Why do they sign but not consult? A study on the effectiveness of China's family doctor contract services from the perspective of patient-doctor interaction [0.03%]
为何只签不约？——基于医患互动的中国家庭医生签约服务有效性研究
Xiangfei Li,Yuxin Shi,Xin Li
Xiangfei Li
Background: Family doctor contract services (FDCS) in China aim to promote primary care first-contact, yet the "sign but no consult" phenomenon persists Traditional accessibility models fail to explain the heterogeneity i...
From emergence to amplification: an analysis of lifecycle models to address health mis-disinformation in the digital environment [0.03%]
从出现到放大：数字环境中应对健康错误信息生命周期模型的分析
Ben Sheppard,Linda Durnell,Amy J Haufler
Ben Sheppard
Health misinformation and disinformation (mis-disinformation) on social media presents a growing threat to individual and population health, societal resilience, and national security. While social media enables the rapid dissemination of h...
Post-MI: unsupervised brain tissue segmentation via post-maximized mutual information [0.03%]
基于后最大化互信息的MI分割方法
Ke Niu,Jiadong Guo,Ming Zhang et al.
Ke Niu et al.
Introduction: Brain tissue segmentation in magnetic resonance imaging (MRI) is a fundamental step in quantitative neuroimaging and supports the analysis of structural brain alterations associated with aging. However, voxe...
Beyond chronological age: a decision tree model integrating nutritional and renal function indicators for risk prediction in pre-frail older adults with hepatolithiasis [0.03%]
超越年龄：用于预测肝石病伴发虚弱老年人风险的营养和肾功能指标集成决策树模型
Yi Qin,Feiyuan Zeng,Rilian Ou et al.
Yi Qin et al.
Objectives: This study develops a decision tree model to predict risks and identify key factors in pre-frail older adults hepatolithiasis patients and performance of models. ...
Cerebrospinal fluid opening pressure in relation to symptomatology and craniocervical anatomy in patients with myalgic encephalomyelitis/chronic fatigue syndrome [0.03%]
肌痛性脑脊髓炎/慢性疲劳综合征患者的脑脊液开压与症状及颅颈解剖的关系研究
C Jolley,B Bragée,L Soinne et al.
C Jolley et al.
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease that affects millions worldwide. Its cause remains unknown, although many physiological mechanisms are impaired. Structural...
Redistribution of peripheral blood immune cell subsets and remodeling of intercellular communication in rare Behçet's disease: a single-cell transcriptomics study [0.03%]
罕见白塞病外周血免疫细胞亚群的重新分布及细胞间通讯重塑：单细胞转录组学研究
Yanfei Yang,Yuexin Chen
Yanfei Yang
Background: Behçet's disease (BD) is a rare chronic systemic vasculitis of unknown etiology. The heterogeneity of peripheral blood immune cells and the dysregulation of intercellular communication in BD remain insufficie...
Resolution of systemic inflammation in psoriasis following herring roe oil treatment: a post hoc analysis on inflammatory biomarkers in non-severe psoriatic patients [0.03%]
鲑鱼卵油治疗银屑病患者后的全身性炎症缓解：对非重症银屑病患者炎症生物标志物的事后分析
Thomas A Ringheim-Bakka,Runhild Gammelsaeter,Kåre Steinar Tveit
Thomas A Ringheim-Bakka
Background: Psoriasis is a chronic immune-mediated inflammatory disease (IMID) with systemic involvement. In mild-to-moderate disease, circulating cytokines may inadequately capture systemic inflammatory burden. Composite...
Comparative analysis of candidate gene expression in Asian atopic dermatitis and psoriasis: identification of shared and distinct molecular features [0.03%]
亚洲特应性皮炎和银屑病候选基因表达的比较分析：共同分子特征与独特分子特征的识别
Hye Li Kim,Dong Eun Kim,KeLun Zhang et al.
Hye Li Kim et al.
Background: Atopic dermatitis (AD) and psoriasis are chronic inflammatory skin diseases with distinct molecular profiles, but their clinical differentiation in Asian patients is often difficult due to overlapping or atypi...
Prospective validation protocol for artificial intelligence-assisted standardization of Coma Recovery Scale-Revised scores using electroencephalography and clinical data in disorders of consciousness [0.03%]
基于脑电图和临床数据的昏迷恢复量表修订版人工智能辅助标准化评分前瞻性验证方案
Chuangan Zhou,Yuzhu Gao,Jinqiu Shan et al.
Chuangan Zhou et al.
Background: Disorders of consciousness (DoC) after severe acquired brain injury are difficult to diagnose at the bedside. The Coma Recovery Scale-Revised (CRS-R) is the behavioral reference standard, but raw scores can be...
Breaking tolerance in the glomerulus: complement as a driver and therapeutic target in IgA nephropathy [0.03%]
补体在IgA肾病中的驱动作用及治疗靶点：打破肾小球的耐受状态
Chien-Lin Lu,Chung-Chi Yang,Chia-Chao Wu et al.
Chien-Lin Lu et al.
IgA nephropathy (IgAN) is an established autoimmune glomerular disease driven by mucosal tolerance failure, aberrant IgA1 glycosylation, and anti-glycan autoantibody formation. Mesangial deposition of galactose-deficient IgA1 (Gd-IgA1) comp...