Maria Zavali,Antonios Georgas,Aggeliki Visvardi Bouga et al.
Maria Zavali et al.
The introduction of cell- and biological-based (CBb) vectors for drug delivery has paved new pathways in cancer therapy, capitalizing on the distinct properties inherent to various microbial systems. In this review, we take a critical look ...
Dysregulation of piRNA biogenesis-associated proteins in cancer: mechanisms, evidence, and translational constraints [0.03%]
癌症中与piRNA生物发生相关蛋白质的失调：机制、证据和转化限制
Siyun Peng,Bo Wei,Xing Li et al.
Siyun Peng et al.
PIWI-interacting RNAs (piRNAs), PIWI proteins, and piRNA biogenesis-associated proteins form a conserved RNA network that protects germline genome integrity and is increasingly linked to cancer biology. Most cancer reviews have emphasized a...
Analysis of peripheral blood T-cell levels for predicting immunotherapy response sensitivity in squamous cell carcinoma of the head and neck [0.03%]
外周血T细胞水平分析在预测头颈部鳞癌免疫治疗反应敏感性中的作用
Nuan Li,Lifei Feng,Gaofei Yin et al.
Nuan Li et al.
Objective: To investigate the correlation between peripheral blood immune cell subsets and pathological response to neoadjuvant therapy in locally advanced head and neck squamous cell carcinoma (HNSCC), and to evaluate th...
Pathophysiological mechanisms of benign prostatic obstruction in men with small prostate volume and the emerging role of ultra-minimally invasive prostatic urethral dilation: a narrative review [0.03%]
小体积前列腺男性的良性前列腺增生梗阻的发病机制及超微创经尿道前列腺扩张术的作用：综述文章
Kun Shen,Dawei Zhang,Leinan Yu
Kun Shen
Background: Lower urinary tract symptoms (LUTS) in men have traditionally been interpreted within a volume-based paradigm, in which benign prostatic enlargement is considered the principal driver of bladder outlet obstruc...
Metabolomic profiling of Ashwagandha (Withania somnifera): linking bioactive compounds to functional therapeutic roles [0.03%]
阿育吠陀草药Ashwagandha（Withania somnifera）的代谢组学分析：生物活性化合物与功能治疗作用之间的关系
Gaurav Tripathi,Vasundhra Bindal,Sanju Yadav et al.
Gaurav Tripathi et al.
Background: Withania somnifera (Ashwagandha) is a widely used medicinal plant known for its neuroprotective, hepatoprotective, fertility-enhancing, and anti-inflammatory properties. Although it has a long history of use i...
Isoprostanes as biomarkers of oxidative stress across human diseases and skin pathologies [0.03%]
异前列腺素作为人类疾病和皮肤病氧化应激生物标志物的研究进展
Aleksandra Okuniewska,Narcyz Knap,Ewa Kulpińska et al.
Aleksandra Okuniewska et al.
Oxidative stress (OS), resulting from an imbalance between reactive oxygen species (ROS) production and antioxidative defenses, is connected with various diseases, including cancer. Isoprostanes (IsoPs), derived from peroxidation of polyuns...
Editorial: Advances in gut microbiota, metabolites and the metabolic disorders [0.03%]
述评：肠道微生物群、代谢产物及代谢紊乱的新进展
Hui Han,Jing Wang,Martine Schroyen et al.
Hui Han et al.
Recent advances in research on high-frequency mutations in the ATP7B gene associated with Wilson disease in the Chinese population: from genetic evolution to precision medicine [0.03%]
近期ATP7B基因高频突变与威尔森病遗传进化及精准医学研究进展在中国人群中的研究进展
Qiaoyu Xuan,Daiping Hua,Lanting Sun et al.
Qiaoyu Xuan et al.
Wilson disease (WD) is a hereditary disorder of copper metabolism caused by mutations in the ATP7B gene; the Chinese population exhibits a unique, high-frequency mutation profile centered on the R778L and P992L mutations. This article provi...
LUHMES-derived 3D organoids as an enhanced platform for modelling dopaminergic neurodegeneration in Parkinson's disease [0.03%]
基于LUHMES的三维类器官在帕金森病多巴胺能神经元退行性疾病建模中的应用
Cameron Keighron,Jose C Casa-Martinez,Serena Barral et al.
Cameron Keighron et al.
Background: Parkinson's disease (PD) research traditionally relies on animal models and two-dimensional (2D) culture models. These models fail to recapitulate the complex cellular architecture and network interactions tha...
Editorial: Molecular perspectives on host-pathogen interactions in immune evasion, viral replication, and pathogenesis [0.03%]
述评·分子视角下的宿主病原相互作用在免疫逃逸、病毒复制和致病性中的作用
Nitin Sharma,Safder S Ganaie,Deepak Kumar et al.
Nitin Sharma et al.