Algorithm guided personalized T cell therapy: machine learning unlocks next generation TCR engineered immunotherapy [0.03%]
算法引导的个性化T细胞治疗：机器学习解锁下一代TCR工程免疫疗法
Zahid Rafiq,Tanzeel Bashir,Weiqin Lu et al.
Zahid Rafiq et al.
Niraparib induces hyperglycemia in ovarian cancer patients: a preliminary pilot study [0.03%]
尼拉帕尼可引起卵巢癌患者的高血糖：初步探索性研究
Konrad Lewandowski,Joanna Stanisławiak-Rudowicz,Edyta Szałek et al.
Konrad Lewandowski et al.
Thiazolidine derivative (LPSF/CR-35) modulates the production of IL-17A, IL-10, IL-4, TFN, CCL2 and CXCL8 in PBMC from systemic sclerosis patients [0.03%]
噻唑烷二酮衍生物（LPSF / CR-35）调节系统性硬化症患者PBMC中IL-17A，IL-10，IL-4，TFN，CCL2和CXCL8的产生
Andréa Tavares Dantas,Anderson Rodrigues de Almeida,Marina Ferraz Cordeiro et al.
Andréa Tavares Dantas et al.
Background: Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, fibrosis, and dysregulation of the immune system. The therapeutic options available for SSc have limited efficacy, and there is ...
The HPA axis and kynurenine pathway: exploring the role of stress and neuroinflammation in treatment-resistant depression [0.03%]
HPA轴和犬尿氨酸途径：探究压力和神经炎症在难治性抑郁中的作用
Madhura M Bose,Anusha Govindula,Madhavan Nampoothiri et al.
Madhura M Bose et al.
Treatment-resistant depression (TRD) continues to pose a major challenge in clinical practice, as a large proportion of patients fail to achieve remission despite multiple antidepressant drugs. Growing evidence indicates that dysregulation ...
Novel LC-MS/MS method for measuring methotrexate in high-dose therapy: a comparative study with commercial EMIT and EIA immunoassays [0.03%]
一种新的LC-MS/MS测定大剂量治疗中甲氨蝶呤浓度的方法及其与商业EMIT和EIA免疫测定法的比较研究
Agnieszka Czajkowska,Aleksandra Mikulska,Martyna Poniewierska et al.
Agnieszka Czajkowska et al.
Background: Methotrexate (MTX) is a widely used chemotherapeutic agent in pediatric oncology, where high-dose protocols (HDMTX; ≥500 mg/m2) are standard for treating hematological and central nervous system malignancies....
Correction to: Apoptotic mechanisms of the biotechnologically produced arylnaphtalene lignan justicidin B in the acute myeloid leukemia-derived cell line HL-60 [0.03%]
急性髓系白血病来源的HL-60细胞系中生物技术产生的茋类木脂素justicidin B的促凋亡机制校正文章
Georgi Momekov,Deyan Yossifov,Margarita Guenova et al.
Georgi Momekov et al.
Published Erratum
Pharmacological reports : PR. 2025 Nov 10. DOI:10.1007/s43440-025-00798-3 2025
Εffects of MTR and AS3MT variants on antipsychotic response: prospective evidence from a naturalistic study in Greece [0.03%]
MTR和AS3MT基因变异对抗精神病药物反应的影响：来自希腊一项自然主义研究的证据
Charikleia Ntenti,Magdalini Filippiadou,Domniki Loukaki-Gkountara et al.
Charikleia Ntenti et al.
Background: Schizophrenia and related psychotic disorders represent a major cause of global disability, while patients show wide variability in their response to antipsychotic therapy. Genetic variants in one-carbon metab...
The ketogenic diet in Parkinson's disease: a potential therapeutic strategy [0.03%]
生酮饮食与帕金森病：潜在的治疗策略
Barbara Pokora,Kacper Pokora,Agata Binienda et al.
Barbara Pokora et al.
Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide, characterized by debilitating motor and non-motor symptoms. Its complex pathogenesis involves dopaminergic neuron degeneration, α-synuclein aggregatio...
The application of machine learning in the evaluation of urinary tract infections incidence in patients in a Nursing and Treatment Facility [0.03%]
机器学习在护理康复机构住院患者尿路感染发生率评估中的应用分析
Urszula Grzegorzek,Joanna Sobiak,Ewa Jaworucka et al.
Urszula Grzegorzek et al.
Background: Urinary tract infection (UTI) is a serious problem in the healthcare system. It is caused by bacteria from the gastrointestinal tract. The risk factors that impact the UTI incidence include administration of c...
Agnieszka Łoboda,Tomasz Zieliński,Józef Dulak
Agnieszka Łoboda
Heart regeneration, or the replacement or restoration of damaged myocardium, remains one of the most challenging areas in regenerative medicine, primarily due to the limited regenerative capacity of the adult human heart. Unlike the embryon...