The Role of microRNA in the Regulation of Differentiation and the Functionality of Osteoblasts, Osteoclasts, and Their Precursors in Osteoporosis [0.03%]
microRNA在骨质疏松中调控成骨细胞、破骨细胞及其前体细胞的分化和功能的作用
Bulat I Yalaev,Elena I Kaletnik,Yulia S Karpova et al.
Bulat I Yalaev et al.
Osteoporosis is a complex disease that is affected by a variety of factors, including genetic and epigenetic influences. While DNA markers for osteoporosis have been identified, they do not fully explain the hereditary basis of the disease....
Circulating MicroRNAs in Patients with Vulvar Squamous Cell Carcinoma and Its Precursors [0.03%]
外阴鳞状细胞癌及其前期病变患者循环的MicroRNA
Julia Rymuza,Angelika Długosz,Kamil Zalewski et al.
Julia Rymuza et al.
Objectives: Vulvar squamous cell carcinoma (VSCC) is a rare gynecologic malignancy, with most cases arising from differentiated vulvar intraepithelial neoplasia (dVIN). Approximately one-third of VSCC cases originate from high-grade squamou...
Cleft Palate Induced by Mycophenolate Mofetil Is Associated with miR-4680-3p and let-7c-5p in Human Palate Cells [0.03%]
霉酚酸酯诱导的腭裂与人腭细胞中的miR-4680-3p和let-7c-5p有关
Hiroki Yoshioka,Hanane Horita,Yosuke Tsukiboshi et al.
Hiroki Yoshioka et al.
Background/Objectives: Cleft palate is a birth defect associated with environmental and genetic factors. Disturbance of microRNAs (miRNAs) and exposure to medicinal agents during pregnancy can cause cleft palate. Although an association bet...
miRNA Library Preparation Optimisation for Low-Concentration and Low-Volume Paediatric Plasma Samples [0.03%]
用于低浓度和低体积儿科血浆样本的miRNA文库准备优化
Oenone Rodgers,Chris Watson,Thomas Waterfield
Oenone Rodgers
Background: Analysing circulating miRNAs in paediatric plasma is challenging due to typically low sample volumes. The QIAseq miRNA UDI Library Kit (Qiagen, Hilden, Germany) was selected as it has a proven track record with a specific protoc...
Differential Expression of miRNAs Between Young-Onset and Late-Onset Indian Colorectal Carcinoma Patients [0.03%]
年轻型和老年型印度结直肠癌患者的miRNA差异表达分析
Sumaiya Moiz,Barsha Saha,Varsha Mondal et al.
Sumaiya Moiz et al.
Reports indicate a worldwide increase in the incidence of Early-Onset Colorectal Carcinoma (EOCRC) (
Long Intergenic Non-Coding RNAs and BRCA1 in Breast Cancer Pathogenesis: Neighboring Companions or Nemeses? [0.03%]
长的非编码RNA和BRCA1在乳腺癌发生中的作用：毗邻伴侣还是敌人？
Olalekan Olatunde Fadebi,Thabiso Victor Miya,Richard Khanyile et al.
Olalekan Olatunde Fadebi et al.
Breast cancer is one of the leading causes of mortality among women, primarily due to its complex molecular landscape and heterogeneous nature. The tendency of breast cancer patients to develop metastases poses significant challenges in cli...
Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells [0.03%]
氟喹啉恩诺沙星的抗HIV-1效果及对CEM-SS细胞中促病毒hsa-miR-132加工的调控作用
Verena Schlösser,Helen Louise Lightfoot,Christine Leemann et al.
Verena Schlösser et al.
Background: Despite tremendous advances in antiretroviral therapy (ART) against HIV-1 infections, no cure or vaccination is available. Therefore, discovering novel therapeutic strategies remains an urgent need. In that se...
Kajetan Kiełbowski,Anna Jędrasiak,Estera Bakinowska et al.
Kajetan Kiełbowski et al.
Psoriasis is a chronic immune-mediated disease with complex pathogenesis. The altered proliferation and differentiation of keratinocytes, together with the activity of dendritic cells and T cells, are crucial drivers of psoriasis progressio...
In Silico Prediction of Maize microRNA as a Xanthine Oxidase Inhibitor: A New Approach to Treating Hyperuricemia Patients [0.03%]
基于计算预测的玉米microRNA作为黄嘌呤氧化酶抑制剂及治疗高尿酸血症患者的新型策略研究
Manas Joshi,Mohd Mabood Khan
Manas Joshi
Introduction: Hyperuricemia is characterized by increased uric acid (UA) in the body. The ability to block xanthine oxidase (XO) is a useful way to check how different bioactive molecules affect hyperuricemia. Previous re...
Plasma Humanin and Non-Coding RNAs as Biomarkers of Endothelial Dysfunction in Rheumatoid Arthritis: A Pilot Study [0.03%]
血浆人因素和非编码RNA作为类风湿关节炎血管内皮功能障碍生物标志物的初步研究
Donatella Coradduzza,Sara Cruciani,Biagio Di Lorenzo et al.
Donatella Coradduzza et al.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder associated with an increased risk of cardiovascular disease (CVD), largely driven by peripheral endothelial dysfunction (ED). Humanin, a mitochondrial-derived peptide, h...