Log-probit accompanied with Tallarida and Chou-Talalay-Martin methods in an isobolographic analysis of interactions between two antiseizure medications - a comparative study [0.03%]
联合应用Tallarida和Chou-Talalay-Martin方法的对数正态等剂量同系图分析两种抗癫痫药物之间的相互作用:一项比较研究
Jarogniew J Łuszczki,Katarzyna Gustaw-Rothenberg,Magdalena Florek-Łuszczki
Jarogniew J Łuszczki
Background: The isobolographic analysis is a gold standard in the assessment of interactions between drugs in experimental studies. Although some isobolographic approaches are available, the most popular methods to charac...
Green tea's secret weapon: a review on the protective effects of epigallocatechin-3-gallate against ischemia/reperfusion damage [0.03%]
绿茶的秘方:表没食子儿茶素-3- gallate对抗缺血/再灌注损伤的保护作用综述
Yingxin Wang,Ying Cao,Yue Zhao
Yingxin Wang
In vitro repositioning therapy with olaparib, temozolomide and oxaliplatin in glioblastoma cell lines: U118, U87, U251, H4 and human fibroblasts [0.03%]
奥拉帕利、替莫唑胺和奥沙利铂体外重新定位治疗胶质母细胞瘤细胞系:U118、U87、U251、H4及人类成纤维细胞
Anna Zając-Grabiec,Anna Czopek,Karolina Pazdan et al.
Anna Zając-Grabiec et al.
Background: Central nervous system (CNS) tumors, including gliomas, are among the most aggressive cancers, with glioblastoma multiforme (GBM) being the most common and lethal. This study explores the potential of multidru...
MIM1 - a selective Mcl-1 protein inhibitor augments the proapoptotic activity of moxifloxacin toward MDA-MB-231 triple-negative breast cancer cells - a preliminary in vitro study [0.03%]
MIM1-mcl-1蛋白的选择性抑制剂增强莫西沙星对三阴性乳腺癌MDA-MB-231细胞的促凋亡活性-初步体外研究
Artur Beberok,Zuzanna Rzepka,Jakub Rok et al.
Artur Beberok et al.
Background: Triple-negative breast cancer (TNBC) is characterized by high invasiveness, high metastatic potential, and poor prognosis. TNBC is not sensitive to endocrine therapy or HER2-targeted treatment, highlighting th...
Epigenetic modulation in cancer drug discovery: promising targets and clinical applications [0.03%]
表观遗传调控在癌症药物发现中的作用:有前景的目标和临床应用
Sundaram Vickram,Shofia Saghya Infant,Manikandan Sivasubramanian et al.
Sundaram Vickram et al.
Epigenetic modulation has emerged as a central strategy that can change the fate of tumour cells to offer more rational and precise approaches by modulating reversible changes in chromatin structure, regulating gene expression without alter...
The xanthine oxidase inhibitor allopurinol prevents thermal and mechanical hyperalgesia in a mouse model of peripheral mononeuropathy [0.03%]
黄嘌呤氧化酶抑制剂alloperurinol可预防外周单神经病鼠模型的热痛和机械痛过敏现象
Aécio C Fagundes,Gisele Hansel,Diogo O Souza et al.
Aécio C Fagundes et al.
Determination of serum concentrations of canrenone (active metabolite of spironolactone) in patients with heart failure with reduced ejection fraction: a cross-sectional study [0.03%]
心力衰竭患者坎利酮(螺内酯活性代谢产物)血药浓度测定:一项横断面研究
Marie Lazarova,Romana Urinovska,Ivana Kacirova et al.
Marie Lazarova et al.
Background: Serum canrenone concentrations have so far only been measured in patients with acute heart failure or heart failure with preserved ejection fraction. The results of these studies showed that low or undetectabl...
Non-invasive pharmacological advances in early retinopathy treatment: bioactive herbal compounds, polymer delivery systems, and computational bioprospecting of functional targets [0.03%]
非侵入性药物在早期视网膜病变治疗中的进展:生物活性草本化合物、聚合物递送系统及功能性靶点的计算生物勘探
Christopher Busayo Olowosoke,Thilini Thrimawithana,Tien Huynh
Christopher Busayo Olowosoke
Anti-vascular endothelial growth factor (anti-VEGF), laser, and vitrectomy therapy are commonly used for the management of vision-threatening posterior eye disease (PED), but non-invasive alternatives have garnered increasing popularity as ...
Molecular mechanisms and therapeutic strategies of GPX4 regulation in acute kidney injury [0.03%]
急性肾损伤中GPX4调控的分子机制及治疗策略研究
Zhidan Shi,Chu Zhang,Tian Xie et al.
Zhidan Shi et al.
Correction: Protective effect and molecular mechanisms of magnolol in ischemic stroke [0.03%]
纠正:Magnolol在缺血性脑卒中的保护效应及其分子机制
Xu Wang,Yukun Xiao,Qiyi Ta et al.
Xu Wang et al.
Published Erratum
Pharmacological reports : PR. 2025 Aug 22. DOI:10.1007/s43440-025-00775-w 2025