Central neural circuits and their associated mechanisms of inter-organ crosstalk [0.03%]
中枢神经通路及器官互作的分子机制研究进展
Lerui Kang,Jasmine Lu Salas-Hernandez,Ruoshi Xu
Lerui Kang
The central nervous system (CNS), which comprises the brain and spinal cord, serves as the core regulatory hub for maintaining homeostasis and coordinating diverse physiological functions. These functions include interoception, cognition, a...
Dual regulation of autophagy: paradoxical effects on tumor angiogenesis [0.03%]
自噬的双重调控：对肿瘤血管生成的矛盾效应
Shanshan Xiang,Xue Gong,Jiangyuan Zhou et al.
Shanshan Xiang et al.
Autophagy plays a critical role in dynamic cell growth under different environmental conditions and maintains cellular homeostasis and cell viability in response to different cellular injuries, especially in tumor angiogenesis, where there ...
Dual modes of action: direct regulation and ceRNA-mediated mechanisms of ncRNAs in dermal fibroblast senescence [0.03%]
双重作用模式：ncRNA在真皮成纤维细胞衰老过程中的直接调控和ceRNA介导的机制
Juanlie Luo,Jiabao Ma,Hui Tian et al.
Juanlie Luo et al.
Skin aging is characterized by progressive decline in dermal fibroblast function, marked by reduced extracellular matrix (ECM) synthesis, accelerated ECM degradation, diminished repair capacity, and activation of the senescence-associated s...
Advances in porcine stem cell research and their applications in agriculture [0.03%]
猪干细胞研究进展及其农业应用展望
Yangli Pei,Rong Zhou
Yangli Pei
Porcine stem cell research has advanced considerably over the past decade, driven by the dual promise of biomedical modeling and agricultural innovation. This review provides a comprehensive synthesis of recent progress in the isolation, ch...
Research progress on functionalized stem cell therapy strategies in wound healing [0.03%]
功能化干细胞治疗伤口愈合的研究进展
Ting Ye,Weihu Zhang,Nanjian Xu et al.
Ting Ye et al.
The repair of skin injuries, particularly in cases of refractory wounds such as diabetic foot ulcers and severe burns, remains a major clinical challenge. Conventional approaches, including debridement and skin grafting, often fall short of...
Ammonia metabolic reprogramming in the tumor microenvironment: emergence of an immunosuppressive niche [0.03%]
肿瘤微环境中的氨代谢重编程：免疫抑制生态位的出现
Zihao Ye,Hao Wu,Zhanhao Li et al.
Zihao Ye et al.
Metabolic reprogramming within the tumor microenvironment plays a pivotal role in tumor proliferation, progression, and immune evasion. Cancer cells exhibit altered lipid, glucose, and amino acid metabolism to adapt to hostile conditions su...
DEHP induces stress urinary incontinence by causing urethral sphincter dysfunction via inflammation and apoptosis: a mechanism study based on animal experiments, network toxicology, and molecular docking [0.03%]
DEHP所致尿道括约肌炎性损伤和凋亡诱导应激性尿失禁的机制研究
Xiaozhi Xia,Tao Liu,Wei Wang et al.
Xiaozhi Xia et al.
Objective: Di (2-ethylhexyl) phthalate (DEHP), a pervasive environmental pollutant, poses significant health risks, yet its role in stress urinary incontinence (SUI) remains largely unexplored. ...
SLC27, solute carrier 27 family, a long-chain fatty acid membrane transporters, in human cancers [0.03%]
人类肿瘤中长链脂肪酸膜转运蛋白SLC27家族的研究进展及其临床意义
Zhonghang Xu,Jianshi Du,Wen G Jiang et al.
Zhonghang Xu et al.
The Solute Carrier family 27 (SLC27), also known as the fatty acid transport proteins (FATPs) is a group of transmembrane integral proteins that facilitate the entry of long-chain and very long-chain fatty acids into cells. The human SLC27 ...
Correction: AI dialogues in cartilage repair: which guides evidence-based decisions better? [0.03%]
纠正：AI在软骨修复中的对话：哪个更好地指导基于证据的决策？
Senyang Xiao,Hui Li,Dan Xing et al.
Senyang Xiao et al.
[This corrects the article DOI: 10.3389/fcell.2026.1768270.]. Keywords: ChatGPT; cartilage surgery; cartilag...
MBNL1-dependent alternative splicing promotes neuronal differentiation through regulation of NUMA1 exon 16 during fibroblast-to-neuron reprogramming [0.03%]
MBNL1通过调节NUMA1第16外显子在成纤维细胞重编程为神经元过程中促进神经元分化依赖的可变剪接
Jun Li,Qiu-Shuang Long,Ruo-Qi Zhang et al.
Jun Li et al.
Introduction: Direct neuronal reprogramming enables the generation of neurons from somatic cells without passing through a pluripotent state, yet the post-transcriptional mechanisms that refine neuronal identity after fat...