An Unusual Case of Immune Complex-Mediated Membranoproliferative Glomerulonephritis as Renal Manifestation of Idiopathic Hypereosinophilic Syndrome: A Case Report and Literature Review [0.03%]
以膜增生性肾小球肾炎为肾脏表现的特发性高嗜酸性粒细胞综合征一例并文献复习
Michael Cieza-Terrones,José C De La Flor,Christian Requejo et al.
Michael Cieza-Terrones et al.
Background: Idiopathic hypereosinophilic syndrome (IHES) is a disorder characterized by abnormal and persistent peripheral blood hypereosinophilia (eosinophil count ≥ 1.5 × 109/L and ≥10% eosinophils) with duration ≥ ...
Incidence and Outcomes of COVID-19 Vaccine Hypersensitivity Reactions and Success of COVID-19 Vaccine Provocation Tests Post Previous COVID-19 Vaccine Hypersensitivity [0.03%]
新冠疫苗过敏反应的发生率及预后和既往接种新冠疫苗发生过敏反应后的免疫试验的成功性
Adi Kurniawan,Sukamto Koesnoe,Evy Yunihastuti et al.
Adi Kurniawan et al.
Background: The COVID-19 pandemic has led to high mortality rates. There have been reports of hypersensitivity reactions with mild to severe symptoms. The COVID-19 vaccine provocation test is a vaccination protocol for individuals with a hi...
Hiroshi Sakagami
Hiroshi Sakagami
The journal Medicines (ISSN 2305-6320) was launched in 2014 [...].
Marat Syzdykbayev,Maksut Kazymov,Marat Aubakirov et al.
Marat Syzdykbayev et al.
Background: Traumatic brain injury manifests itself in various forms, ranging from mild impairment of consciousness to severe coma and death. Traumatic brain injury remains one of the leading causes of morbidity and mortality. Currently, th...
Human Leucocyte Antigen Genetics in Idiosyncratic Drug-Induced Liver Injury with Evidence Based on the Roussel Uclaf Causality Assessment Method [0.03%]
基于鲁塞尔·乌克拉夫因果关系评估方法的药物性肝损伤人类白细胞抗原遗传学研究
Rolf Teschke,Gaby Danan
Rolf Teschke
The human leucocyte antigen (HLA) allele variability was studied in cohorts of patients with idiosyncratic drug-induced liver injury (iDILI). Some reports showed an association between HLA genetics and iDILI, proposing HLA alleles as a pote...
Improved Outcomes in Eosinophilic Esophagitis with Higher Medication Possession Ratio [0.03%]
更高的药物依从性可改善嗜酸细胞性食管炎的预后
Nathan T Kolasinski,Eric A Pasman,Cade M Nylund et al.
Nathan T Kolasinski et al.
Eosinophilic esophagitis (EoE) disease activity can be caused by treatment non-adherence. Medication possession ratio (MPR) is an established metric of medication adherence. A higher MPR correlates with better outcomes in several chronic di...
Triple Silencing of HSP27, cFLIP, and CLU Genes Promotes the Sensitivity of Doxazosin-Induced Apoptosis in PC-3 Prostate Cancer Cells [0.03%]
HSP27、cFLIP和CLU基因的三重沉默可促进多沙唑嗪诱导的PC-3前列腺癌细胞凋亡敏感性增强
Jeong Man Cho,Sojung Sun,Eunji Im et al.
Jeong Man Cho et al.
Background: This study investigated how the expression of heat shock protein 27 (HSP27), cellular FLICE-like inhibitory protein (cFLIP), and clusterin (CLU) affects the progression of cancer cells and their susceptibility to doxazosin-induc...
ADME Gene-Related Pharmacogenomic Labeling of FDA-Approved Drugs: Comparison with Clinical Pharmacogenetics Implementation Consortium (CPIC) Evidence Levels [0.03%]
美国FDA批准药物的ADME相关药物基因组学标签与临床药物基因组学实施 consortium(CPIC)证据水平比较
Subrata Deb,Robert Hopefl,Anthony Allen Reeves et al.
Subrata Deb et al.
Pharmacogenomics (PGx) can facilitate the transition to patient-specific drug regimens and thus improve their efficacy and reduce toxicity. The aim of this study was to evaluate the overlap of PGx classification for drug absorption, distrib...
Can a Low-Phosphate Diet for Chronic Kidney Disease Treat Cancer? An Interdisciplinary Literature Review [0.03%]
低磷饮食可以治疗癌症吗？一项跨学科文献回顾
Ronald B Brown,Philip Bigelow
Ronald B Brown
Background: Cancer therapeutics have a low success rate in clinical trials. An interdisciplinary approach is needed to translate basic, clinical, and remote fields of research knowledge into novel cancer treatments. Recent research has iden...
Stephanie Trofymenko,Randa Kutob,Amit Algotar
Stephanie Trofymenko
Background: Obesity is linked to chronic diseases in adults and children. Its prevalence continues to grow in the United States, necessitating the need for healthcare provider training and presenting an opportunity for the education of futu...