Spinal cord injury-induced overflow incontinence reshapes the activin-follistatin-inhibin axis in mouse bladder and kidney [0.03%]
脊髓损伤引起的尿失禁会重塑小鼠膀胱和肾脏中的活化素- follistatin- 抑制素轴
Yucheng Shen,Shengkai Yang,Hai Zhou et al.
Yucheng Shen et al.
Background: Spinal cord injury is a leading cause of neurogenic bladder and upper urinary tract deterioration, yet the molecular remodeling of epithelial-stromal signaling axes in this context remains incompletely defined...
A network-driven computational framework for identifying FDA-approved drug repurposing across heterogeneous brain cancers [0.03%]
一种网络驱动的计算框架用于识别已获FDA批准的药物再利用以治疗不同类型的脑癌
Om Prakash
Om Prakash
Background: Brain cancers are notorious for their heterogeneity, which complicates therapeutic decisions because of recurrently dysregulated signaling pathways. Cancer system characterizations have allowed the identificat...
Construction of a robust sepsis prognostic classifier based on E3 ubiquitin ligase-related genes [0.03%]
基于E3泛素连接酶相关基因的构建脓毒症预后分类器的研究
Haiyan Xue,Lihe Chen,Xiujuan Zhao et al.
Haiyan Xue et al.
Sepsis is a life-threatening disease with high mortality and one of the leading causes of death worldwide. Although studies have shown that ubiquitylation is closely related to the occurrence and development of sepsis, the prognostic and di...
Heterogeneous regulation of fibroblast growth factor 23 in acute kidney injury, chronic kidney disease, and polycystic kidney disease: mechanisms, diagnostic utility, and clinical implications [0.03%]
急性肾损伤、慢性肾脏病和多囊肾病中成纤维细胞生长因子23的异质性调节：机制、诊断价值及临床意义
Xiaohua Hu,Bo Yang,Haimin Chen et al.
Xiaohua Hu et al.
Fibroblast Growth Factor 23 (FGF23) is a bone-derived hormone regulating phosphate and vitamin D metabolism, now recognized as a dynamic biomarker across acute and chronic kidney disorders. Elevated FGF23 is a hallmark of chronic kidney dis...
Comprehensive first-trimester targeted metabolomics for early prediction and understanding of GDM pathophysiology [0.03%]
全面的早孕目标代谢组学在妊娠糖尿病预测和发病机制理解中的应用
Patrycja Mojsak,Adrian Godlewski,Krzysztof Sołowiej et al.
Patrycja Mojsak et al.
Introduction: Gestational diabetes mellitus (GDM) is among the most common metabolic disorders during pregnancy, and early detection is key to reducing complications for both mother and child. Mass spectrometry-based meta...
Correction: Gasdermin B (GSDMB) in psoriatic patients-a preliminary comprehensive study on human serum, urine and skin [0.03%]
纠正：Gasdermin B（GSDMB）在银屑病患者中的作用——关于人体血清、尿液和皮肤的初步综合研究
Julia Nowowiejska,Anna Baran,Anna Pryczynicz et al.
Julia Nowowiejska et al.
[This corrects the article DOI: 10.3389/fmolb.2024.1382069.]. Keywords: GSDMB; cell migration; gasdermin B; ...
Published Erratum
Frontiers in molecular biosciences. 2026 Feb 16:13:1802468. DOI:10.3389/fmolb.2026.1802468 2026
Untargeted metabolomics reveals immune-metabolic signatures in established cases of rheumatoid arthritis [0.03%]
未靶向代谢组学揭示了类风湿关节炎稳定期患者的免疫代谢标志物
Afshan Masood,Reem Almalki,Abeer Malkawi et al.
Afshan Masood et al.
Introduction: Rheumatoid arthritis (RA) is a complex progressive autoimmune disorder wherein chronic inflammation is tightly coupled to metabolic reprogramming. The known diagnostic markers are not sensitive and specific ...
Nucleolus as a cornerstone linking proliferation and metabolism to cellular responses to stress: involvement of transcription factors MYC and p53 [0.03%]
应激条件下细胞增殖、代谢与核仁介导的细胞反应之间的联系：MYC和p53转录因子的参与作用
Аnastasiia Moraleva,Nadezhda Antipova,Pankrat Pavlov et al.
Аnastasiia Moraleva et al.
The nucleoli are a dynamic membraneless organelles in the nucleus playing a key role in cellular homeostasis. Transcription of rDNA, processing of rRNA, and assembly of the ribosomal subunits occur in nucleoli. Aside from ribosome biogenesi...
The role of exosomes in ankylosing spondylitis: from biological features and functional cargo to clinical applications [0.03%]
外泌体在强直性脊柱炎中的作用：从生物学特性及功能载物到临床应用
Han-Ying Yuan,Jia Xu,You-Yu Zhang et al.
Han-Ying Yuan et al.
Exosomes are small extracellular vesicles secreted by nearly all cell types and widely distributed in body fluids. They not only mediate intercellular material transfer but also play an important role in the regulation of immune pathways. G...
The endothelial plasma membrane lipidome and its remodeling under hyperglycemia: an exploratory study [0.03%]
高糖条件下内皮细胞质膜脂组学及其重塑的探索性研究
Ana Reis,Yahya Sohrabi,Lorena Diaz-Sanchez et al.
Ana Reis et al.
Introduction: At the interface between blood and blood vessels, the endothelial plasma membrane is the first point of contact to external stimuli, triggering the cascade of intracellular events responsible for proper vasc...