The relationship between sarcopenia and breast cancer: mechanistic pathways and clinical relevance [0.03%]
肌少症与乳腺癌的关系：机制途径和临床意义
Yuheng Wu,Hongliang Cao,Mengxin Li et al.
Yuheng Wu et al.
Breast cancer is the most frequently diagnosed malignancy among women worldwide and one of the leading causes of cancer-related mortality. Despite advances in screening and therapeutic strategies, its prevention and treatment continue to fa...
Eleanor Ralston,Charlotte Haskayne
Eleanor Ralston
Cell line misidentification and cross contamination continue to undermine research quality despite improved laboratory practices. Short Tandem Repeat (STR) profiling remains the primary method for human cell line authentication and is incre...
A discovery protein panel for brain predicted age discordance using MRI in neurologically healthy individuals [0.03%]
基于磁共振的健康人脑预测年龄差异的发现蛋白标志物谱型研究
Jessica M Gill,Arum Lim,Carrie Esopenko et al.
Jessica M Gill et al.
Background and objectives: Brain age is a global measure that compares structural brain MRI with large reference datasets. Predicted age deviation (PAD) is the deviation between predicted brain age and chronological age, ...
Reduced CH25H expression defines a high membrane fluidity, trogocytosis active state in colon cancer stem cells [0.03%]
结肠癌干细胞中CH25H表达降低定义了高膜流动性、活化trogocytosis的状态
Minho Jang,Yoonseo Park,Jeonghyun Kim et al.
Minho Jang et al.
Introduction: Trogocytosis enables direct membrane exchange between contacting cells and has recently been implicated in tumor immune evasion. However, the cellular states and molecular mechanisms that regulate cancer cel...
Machine learning-based models for predicting the efficacy and safety of recombinant human interleukin-11 in the treatment of cancer therapy-induced thrombocytopenia: exploration and preliminary validation from a multicenter retrospective study [0.03%]
基于机器学习的模型预测rhIL-11治疗癌症化疗所致血小板减少症疗效及安全性的研究：多中心回顾性研究的探索与初步验证
Yingmei Wen,Jinxiong Xia,Yi Dong et al.
Yingmei Wen et al.
Introduction: Cancer therapy-induced thrombocytopenia (CTIT) is a common hematologic toxicity associated with anti-tumor treatment. Recombinant human interleukin-11 (rhIL-11), as a thrombopoietic agent, is widely used in ...
Correction: Development and clinical validation of a nursing risk prediction model for chemotherapy-induced febrile neutropenia in patients with cancer [0.03%]
纠正：用于癌症患者化疗所致发热性中性粒细胞减少症护理风险预测模型的建立和临床验证
Fang Xie,Dongmei Zheng,Na Chen et al.
Fang Xie et al.
[This corrects the article DOI: 10.3389/fcell.2026.1779406.]. Keywords: chemotherapy; clinical prediction mo...
Bijal Kikani,Sarah Stanley,Aparna Ramasubramanian
Bijal Kikani
Phakomatoses are a heterogenous group of congenital neurocutaneous syndromes that are associated with a wide range of ocular and systemic presentations. The ocular conditions are important to consider as they may be asymptomatic early on, b...
Ischemic preconditioning promotes hepatic differentiation in human liver organoids [0.03%]
缺血性预处理促进人体肝脏类器官的肝细胞分化
Maura Cimino,Rosaria Tinnirello,Andrea Orlando et al.
Maura Cimino et al.
Introduction: Liver regeneration is essential for successful outcomes after liver transplantation. However, ischemia-reperfusion injury (IRI) remains a major determinant of graft dysfunction that can profoundly affect hep...
m6A RNA modification: a central epitranscriptomic switch orchestrating oncogenic signaling and glycolytic reprogramming in cancer [0.03%]
m６A RNA修饰：一个在癌症中调控致癌信号和糖酵解重组的表遗传中心开关
Yonggang Guo,Ruilong Kou,Zhizhong Huang et al.
Yonggang Guo et al.
N6-methyladenosine (m6A) is the most widespread, abundant, and conserved post-transcriptional modification in eukaryotic RNA, and it participates in the regulation of various biological processes, especially playing a crucial role in tumori...
From metabolism to genome integrity: NRF2 as a key mediator of cancer therapy response [0.03%]
从代谢到基因组稳定性：NRF2作为癌症治疗反应的关键调解因素
Andrea Sarrecchia,Claudia Di Girolamo,Irene Taddei et al.
Andrea Sarrecchia et al.
Metabolic rewiring in cancer is sustained by deregulated intracellular signaling, frequently due to genetic mutation of oncogenes, tumor suppressors or oncometabolite genes. These mutations strongly affect the activity of Transcription Fact...