Hypertension Associated with the Risk of Extrahepatic Cancers in the Metabolic Dysfunction-associated Steatotic Liver Disease Population: A Multicenter Cross-sectional Study in China [0.03%]
与代谢功能障碍相关肝脂肪变性肝病人群的高血压与全身恶性肿瘤发病风险的相关性:中国多中心横断面研究
Xinyue Zhao,Feng Xue,Shanshan Wang et al.
Xinyue Zhao et al.
Background and aims: Extrahepatic cancers have been recognized as a significant outcome of metabolic dysfunction-associated steatotic liver disease (MASLD), which involves five cardiometabolic risk factors, including hype...
Association of Changes in Portal Insulin with Immunometabolism During and After Hepatitis C Virus Infection [0.03%]
慢性丙型肝炎病毒感染期间和清除后的门静脉胰岛素变化与免疫代谢的关联研究
Matthew G Menkart,Jenna L Oringher,Moumita Chakraborty et al.
Matthew G Menkart et al.
Background and aims: Insulin resistance is a common extrahepatic manifestation of hepatitis C virus (HCV) infection (HCVi), but its mechanism is poorly understood. While systemic insulin resistance is documented, portal i...
Advancements in Understanding the Role of Oxylipins in Liver Injury and Liver Failure [0.03%]
氧脂素在肝损伤和肝衰竭中作用的研究进展
Xiaoling Su,Aidiya Yimamu,Sheng Tu et al.
Xiaoling Su et al.
End-stage liver disease (ESLD) is characterized by a dramatic deterioration of liver function, frequently accompanied by systemic inflammatory storms and multiple organ failures. Central to the onset and progression of ESLD, systemic inflam...
Metabolic Dysfunction-associated Steatotic Liver Disease and Chronic Kidney Disease: From Epidemiology and Pathophysiology to Clinical Prediction and Treatment Options [0.03%]
与代谢失调相关脂肪性肝病和慢性肾脏病:从流行病学和病理生理到临床预测及治疗选择
Jiacheng Liu,Cuiling Ma,Yafan Wang et al.
Jiacheng Liu et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) and chronic kidney disease (CKD) have shown a significant increase in comorbidity on a global scale due to the prevalence of metabolic syndrome. In 2023, a number of academic ...
LDLR+ Monocytic Myeloid-derived Suppressor Cells Attenuate Allograft Rejection in Liver Transplantation [0.03%]
肝移植中LDLR+单核来源的髓系抑制细胞的抗排斥作用
Xin Zhou,Xinqiang Li,Peng Jiang et al.
Xin Zhou et al.
Background and aims: Liver transplant rejection significantly affects patient prognosis. Myeloid-derived suppressor cells (MDSCs), known for their potent immunoregulatory functions, represent a promising target for managi...
Intestinal Candida albicans is Associated with Subclinical Coronary Atherosclerosis in Metabolic Dysfunction-associated Steatotic Liver Disease with Cirrhosis [0.03%]
代谢功能异常相关肝硬化患者中肠源性白色念珠菌与亚临床冠状动脉粥样硬化的关联研究
Nantawat Satthawiwat,Suthida Visedthorn,Pakorn Ruengket et al.
Nantawat Satthawiwat et al.
Background and aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an independent risk factor for cardiovascular disease (CVD). While gut bacteria have been linked to CVD, the role of intestinal fung...
1,5-Anhydroglucitol Aggravates Acute Liver Failure via the PPARα Signaling Pathway [0.03%]
1,5-安德罗葡萄糖醇通过PPARα信号通路恶化急性肝衰竭
Lingjian Zhang,Yaqi Zhang,Yalei Zhao et al.
Lingjian Zhang et al.
Background and aims: Acute liver failure (ALF) is a severe hepatic injury associated with high short-term mortality. Our previous study found that 1,5-anhydroglucitol (1,5AG) levels correlate with clinical outcomes in pat...
Real-world Effectiveness and Safety of Coblopasvir plus Sofosbuvir in the Treatment of Chronic Hepatitis C Infection in Wenzhou, Eastern China: A Multicenter Observational Study [0.03%]
考西磷联合索磷布韦治疗中国东部温州地区慢性丙型肝炎感染的疗效和安全性:一项多中心观察性研究
Li-Min Ruan,Xiao-Cheng Zhang,Xin-Yu Zhang et al.
Li-Min Ruan et al.
Long-term Dynamic Virological Response Patterns and Clinical Outcomes in Hepatitis B Virus-related Cirrhosis: A Real-world 10-year Cohort Study [0.03%]
一项基于真实世界数据的10年队列研究:慢性乙型肝炎病毒相关肝硬化的长期病毒学应答模式及临床结局
Yuwei Wang,Yaxin Li,Yueyang Yu et al.
Yuwei Wang et al.
Background and aims: The long-term clinical outcomes of patients with hepatitis B virus (HBV)-related cirrhosis receiving nucleos(t)ide analog (NA) therapy according to virological response patterns remain inadequately de...
Moana Da Silva Santiago,George Y Wu
Moana Da Silva Santiago