Sensing succinate: SUCNR1 as a context-dependent metabolic and cellular signal integrator [0.03%]
感应琥珀酸：SUCNR1 作为环境依赖的代谢和细胞信号整合器
Aenne-Dorothea Liebing,Claudia Stäubert
Aenne-Dorothea Liebing
Succinate (SUC), a central intermediate in the mitochondrial tricarboxylic acid (TCA) cycle, functions not only as a metabolic substrate but also acts as the endogenous ligand for succinate receptor 1 (SUCNR1), a Gi- and Gq protein-coupled ...
Breast milk miRNAs and their potential role in the development of atopy in infants [0.03%]
母乳miRNA及其在婴幼儿特应性疾病发生发展中可能扮演的角色
Adrianna Porębska,Maciej Maj,Aizhan Rakhmetullina et al.
Adrianna Porębska et al.
Human breast milk is a dynamic biological fluid enriched with bioactive components, including extracellular vesicle-derived microRNAs (miRNAs), which have emerged as potential mediators of early immune programming. Growing evidence suggests...
Editorial: Reviews in ARF, the most misunderstood G protein I ever knew: a collection of papers exploring the multifaceted functions of an ancient protein family [0.03%]
述评：被误解的G蛋白家族：从《衰老研究》杂志中搜集的一系列关于一种古老蛋白质族系多种作用的研究论文
Paul A Randazzo,Lorraine Santy,Pei-Wen Chen
Paul A Randazzo
Micronutrient balance and brain function: neuropsychological, metabolic, and clinical interactions [0.03%]
微量营养素平衡与脑功能：神经心理学、代谢和临床相互作用
Valeria López-Sebastiani,Karen V Quiroz-Cornejo,Martha Paola Arellano-Salazar et al.
Valeria López-Sebastiani et al.
Micronutrients, encompassing both vitamins and trace elements, play a central role in brain development, metabolic homeostasis, and cognitive performance from early life through old age. Rather than acting solely as enzyme cofactors or anti...
MicroRNAs and genes regulating responses to hypoxia and inflammation expression levels in blood leukocytes as potential biomarkers of initial oxygen deficiency tolerance [0.03%]
血液白细胞中调节对缺氧和炎症反应的微小核糖核酸和基因表达水平作为初始缺氧耐受性的潜在生物标志物
Maria Kirillova,Dzhuliia Dzhalilova,Margarita Maiak et al.
Maria Kirillova et al.
Introduction: Hypoxia-inducible factors (HIFs) play central roles in evoking responses to hypoxia, and their activities are regulated by numerous molecules, including microRNAs. Organisms typically show differing toleranc...
A prospective observational study of lifestyle behaviors and biomarkers to promote cardiometabolic health in healthcare workers during the COVID-19 pandemic [0.03%]
一项前瞻性观察性研究：在新冠大流行期间，促进医疗工作者心血管元代谢健康的生活方式和生物标志物
Mary S McCarthy,Zachary T Colburn,Laurel H Gillette et al.
Mary S McCarthy et al.
Introduction: Nutrition, physical activity, and sleep deficits contribute to diminished health status in healthcare workers (HCWs). The purpose of this study was to focus attention on HCWs by incorporating precision healt...
Pitfalls of onco-metabolomics: impact of sample integrity on metabolomic investigations in more than 4500 human serum samples from ten different cohorts [0.03%]
肿瘤代谢组学的陷阱：样品完整性对超过4500个人类血清样本的代谢组学研究的影响
Michael Ladurner,Selina Strathmeyer,Tobias Ameismeier et al.
Michael Ladurner et al.
Introduction: Metabolomics such as nuclear magnetic resonance spectroscopy or mass spectrometry (MS) in different body fluids are considered potentially useful diagnostic techniques for various diseases including cancer. ...
Exosome-derived ncRNAs and proteins: inflammation regulatory mechanisms and biomarker potential in spinal cord injury [0.03%]
脊髓损伤中炎性反应调控机制及生物标志物潜能的外泌体衍生ncRNA和蛋白研究
Yongliang Wang,Jian Zhang,Jinsheng Liu et al.
Yongliang Wang et al.
Objective: Exosomes, as key intercellular communication carriers, can deliver non-coding RNAs (ncRNAs) and proteins to regulate inflammatory networks, but the molecular mechanisms underlying their regulation of macrophage...
Editorial: Molecular studies and therapeutic approaches on BRCA-associated cancers [0.03%]
与BRCA相关癌症的分子研究和治疗策略的观点评论文章
Audesh Bhat,Xiaoqiang Wang,Preyesh Stephen
Audesh Bhat
Editorial: In honor of Dr. Bruce Ames: innovations in mutagenesis and DNA repair [0.03%]
致布鲁斯·艾姆斯博士：纪念其在突变和DNA修复领域的创新成果
Cecilia Giulivi,Maret G Traber
Cecilia Giulivi