Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Bioinformatics and the Role of NR6A1 in the Progression of HCC [0.03%]
基于生物信息学的肝细胞癌预后模型的建立及NR6A1基因在肝细胞癌进展中作用的研究
Zhong-Hua Lin,Jie Zhang,Li-Kun Zhuang et al.
Zhong-Hua Lin et al.
Background and aims: Generally acceptable prognostic models for hepatocellular carcinoma (HCC) are not available. This study aimed to establish a prognostic model for HCC by identifying immune-related differentially expre...
Premorbid Steatohepatitis Increases the Seriousness of Dextran Sulfate Sodium-induced Ulcerative Colitis in Mice [0.03%]
肝前性非酒精性脂肪肝病加重DSS诱导的小鼠溃疡性结肠炎病理损伤
Meng-Yu Wang,Zi-Xuan Wang,Lei-Jie Huang et al.
Meng-Yu Wang et al.
Background and aims: The concurrence of nonalcoholic steatohepatitis (NASH) and ulcerative colitis (UC) is increasingly seen in clinical practice, but the underlying mechanisms remain unclear. This study aimed to develop ...
Management Algorithm for Prevention of Mother-to-child Transmission of Hepatitis B Virus (2022) [0.03%]
乙型肝炎病毒母婴传播阻断管理方案（2022年版）
Zhihua Liu,Zhongdan Chen,Fuqiang Cui et al.
Zhihua Liu et al.
The World Health Organization (WHO) has set the goal of eliminating hepatitis as a threat to public health by 2030. Blocking mother-to-child transmission (MTCT) of hepatitis B virus (HBV) is not only the key to eliminating viral hepatitis, ...
Regional and National Trends of Adult Living Donor Liver Transplantation in the United States Over the Last Two Decades [0.03%]
美国成人活体供肝移植的地区和国家趋势——回顾过去20年的数据
Saleh A Alqahtani,Ahmet Gurakar,Hani Tamim et al.
Saleh A Alqahtani et al.
Background and aims: Liver organ shortage remains a major health burden in the US, with more patients being waitlisted than the number of liver transplants (LTs) performed. This study investigated US national and regional...
Regulatory Effect of JAK2/STAT3 on the Immune Function of Endotoxin-tolerant Dendritic Cells and its Involvement in Acute Liver Failure [0.03%]
JAK2/STAT3在内毒素耐受性树突状细胞免疫功能中的调控作用及其在急性肝衰竭中的作用研究
Yukai Chen,Chaochen Hou,Naibin Yang et al.
Yukai Chen et al.
Background and aims: Acute liver failure (ALF) is a potentially fatal clinical syndrome with no effective treatment. This study aimed to explore the role of Janus kinase 2/signal transducer and activator of transcription ...
HBeAg-negative Patients with Chronic Hepatitis B Virus Infection and Normal Alanine Aminotransferase: Wait or Treat? [0.03%]
乙型肝炎e抗原阴性的慢性乙肝患者及其ALT正常的临床意义：等待还是治疗？
Qiuju Sheng,Ning Wang,Chong Zhang et al.
Qiuju Sheng et al.
Alanine aminotransferase (ALT) is a common clinical indicator of liver inflammation. The current Chinese guidelines for the management of chronic hepatitis B (CHB) recommend antiviral treatment for patients with detectable hepatitis B virus...
Burden of Liver Cancer Attributable to Hepatitis B and Alcohol Globally, in China, and for Five Sociodemographic Index Regions from 1990 to 2021: A Population-based Study [0.03%]
1990年至2021年全球、中国及五大社会人口指数区域肝癌的疾病负担：基于人群的研究（归因于乙型肝炎和酒精）
Background and aims: Liver cancer is a digestive system malignancy that poses a significant public health challenge globally. This study aimed to analyze and compare the epidemiological trends of liver cancer attributed t...
Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Hepatitis B: Protocol for a Phase 3 Randomized Trial [0.03%]
针对慢性乙肝相关肝纤维化的海尼啶治疗三期随机对照临床试验方案
Background and aims: Liver fibrosis is a key process in the progression of chronic liver diseases. However, there are currently no drugs specifically designed to treat liver fibrosis. Our Phase 2 trial of hydronidone for ...