The impact of extracellular vesicles on spermatozoa: Navigating toward fertilization [0.03%]
精液外泌体影响及其在受精过程中的作用机制探索
Saumya Gunasekara,Qurat Ul Ain Reshi,Getnet Midekessa et al.
Saumya Gunasekara et al.
Reproduction is a complex and highly regulated biological process, underpinned by a range of hormones and unique biological fluids secreted by the reproductive system, including follicular fluid, oviductal fluid, uterine fluid, seminal flui...
Moringa oleifera leaves aqueous extract mitigates nicotine-induced reproductive toxicity in male rats [0.03%]
摩洛哥 Oleifera 叶提取物可缓解尼古丁引起的雄性大鼠生殖毒性
Ahmed Mohamed Ibrahim,Ahmed Emam Dakrory,Amel Ramadan Omar et al.
Ahmed Mohamed Ibrahim et al.
Nicotine, a chemical component included in tobacco, has been demonstrated to influence various facets of spermatogenesis and sperm functionality. Moringa oleifera Lam. (Moringaceae) is used in traditional medicine to treat various ailments,...
Casimiroa edulis extract modulates testosterone levels, testicular enzymes and spermatogenesis disorders in streptozotocin-induced diabetic male rats [0.03%]
卡西米罗亚提取物调节链脲佐菌素诱导的雄性糖尿病大鼠的睾酮水平，睾丸酶和生精障碍
Aya A Mahmoud,Amel Ramadan Omar,Heba Ali Abd El-Rahman
Aya A Mahmoud
Diabetes mellitus is a serious health issue that adversely affects male reproductive function and contributes to the rise in male infertility. This study examined the effectiveness of Casimiroa edulis leaf extract in improving reproductive ...
Testis-specific gene C3ORF22/BC048671 is dispensable for spermiogenesis and male fertility [0.03%]
睾丸特异性基因C3ORF22/BC048671在精子生成和雄性生育力中可有可无
Shiyue Du,Yongfu Liu,Le Wang et al.
Shiyue Du et al.
Testicular tissue displays the most complex transcriptome across all tissues, with over 2000 genes exhibiting testis-enriched expression patterns. However, the functional ambiguity of such genes limits our understanding of spermatogenesis a...
MicroRNA mediated downregulation of HSD17B1 impairs estrone-to-estradiol conversion in polycystic ovarian syndrome [0.03%]
microRNA介导的HSD17B1下调损害多囊卵巢综合征中雌酮向雌二醇的转化
Prajna Bhandary,Prasanna Kumar Shetty,Praveenkumar Shetty et al.
Prajna Bhandary et al.
Polycystic ovary syndrome (PCOS) is a complicated disorder with genetic and epigenetic factors as the potential contributors of disease progression. The major findings of PCOS involves an imbalanced estrogen and androgen. The gene HSD17B1 i...
Protective effect of nicotinamide mononucleotide against soybean isoflavone induced damage in mouse testis [0.03%]
白藜芦醇通过激活SIRT1通路对抗大豆异黄酮诱导的小鼠睾丸损伤保护作用研究
Kaixuan Wang,Haiwei He,Yadan Jin et al.
Kaixuan Wang et al.
Soybean isoflavone (SI) was one type of phytoestrogen that competitively interacts with estrogen in the body, potentially interfering with endocrine balance, spermatogenesis, and the normal function of testicular cells. Nicotinamide mononuc...
Tannic acid protection against oxidative and inflammatory effects of monosodium glutamate on testis: Molecular and biochemical approach [0.03%]
棓酸对抗味精对睾丸氧化和炎症影响的分子及生化方法研究
Sümeyye Çınar Özkan,Emine Toraman
Sümeyye Çınar Özkan
In this study, the toxic effects of monosodium glutamate (MSG), a widely used food additive, on rat testicular tissue were evaluated and the potential protective role of tannic acid (TA), a natural polyphenolic compound, against this toxici...
Exploring critical hub genes and potential drug candidates for PCOS: A systems biology approach [0.03%]
多囊卵巢综合征关键枢纽基因及潜在药物候选物的系统生物学方法研究
Ali Ahmadizad Firouzjaei,Ali Mahmoudi,Natalia Elizova et al.
Ali Ahmadizad Firouzjaei et al.
Polycystic ovarian syndrome (PCOS) is widely recognized as the most common endocrine disorder in women of reproductive age. We aimed to identify PCOS-related genes by searching the Gene Expression Omnibus (GEO) database, and subsequently us...
Mitigating testicular dysfunction: Metformin's role in combating valproic acid-induced damage in rats [0.03%]
二甲双胍缓解丙戊酸所致大鼠睾丸损伤的作用研究
Alzahraa Ahmed Elhemiely,Wessam H Elesawy,Hayat A Abd El Aal et al.
Alzahraa Ahmed Elhemiely et al.
The male reproductive system is significantly affected by valproic acid (VPA), an anti-epileptic medication recognized for its detrimental effects on testicular function. This study evaluates the protective role of metformin, a hypoglycemic...
Metformin-loaded Chitosan nanoparticles alleviate insulin resistance in the polycystic ovarian syndrome rat model through modulation of PI3K/AKT/ GLUT4 in ovarian tissue [0.03%]
载二氯甲基壳聚糖纳米粒通过调节卵巢组织中PI3K/AKT/GLUT4改善多囊卵巢综合征模型大鼠胰岛素抵抗作用研究
Samah Magdy Issa,Eman H Thabet,Abeer E Dief et al.
Samah Magdy Issa et al.
Polycystic ovary syndrome (PCOS) is a common disorder in females characterized by insulin resistance (IR), hyperandrogenemia and anovulation. The etiology of PCOS is unknown. However, disrupted phosphatidylinositol 3-kinase (PI3K) and prote...