Eva Jandáková,Vít Weinberger et al.
Luděk Záveský et al.
Background/Objectives: Breast cancer is a leading cause of cancer-related mortality among women worldwide. Small nucleolar RNAs (snoRNAs) represent a class of non-coding RNAs with potential as novel biomarkers applicable to improve diagnost...
El Cheima Mhamedi,Florent Hubé,Suresh K Alahari et al.
El Cheima Mhamedi et al.
The field of non-coding RNA research is advancing at a breathtaking pace, continually uncovering new layers of regulatory complexity and functional diversity [...].
The Chromosome 19 microRNA Cluster Facilitates Cancer Stemness in Hepatocellular Carcinoma [0.03%]
染色体19的微小核糖核酸簇可促进肝细胞癌干细胞样特性
Marian T Underwood,Varsha Devarapalli,Goodwin G Jinesh et al.
Marian T Underwood et al.
Background/Objectives: Hepatocellular carcinoma (HCC) is one of the world's deadliest cancers; however, the mechanisms that contribute to its aggressiveness are poorly understood. In the recent literature, overexpression of the Chromosome 1...
Jessica Kreutz,Tijana Mitić,Andrea Caporali
Jessica Kreutz
The emergence of single-cell sequencing and computational analysis has dramatically improved our understanding of cellular diversity and gene expression dynamics. The rapid advancement of high-throughput omics technologies has led to an exp...
Javier Avalos,Adrián Perera-Bonaño,M Carmen Limón
Javier Avalos
Long noncoding RNAs (lncRNAs) are transcripts generated by polymerase II, therefore subject to 5' capping and 3' polyadenylation, categorized as such when they are at least 200 nt in size and lack coding function. The lncRNAs were initially...
microRNA Biomarkers in Paediatric Infection Diagnostics-Bridging the Gap Between Evidence and Clinical Application: A Scoping Review [0.03%]
儿童感染诊断中微小核糖核酸生物标志物的证据与临床应用缺口：系统综述
Oenone Rodgers,Anna De Beer,Thomas Waterfield
Oenone Rodgers
Background: Distinguishing between bacterial and viral infections in children remains a significant challenge for clinicians. Traditional biomarkers have limited utility, often leading to antibiotic overprescription due t...
Shailendra S Maurya,Sarita Maurya,Sumit K Chaturvedi
Shailendra S Maurya
Acute myeloid leukemia (AML) is a highly heterogeneous disease, with significantly higher incidence and fatality rates in the elderly. Even with recent decades of research progress in AML, the exact etiology of this deadly disease is still ...
Long Non-Coding RNAs in Psoriasis: A Comprehensive Review of Expression Profiles, Mechanistic Insights, Genetic Associations, and Their Clinical Implications [0.03%]
银屑病长链非编码RNA的研究：表达图谱、机制解析、遗传易感及临床意义综述
Judit Danis,Márta Széll
Judit Danis
Psoriasis is a chronic inflammatory skin disorder affecting approximately 2% of the global population, characterized by abnormal keratinocyte proliferation and dysregulated immune responses. This review examines the emerging role of long no...