The effect of vitamin D on thyroid autoimmunity in euthyroid men with autoimmune thyroiditis and testosterone deficiency [0.03%]
维生素D对甲功正常、自身免疫性甲状腺炎和睾酮缺乏男性的影响
Robert Krysiak,Karolina Kowalcze,Bogusław Okopień
Robert Krysiak
Background: Autoimmune (Hashimoto's thyroiditis) is characterized by a strong female preponderance, which may suggest that sex hormones have an impact on thyroid autoimmunity. The aim of this study was to investigate whet...
Antioxidant status in rabbit aqueous humor after instillation of ascorbyl laurate-based nanostructures [0.03%]
含抗坏血酸单月桂酯纳米结构滴眼液对兔房水抗氧化状态的影响
Natalia Angel Aillegas,Luis Ignacio Tártara,Gabriela Caballero et al.
Natalia Angel Aillegas et al.
Background: The aim of this work was evaluate the antioxidant effect of ascorbyl laurate (ASC12) based nanostructures applied topically to the cornea of ocular normotensive and hypertensive rabbits. The ASC12 was chosen f...
Antioxidant status in rabbit aqueous humor after instillation of ascorbyl laurate-based nanostructures [0.03%]
基于抗坏血酸单月桂酸酯纳米结构的滴眼液对兔房水抗氧化状态的影响
Natalia Angel Aillegas,Luis Ignacio Tártara,Gabriela Caballero et al.
Natalia Angel Aillegas et al.
Background: The aim of this work was evaluate the antioxidant effect of ascorbyl laurate (ASC12) based nanostructures applied topically to the cornea of ocular normotensive and hypertensive rabbits. The ASC12 was chosen f...
Nicotine reverses the enhanced renal vasodilator capacity in endotoxic rats: Role of α7/α4β2 nAChRs and HSP70 [0.03%]
尼古丁逆转内毒素大鼠肾血管舒张能力增强的作用：α7/α4β2烟碱型乙酰胆碱受体和热休克蛋白70的作用
Abdalla M Wedn,Sahar M El-Gowilly,Mahmoud M El-Mas
Abdalla M Wedn
Background: Nicotine alleviates renal inflammation and injury induced by endotoxemia. This study investigated (i) the nicotine modulation of hemodynamic and renal vasodilatory responses to endotoxemia in rats, and (ii) ro...
Nicotine reverses the enhanced renal vasodilator capacity in endotoxic rats: Role of α7/α4β2 nAChRs and HSP70 [0.03%]
尼古丁逆转内毒素大鼠肾血管扩张的增强作用：α7/α4β2nAChRs和HSP70的作用
Abdalla M Wedn,Sahar M El-Gowilly,Mahmoud M El-Mas
Abdalla M Wedn
Background: Nicotine alleviates renal inflammation and injury induced by endotoxemia. This study investigated (i) the nicotine modulation of hemodynamic and renal vasodilatory responses to endotoxemia in rats, and (ii) ro...
Protective role of pirfenidone against experimentally-induced pancreatitis [0.03%]
吡非尼酮对实验性急性胰腺炎的保护作用研究
Dalia H El-Kashef,Ahmed A Shaaban,Dina S El-Agamy
Dalia H El-Kashef
Background: Pirfenidone (PFD) is an orally active antifibrotic agent that has anti-inflammatory activity in diverse animal models. Its effect against acute pancreatitis (AP) has not been elucidated. Hence, the present inv...
Protective role of pirfenidone against experimentally-induced pancreatitis [0.03%]
吡非尼酮对实验性急性胰腺炎的保护作用研究
Dalia H El-Kashef,Ahmed A Shaaban,Dina S El-Agamy
Dalia H El-Kashef
Background: Pirfenidone (PFD) is an orally active antifibrotic agent that has anti-inflammatory activity in diverse animal models. Its effect against acute pancreatitis (AP) has not been elucidated. Hence, the present inv...
Co-treatment with antidepressants and aripiprazole reversed the MK-801-induced some negative symptoms of schizophrenia in rats [0.03%]
抗抑郁药联合阿立哌唑可逆转MK-801诱导的大鼠精神分裂症部分阴性症状
Marta Hereta,Kinga Kamińska,Zofia Rogóż
Marta Hereta
Background: Schizophrenia is a chronic, most devastating psychiatric illness that impairs mental and social functioning. A few clinical reports have suggested that antidepressant drugs are able to augment the activity of ...
Co-treatment with antidepressants and aripiprazole reversed the MK-801-induced some negative symptoms of schizophrenia in rats [0.03%]
氯胺酮所致精神分裂症阴性样症状大鼠模型的抗抑郁药联合阿立哌唑治疗效应研究
Marta Hereta,Kinga Kamińska,Zofia Rogóż
Marta Hereta
Background: Schizophrenia is a chronic, most devastating psychiatric illness that impairs mental and social functioning. A few clinical reports have suggested that antidepressant drugs are able to augment the activity of ...
In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1,3,5-triazine derivatives as Pf-DHFR inhibitor [0.03%]
作为Pf-DHFR抑制剂的噻唑-1,3,5-三嗪衍生物的体内ADMET研究、对接、合成及抗疟活性评价
Supriya Sahu,Surajit Kumar Ghosh,Prashant Gahtori et al.
Supriya Sahu et al.
Background: Plasmodium falciparum dihydrofolate reductase (Pf-DHFR) is an essential enzyme in the folate pathway and is an important target for antimalarial drug discovery. In this study a modern approach has been underta...