Chengyuan Tang,Liyu He,Jing Liu et al.
Chengyuan Tang et al.
Background: Mitochondria play fundamental roles in cellular metabolism, signaling, and viability. Disruption of mitochondria not only leads to dysfunction of the organelles but also activates mechanisms of cell injury and...
Prevalence and Management of Diabetic Nephropathy in Western Countries [0.03%]
西方国家糖尿病肾病的流行现状及管理措施分析
Bancha Satirapoj,Sharon G Adler
Bancha Satirapoj
Background: Diabetic nephropathy (DN) often results in end-stage renal disease, and this is the most common reason for initiation of dialysis in the United States. Complications of diabetes, particularly renal disease, su...
Yasuhiko Tomino,Tomohito Gohda
Yasuhiko Tomino
Background: Diabetic nephropathy (DN), especially type 2 diabetes, is now increasing rapidly worldwide, also in Asian countries, and is one of the major long-term vascular complications. The pathogenesis of DN involves bo...
Ruijie Liu,Kyung Lee,John Cijiang He
Ruijie Liu
Background: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease (ESRD) in the USA and worldwide, contributing to significant morbidity and mortality in diabetic patients. A genetic factor for the...
John Feehally,Jonathan Barratt
John Feehally
Background: IgA nephropathy (IgAN) is the commonest primary glomerulonephritis worldwide and a significant cause of chronic kidney disease and end-stage renal disease. It is widely accepted that genetic factors play a rol...
Li Zhu,Hong Zhang
Li Zhu
Background: IgA nephropathy (IgAN) is the most common type of primary glomerulonephritis worldwide. Highly variable data for disease prevalence and reports of familial clustering suggest the involvement of genetic factors...
Kar Neng Lai,Joseph C K Leung,Sydney C W Tang
Kar Neng Lai
Background: IgA nephropathy (IgAN) is a very common glomerulonephritis worldwide. Nevertheless, treatment options for primary IgAN are still largely based on opinion or weak evidence. There is a lack of large randomized c...
West Meets East [0.03%]
西方与东方相遇
Giuseppe Remuzzi
Giuseppe Remuzzi
Zhi-Hong Liu
Zhi-Hong Liu
Jennifer L Harder,Jeffrey B Hodgin,Matthias Kretzler
Jennifer L Harder
Background: The leading cause of ESRD in the U.S. is diabetic kidney disease (DKD). Despite significant efforts to improve outcomes in DKD, the impact on disease progression has been disappointing. This has prompted clini...