Extracellular Vesicle lncRNAs as Key Biomolecules for Cell-to-Cell Communication and Circulating Cancer Biomarkers [0.03%]
细胞间通讯和循环肿瘤生物标志物的关键分子细胞外囊泡长链非编码RNA
Panagiotis Papoutsoglou,Antonin Morillon
Panagiotis Papoutsoglou
Extracellular vesicles (EVs) are secreted by almost every cell type and are considered carriers of active biomolecules, such as nucleic acids, proteins, and lipids. Their content can be uptaken and released into the cytoplasm of recipient c...
MicroRNA Biogenesis, Gene Regulation Mechanisms, and Availability in Foods [0.03%]
微小核糖核酸的生物生成、基因调控机制及其在食物中的可得性
Amilton S de Mello,Bradley S Ferguson,Erica L Shebs-Maurine et al.
Amilton S de Mello et al.
MicroRNAs (miRNAs) are small, non-coding RNAs that control gene expression by degrading or repressing mRNA translation into proteins. Research recently suggested that food-derived miRNAs are bioavailable and may be absorbed in the gastroint...
Heidi Schwarzenbach
Heidi Schwarzenbach
Epithelial ovarian cancer (EOC) with its high death incidence rate is generally detected at advanced stages. During its progression, EOC often develops peritoneal metastasis aggravating the outcomes of EOC patients. Studies on non-coding RN...
Chahat Suri,Shashikant Swarnkar,Lvks Bhaskar et al.
Chahat Suri et al.
Introduction: Lung cancer remains one of the most prevalent and deadly cancers globally, with high mortality rates largely due to late-stage diagnosis, aggressive progression, and frequent recurrence. Despite advancements...
Back to the Origin: Mechanisms of circRNA-Directed Regulation of Host Genes in Human Disease [0.03%]
回到原点：circRNA调控宿主基因介导人类疾病的机制研究
Haomiao Yuan,Xizhou Liao,Ding Hu et al.
Haomiao Yuan et al.
Circular RNAs (circRNAs) have been shown to be pivotal regulators in various human diseases by participating in gene splicing, acting as microRNA (miRNA) sponges, interacting with RNA-binding proteins (RBPs), and translating into short pept...
Nicole Carabetta,Chiara Siracusa,Isabella Leo et al.
Nicole Carabetta et al.
Cardiomyopathies are the structural and functional disorders of the myocardium. Etiopathogenesis is complex and involves an interplay of genetic, environmental, and lifestyle factors eventually leading to myocardial abnormalities. It is kno...
Circulating miRNAs in the Plasma of Post-COVID-19 Patients with Typical Recovery and Those with Long-COVID Symptoms: Regulation of Immune Response-Associated Pathways [0.03%]
典型康复和长期新冠症状患者血浆中的循环miRNA：与免疫反应相关途径的调节作用
Anna M Timofeeva,Artem O Nikitin,Georgy A Nevinsky
Anna M Timofeeva
Following the acute phase of SARS-CoV-2 infection, certain individuals experience persistent symptoms referred to as long COVID. This study analyzed the patients categorized into three distinct groups: (1) individuals presenting rheumatolog...
The Circulating miR-107 as a Potential Biomarker Up-Regulated in Castration-Resistant Prostate Cancer [0.03%]
循环miR-107作为潜在的生物标志物在去势抵抗性前列腺癌中表达上调
Jonathan Puente-Rivera,David Alejandro De la Rosa Pérez,Stephanie I Nuñez Olvera et al.
Jonathan Puente-Rivera et al.
Prostate cancer (PCa) is a prevalent malignancy in men globally. Current diagnostic methods like PSA testing have limitations, leading to overdiagnosis and unnecessary treatment. Castration-resistant prostate cancer (CRPC) emerges in some p...
MicroRNA Profiling as a Predictive Indicator for Time to First Treatment in Chronic Lymphocytic Leukemia: Insights from the O-CLL1 Prospective Study [0.03%]
来自O-CLL1前瞻性研究的慢性淋巴细胞性白血病一线临床治疗前微小核糖核酸特征谱分析
Ennio Nano,Francesco Reggiani,Adriana Agnese Amaro et al.
Ennio Nano et al.
A "watch and wait" strategy, delaying treatment until active disease manifests, is adopted for most CLL cases; however, prognostic models incorporating biomarkers have shown to be useful to predict treatment requirement. In our prospective ...
Predicting the Effect of miRNA on Gene Regulation to Foster Translational Multi-Omics Research-A Review on the Role of Super-Enhancers [0.03%]
预测miRNA对基因调控的影响以促进转化多组学研究——超级增强子的作用综述
Sarmistha Das,Shesh N Rai
Sarmistha Das
Gene regulation is crucial for cellular function and homeostasis. It involves diverse mechanisms controlling the production of specific gene products and contributing to tissue-specific variations in gene expression. The dysregulation of ge...