Mechanical forces orchestrate the epigenetic landscape of oral mesenchymal stem/progenitor cell fate in dental and periodontal tissues [0.03%]
Yikun Zhou,Gengming Zhang,Hong He
Yikun Zhou
The oral cavity serves as the primary source of oral mesenchymal stem/progenitor cell populations residing in the dental pulp, periodontal ligament, deciduous tooth pulp, and gingival connective tissue. Oral and periodontal tissues exist in...
Implantation of autogenic and decellularized xenogenic grafts for tissue repair in experiment [0.03%]
Alexander V Pechersky,Viktor I Pechersky,Ilya A Barsuk et al.
Alexander V Pechersky et al.
Introduction: With extensive tissue damage, the body is unable to restore their integrity on its own. Implantation of autogenic and decellularized xenogenic grafts opens up new possibilities for regeneration of damaged co...
Experimental study of platelet-rich fibrin affecting the healing of seawater-impregnated wounds in rabbits [0.03%]
Ke Xie,Zeyu Dai,Daiqing Chen et al.
Ke Xie et al.
Background: To investigate the effect of platelet-rich-fibrin (PRF) on the healing of seawater-impregnated wounds in rabbits and to explore the mechanism. ...
Qiang-Qiang Zhao,Feihong Che,Weiwen Liu et al.
Qiang-Qiang Zhao et al.
Cartilage damage has long been a challenge in regenerative medicine research, due to the avascular nature of cartilage tissue and its intrinsically limited reparative capacity. In recent years, more and more studies have found that the regu...
AC005034.3/hsa-miR-126-5p/EIF3H axis: bioinformatics analysis, expression validation, and association with prognosis and immunosuppressive microenvironment in pancreatic adenocarcinoma [0.03%]
Kai Sun,Zhi-Xin Song,Xiao-Yun Zhang et al.
Kai Sun et al.
Background: Pancreatic adenocarcinoma (PAAD) ranks among the most lethal human solid tumors, distinguished by its swift progression and limited effective treatment options. The eukaryotic translation initiation factor 3 s...
Comparative roles of Wnt/PCP pathway in midline morphogenesis and cellular flows during non-amniote and amniote gastrulation [0.03%]
Rieko Asai
Rieko Asai
The Wnt/Planar cell polarity (PCP) pathway is evolutionarily conserved and plays crucial roles in coordinating collective cell behaviors during embryonic development. Across the animal kingdom, the bilateral body plan is built upon the midl...
Fernanda C P Mesquita,Stephanie J Kim,Andreia Z Chignalia et al.
Fernanda C P Mesquita et al.
Human pluripotent stem cells (hPSCs) offer a versatile platform for modeling human cardiac development and generating cardiomyocytes for research and translational applications. Cardiac differentiation protocols are well established and rel...
Machine learning-derived AS and AIS scores leverage BCAA metabolism and IL4I1 activity for prognosis and tailored therapy in ccRCC [0.03%]
Kang Qiang Weng,Xin Li,Xiao Bao Chen et al.
Kang Qiang Weng et al.
Background and objective: Renal cell carcinoma (RCC) is among the most prevalent malignant tumors globally, characterized by a poor prognosis. The 5-year survival rate for advanced clear cell renal cell carcinoma (ccRCC) ...
Danggui Shaoyao San ameliorates neuroinflammation in a D-galactose-induced Alzheimer's disease rat model by suppressing the JAK2/STAT3 pathway and modulating Th17/Treg -related immune dysregulation [0.03%]
Gangying Fu,Shuyao Tang,Xin Sun et al.
Gangying Fu et al.
Objective: This study investigates the therapeutic potential of Danggui Shaoyao San (DSS), a traditional Chinese herbal formula, focusing on its effects on Th17/Treg -associated immune regulation and the JAK2/STAT3 signal...
Tumor microenvironment-activated ferritin nanovector enables enhanced tumor delivery of KRASG12C inhibitors and degraders [0.03%]
Annalisa Pia Abbinantefina,Claudia Tito,Silvia Masciarelli et al.
Annalisa Pia Abbinantefina et al.
Mutations in RAS oncogenes (KRAS, HRAS, NRAS) are among the most common genetic alterations in human cancers. The activating KRASG12C mutation, in particular, is a key driver in a significant percentage of non-small cell lung cancer (NSCLC)...