Value at Risk long memory volatility models with heavy-tailed distributions for cryptocurrencies [0.03%]
具有厚尾分布的长记忆波动模型的加密货币VaR研究
Stephanie Danielle Subramoney,Knowledge Chinhamu,Retius Chifurira
Stephanie Danielle Subramoney
This paper investigates the volatility dynamics and underlying long memory features of four major cryptocurrencies-Bitcoin, Ethereum, Litecoin, and Ripple-which were selected due to their high liquidity, large trading volumes, and historica...
Mathematical Model of Influenza Infection Suggests JAK-STAT Activity Drives Severe Pathologies in Juvenile Mice [0.03%]
数学模型：jak-信号转导和转录激活蛋白(stat)活性驱动流感病毒感染的幼年小鼠出现严重病理变化
Lauren L Luciani,Lauren M Nichols,Brydie R Huckestein et al.
Lauren L Luciani et al.
Children are uniquely susceptible to severe influenza infection, with one million children experiencing severe life-threatening disease each year. However, there is little evidence that an underdeveloped immune system or differences in vira...
Juan Xie,Kyeong Joo Jung,Carter Allen et al.
Juan Xie et al.
Introduction: The advent of high throughput spatial transcriptomics (HST) has allowed for unprecedented characterization of spatially distinct cell communities within a tissue sample. While a wide range of computational t...
Maya B Mathur,Tyler J VanderWeele
Maya B Mathur
When investigators test multiple outcomes or fit different model specifications to the same dataset, as in multiverse analyses, the resulting test statistics may be correlated. We propose new multiple-testing metrics that compare the observ...
Modeling approaches for assessing device-based measures of energy expenditure in school-based studies of body weight status [0.03%]
用于评估学校研究中体重状态的设备能量消耗测量模型方法
Gilson D Honvoh,Roger S Zoh,Anand Gupta et al.
Gilson D Honvoh et al.
Background: Obesity has become an important threat to children's health, with physical and psychological impacts that extend into adulthood. Limited physical activity and sedentary behavior are associated with increased o...
A brief overview of mathematical modeling of the within-host dynamics of Mycobacterium tuberculosis [0.03%]
结核杆菌体内动力学的数学建模综述
Dipanjan Chakraborty,Saikat Batabyal,Vitaly V Ganusov
Dipanjan Chakraborty
Tuberculosis (TB), a disease caused by bacteria Mycobacterium tuberculosis (Mtb), remains one of the major infectious diseases of humans with 10 million TB cases and 1.5 million deaths due to TB worldwide yearly. Upon exposure of a new host...
Kevin C Lutz,Shuang Jiang,Michael L Neugent et al.
Kevin C Lutz et al.
In the last decade, numerous statistical methods have been developed for analyzing microbiome data generated from high-throughput next-generation sequencing technology. Microbiome data are typically characterized by zero inflation, overdisp...
Chénangnon Frédéric Tovissodé,Bert Baumgaertner
Chénangnon Frédéric Tovissodé
There is a growing interest in the joint modeling of the dynamics of disease and health-related beliefs and attitudes, but coupling mechanisms are yet to be understood. We introduce a model where risk information, which can be delayed, come...
A Scalar Poincaré Map for Anti-phase Bursting in Coupled Inhibitory Neurons With Synaptic Depression [0.03%]
具有突触抑郁的耦合抑制神经元中反相爆发的标量Poincaré映射
Mark Olenik,Conor Houghton
Mark Olenik
Short-term synaptic plasticity is found in many areas of the central nervous system. In the inhibitory half-center central pattern generators involved in locomotion, synaptic depression is believed to act as a burst termination mechanism, a...
Pariksheet Nanda,Denise E Kirschner
Pariksheet Nanda
Mathematical and computational models of biological systems are increasingly complex, typically comprised of hybrid multi-scale methods such as ordinary differential equations, partial differential equations, agent-based and rule-based mode...