Risk Prediction of Arteriovenous Fistula Dysfunction in Hemodialysis Patients Using Routine Clinical Indicators [0.03%]
基于常规临床指标的维持性血液透析患者动静脉内瘘功能不良风险预测研究
Xiaolu Sui,Weixue Xiong,Qianli Fu et al.
Xiaolu Sui et al.
Introduction: Arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis (HD) patients, yet AVF dysfunction remains a prevalent complication in maintenance HD. The risk factors influencing AVF patency a...
Light chain Cast Nephropathy: The Relationship between Tamm-Horsfall Protein Immunoreactivity and Clinical Pathological Features and Prognosis [0.03%]
轻链 cast 千行病:Tamm-Horsfall 蛋白免疫反应性与临床病理特征和预后的相关性分析
Ming-Yue Wang,Zi-Hao Yong,Shuang Wang et al.
Ming-Yue Wang et al.
Introduction: Light chain cast nephropathy (LCCN) results from the coprecipitation of monoclonal light chains with Tamm-Horsfall protein (THP) within the distal nephron, which forms obstructive casts. Although previous st...
Epirubicin Ameliorates Kidney Fibrosis by Inhibiting B56δ-Mediated Lipid Generation [0.03%]
表皮生长因子通过抑制B56delta介导的脂质生成来改善肾纤维化
Ruofan Chen,Jinxiao Shi,Jie Lan et al.
Ruofan Chen et al.
Introduction: Chronic kidney disease (CKD) presents a significant global health challenge, characterized by increased fibrosis and metabolic disturbances. B56δ, a regulatory B subunit of protein phosphatase 2A (PP2A), is...
Navigating Drug-Related Problems in Hemodialysis Patients across Dual Healthcare Systems: Bridging the Gaps for Optimal Medication Safety [0.03%]
透析患者的药物相关问题:跨越双医保体系,实现最佳用药安全
Shan Lii Ching,Ernieda Hatah,Farida Islahudin et al.
Shan Lii Ching et al.
Introduction: Drug-related problems (DRPs) are common in hemodialysis (HD) patients, but the impact of different healthcare delivery models on DRP prevalence, characteristics, and medication-related outcomes remains under...
Association between Antihistamine Use and Clinical Outcomes in Patients on Maintenance Hemodialysis [0.03%]
抗组胺药使用与维持血液透析患者临床结局之间的关系
Junseok Jeon,Yu Jeong Lim,Bo Yeon Kim et al.
Junseok Jeon et al.
Introduction: H1 antihistamines are frequently used to treat pruritus in patients on dialysis, but their safety remains unclear. This study aimed to evaluate the effects of H1 antihistamine use on outcomes in patients und...
Estimated Glomerular Filtration Rate Slope Predicts Survival and Renal Outcomes in Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis: Development and Validation of a Pathogen-Free Model [0.03%]
髓过氧化物酶抗中性粒细胞胞浆抗体相关性肾小球肾炎患者生存率和肾脏预后的估算肾小球滤过率斜率模型的建立及验证:无病原体模型
Jiahui Wang,Weiwei Kong,Junni Wang et al.
Jiahui Wang et al.
Introduction: This study explores the potential of estimated glomerular filtration rate (eGFR) slope as a noninvasive marker for predicting renal survival and patient survival in myeloperoxidase (MPO)-antineutrophil cytop...
The Impact of Gut Microbiota on Immunoglobulin A Nephropathy through the Mediation of Specific Immune Cells: A Mendelian Randomization Study [0.03%]
肠道菌群通过特定免疫细胞介导对免疫球蛋白A肾病的影响:一项孟德尔随机化研究
Junli Wan,Mei Yang,Qilin Chen et al.
Junli Wan et al.
Introduction: Gut microbiota alterations had been implicated in the pathogenesis of IgA nephropathy (IgAN). However, how did the gut microbiota participated in the onset and development of IgAN was unclear. This study inv...
Combined Effects of Pulmonary Hypertension and Heart Valve Calcification on Cardiovascular Outcomes in Maintenance Hemodialysis Patients: A Risk Stratification Study Using Echocardiography [0.03%]
维持性血液透析患者肺动脉高压和心脏瓣膜钙化对心血管结局的联合影响:一项基于超声心动图的风险分层研究
Xinyi Fu,Chenyu Lei,Anning Xu et al.
Xinyi Fu et al.
Introduction: Cardiovascular disease remains the leading cause of mortality in maintenance hemodialysis (MHD) patients. While both pulmonary hypertension (PH) and heart valve calcification (HVC) are established independen...
Additive Association of ABCG2 rs4148155 and SLC22A12 rs75786299 Polymorphisms with Hyperuricemia, Gout, and Nephrolithiasis: A Hospital-Based, Case-Control Study [0.03%]
ABCG2基因rs4148155和SLC22A12基因rs75786299多态性与高尿酸血症、痛风及泌尿系结石的联合作用:一项基于医院病例对照的研究
Ching-Tsai Lin,I-Chieh Chen,Yen-Ju Chen et al.
Ching-Tsai Lin et al.
Introduction: This study aimed to investigate the interaction between the ABCG2 rs4148155 and SLC22A12 rs75786299 variants and their association with incident gout and nephrolithiasis in the Taiwanese population to better...
Immunoprofiling by CyTOF Uncovers Disease-Defining Peripheral Immune Signatures and Mechanistic Links to Renal Injury in IgA Nephropathy [0.03%]
基于CyTOF的免疫谱分析揭示IgA肾病外周免疫特征及与肾脏损伤的相关机制
Shu Qu,Ting Gan,Jia-Wei He et al.
Shu Qu et al.
Introduction: The immunopathogenesis of IgA nephropathy (IgAN) involves mechanisms beyond B-cell dysregulation, yet the full spectrum and clinical relevance of peripheral immune alterations remain insufficiently defined. ...