Immunolocalization and proteomic analyses of IZUMO1 in porcine spermatozoa [0.03%]
免疫组化及蛋白质组分析猪精子IZUMO1的定位分布
Miranda Hernández-Falcó,Paula Sáez-Espinosa,Andrea López-Botella et al.
Miranda Hernández-Falcó et al.
Reproduction is fundamental to breeding programs aimed at increasing productivity in swine industry. However, the application of in vitro embryo production in this species is limited because of the polyspermy. Therefore, characterizing prot...
Based on TransRes-Pix2Pix network to generate the OBL image during SMILE surgery [0.03%]
基于TransRes-Pix2 Pix网络的SMILE手术OBL图像生成方法
Zeyu Zhu,Peifen Lin,Lingling Zhong et al.
Zeyu Zhu et al.
Aim: Generative adversarial networks (GANs) were employed to predict the morphology of OBL before femtosecond laser scanning during SMILE. Methods: ...
The potent neuroepithelium-promoting activity of Otx2 during gastrulation, as demonstrated by its exogenous epiblast-wide expression in chicken embryos [0.03%]
OTX2在胚前期具有强大的神经上皮诱导活性并在鸡胚胎中表现出外源广泛表达入外胚层的能力
Naoya Takami,Kagayaki Kato,Koya Yoshihi et al.
Naoya Takami et al.
Although Otx2 has been a topic of research for over 3 decades, the role of Otx2 expressed in the brain-forming anterior epiblast during gastrulation has not been clarified. We focused on epiblast regions where Otx2 expression is absent or d...
Sven Schumann,Jan R Munk,Michael J Schmeisser et al.
Sven Schumann et al.
Background: In 1912, the veterinary anatomist Eberhard Ackerknecht described morphologically highly variable epithelial invaginations behind the medial mandibular incisors. This orobasal organ (of Ackerknecht) is present ...
"Proteinjury": a universal pathological mechanism mediated by cerebrospinal fluid in neurodegeneration and trauma [0.03%]
蛋白质损伤：脑脊液介导的神经退行性和创伤性疾病中的普遍病理机制
Vladimir F Lazarev,Bashar A Alhasan,Irina V Guzhova et al.
Vladimir F Lazarev et al.
Cerebrospinal fluid (CSF) is a vital body fluid that supports the normal physiological functions of the brain and spinal cord. However, pathological conditions associated with injuries and neurodegenerative diseases lead to the accumulation...
Architecture and molecular machinery of skeletal myofibers: a systematic review of the structure-function relationships [0.03%]
骨骼肌原纤维的结构与功能关系的系统综述：分子和机械装置
Jing Zhao,Xu Du,Wei Fang et al.
Jing Zhao et al.
The skeletal muscle, one of the largest tissues in mammals, plays a crucial role in maintaining body movement and energy metabolism. Dysfunction or damage to the skeletal muscle can lead to various muscle diseases, such as muscular dystroph...
Nodal and cripto-1: distinct functions regulate trophoblast specification in mouse pregnancy [0.03%]
Nodal和Cripto-1：不同的功能调节小鼠妊娠中的合胞体滋养层特异性
Laura Girardet,Neha Kamath,Daniel Dufort
Laura Girardet
Introduction: Proper placentation is essential for fetal growth and development in mammals. Nodal signaling is essential to ensure proper embryo development and requires Cripto-1 as a co-receptor. Both factors have been s...
Comprehensive analyses of telomerase component DKC1 and its association with clinical, molecular and immune landscapes in uterine corpus endometrial carcinoma [0.03%]
全面分析端粒酶成分DKC1及其与子宫体子宫内膜癌临床、分子和免疫特征关联的关系
Chenxi Sun,Xu Liu,Tiantian Liu et al.
Chenxi Sun et al.
Background: Telomerase activation is essential to malignant transformation and progression including uterine corpus endometrial carcinoma (UCEC), while telomerase co-factor DKC1-mediated RNA pseudouridylation is required ...
CNOT6L regulates energy metabolism in the ovarian granulosa cells associated with polycystic ovary syndrome [0.03%]
CNOT6L调节与多囊卵巢综合征相关的卵巢颗粒细胞能量代谢
Shan Han,Yanqiu Xie,Jiale Lv et al.
Shan Han et al.
The endocrine functions exerted by ovarian granulosa cells (GCs) are crucial factors in maintaining follicle development, as oocyte development relies on providing energy substrates and cytokines by ovarian granulosa cells. The mRNA deadeny...