The Sigma1 receptor antagonist CM304 potentiates the antinociceptive effects of the cannabinoid receptor agonist delta9-tetrahydrocannabinol in rats and mice [0.03%]
σ1受体拮抗剂CM304可增强大麻素受体激动剂δ-四氢大麻酚在大鼠和小鼠中的镇痛作用
Elmira Zolali,Mallory Burns,Sebastiano Intagliata et al.
Elmira Zolali et al.
GNE-317 ameliorates neuroinflammation stimulated by lipopolysaccharide via PI3K/Akt/mTOR pathway [0.03%]
GNE-317通过PI3K/Akt/mTOR信号途径改善脂多糖引起的神经炎症反应
Yoojin Lee,Namkwon Kim,Haeun Hwang et al.
Yoojin Lee et al.
Potentiating anti-inflammatory and antioxidant effects in vitro: the combined action of zofenoprilat and nebivolol [0.03%]
体外协同作用:佐芬普利拉联合奈必洛尔的抗炎和抗氧化作用增强效应
Eleonora Maceroni,Annamaria Cimini,Michele dAngelo et al.
Eleonora Maceroni et al.
Background: The present study investigated the combined effects of zofenoprilat (ZOFE) and nebivolol (NEBI) on endothelial function, focusing on their anti-inflammatory and antioxidant properties. The purpose was to evalu...
Diurnal variation of cisplatin-induced anti-tumor effect and renal toxicity in mice bearing human colon cancer cells [0.03%]
顺铂诱导的抗肿瘤效应和肾脏毒性的昼夜变化规律小鼠人源结肠癌细胞移植瘤模型中的研究
Hiroki Yoshioka,Yurie Mikami,Kohei Matsushita et al.
Hiroki Yoshioka et al.
The synaptic triad in depression: how stress-related pathways converge on BDNF, NMDA receptor, and MMP-9 [0.03%]
抑郁症中的突触三联体:应激相关通路如何在BDNF、NMDAR和MMP-9处汇聚
Bartosz Adam Frycz,Magdalena Dutsch-Wicherek,Olga Płaza et al.
Bartosz Adam Frycz et al.
Targeting mitochondrial deubiquitinase USP30 to induce mitophagy in heteroplasmic mitochondrial diseases [0.03%]
靶向线粒体脱泛素酶USP30诱导异质性线粒体疾病的线粒体自噬
Brígida R Pinho,Vasco Martins,Anitta R Chacko et al.
Brígida R Pinho et al.
WIN55,212-2 attenuates intestinal fibrosis in a DSS-induced mouse model [0.03%]
WIN55,212-2减轻DSS诱导的小鼠结肠纤维化
Zofia Misztal,Maria Wołyniak,Ewa Małecka-Wojciesko et al.
Zofia Misztal et al.
Metformin in skin diseases: the role of gut microbiota and immune response [0.03%]
二甲双胍与皮肤病:肠道菌群和免疫反应的作用
Aneta Kiecka,Barbara Macura,Marian Szczepanik
Aneta Kiecka
Impact of environmentally induced hypothermia on fentanyl and norfentanyl pharmacokinetics following intravenous administration to Wistar rats [0.03%]
环境因素诱发的低体温对大鼠静脉注射芬太尼及诺芬太尼药动学的影响
Paulina Stach,Kamil Skowron,Sebastian Rojek et al.
Paulina Stach et al.
Background: Fentanyl, a synthetic opioid with potent analgesic and sedative properties, is widely administered in intensive care. Many critically ill patients present with, or develop, hypothermia driven by multifactorial...
Barbara Pagliarani,Letizia Pruccoli,Chiara Chemello et al.
Barbara Pagliarani et al.