Quantifying yeast lipidomics by high-performance thin-layer chromatography (HPTLC) and comparison to mass spectrometry-based shotgun lipidomics [0.03%]
高性能薄层色谱法(HPTLC)定量酵母脂质组学并与基于质谱的枪击脂质组学比较
Thorsten Meyer,Oskar Knittelfelder,Martin Smolnig et al.
Thorsten Meyer et al.
Lipidomic analysis in diverse biological settings has become a frequent tool to increase our understanding of the processes of life. Cellular lipids play important roles not only as being the main components of cellular membranes, but also ...
A cobalt concentration sensitive Btu-like system facilitates cobalamin uptake in Anabaena sp. PCC 7120 [0.03%]
一种类似Btu的系统可促进麻风螺菌PCC 7120对钴胺素的吸收，并且对该系统而言钴的浓度很敏感
Julia Graf,Leonard Fresenborg,Hans-Michael Seitz et al.
Julia Graf et al.
Metal homeostasis is central to all forms of life, as metals are essential micronutrients with toxic effects at elevated levels. Macromolecular machines facilitate metal uptake into the cells and their intracellular level is regulated by mu...
Predictable regulation of survival by intratumoral microbe-immune crosstalk in patients with lung adenocarcinoma [0.03%]
可预测的肿瘤内微生物-免疫相互作用对肺腺癌患者生存率的影响调节
Shuo Shi,Yuwen Chu,Haiyan Liu et al.
Shuo Shi et al.
Intratumoral microbiota can regulate the tumor immune microenvironment (TIME) and mediate tumor prognosis by promoting inflammatory response or inhibiting anti-tumor effects. Recent studies have elucidated the potential role of local tumor ...
Two TonB-dependent outer membrane transporters involved in heme uptake in Anabaena sp. PCC 7120 [0.03%]
蓝藻菌PCC 7120中两种参与血红素吸收的TonB依赖性外膜转运蛋白
Julia Graf,Martin Schöpperle,Rafael Pernil et al.
Julia Graf et al.
Low availability of micronutrients such as iron has enforced the evolution of uptake systems in all kingdoms of life. In Gram-negative bacteria, outer membrane, periplasmatic and plasma membrane localized proteins facilitate the uptake of i...
The last two transmembrane helices in the APC-type FurE transporter act as an intramolecular chaperone essential for concentrative ER-exit [0.03%]
APC型FurE转运蛋白的最后两个跨膜螺旋充当胞内分子伴侣，对浓缩ER出口至关重要
Yiannis Pyrris,Georgia F Papadaki,Emmanuel Mikros et al.
Yiannis Pyrris et al.
FurE is a H+ symporter specific for the cellular uptake of uric acid, allantoin, uracil, and toxic nucleobase analogues in the fungus Aspergillus nidulans. Being member of the NCS1 protein family, FurE is structurally related to the APC-sup...
Extracellular DNA secreted in yeast cultures is metabolism-specific and inhibits cell proliferation [0.03%]
分泌到酵母培养物中的胞外DNA具有代谢特异性并抑制细胞增殖
Elisabetta de Alteriis,Guido Incerti,Fabrizio Cartenì et al.
Elisabetta de Alteriis et al.
Extracellular DNA (exDNA) can be actively released by living cells and different putative functions have been attributed to it. Further, homologous exDNA has been reported to exert species-specific inhibitory effects on several organisms. H...
The Hrk1 kinase is a determinant of acetic acid tolerance in yeast by modulating H+ and K+ homeostasis [0.03%]
HRK1激酶通过调节H+和K+稳态决定酵母乙酸耐受性
Miguel Antunes,Deepika Kale,Hana Sychrová et al.
Miguel Antunes et al.
Acetic acid-induced stress is a common challenge in natural environments and industrial bioprocesses, significantly affecting the growth and metabolic performance of Saccharomyces cerevisiae. The adaptive response and tolerance to this stre...
Biofilm tolerance, resistance and infections increasing threat of public health [0.03%]
生物被膜的耐药性、抗性和感染对公共卫生构成日益严重的威胁
Shanshan Yang,Xinfei Li,Weihe Cang et al.
Shanshan Yang et al.
Microbial biofilms can cause chronic infection. In the clinical setting, the biofilm-related infections usually persist and reoccur; the main reason is the increased antibiotic resistance of biofilms. Traditional antibiotic therapy is not e...
Basal level of ppGpp coordinates Escherichia coli cell heterogeneity and ampicillin resistance and persistence [0.03%]
核苷酸ppGpp的基线水平协调大肠杆菌细胞异质性及氨苄西林抗性和潜伏态形成
Paulina Katarzyna Grucela,Yong Everett Zhang
Paulina Katarzyna Grucela
The universal stringent response alarmone ppGpp (guanosine penta and tetra phosphates) plays a crucial role in various aspects of fundamental cell physiology (e.g., cell growth rate, cell size) and thus bacterial tolerance to and survival o...
Perrine Hervé,Sarah Monic,Frédéric Bringaud et al.
Perrine Hervé et al.
Phospholipases (PLs) and Lysophospholipases (LysoPLs) are a diverse group of esterases responsible for phospholipid or lysophospholipid hydrolysis. They are involved in several biological processes, including lipid catabolism, modulation of...