FGF2 supports NANOG expression via pyruvate dehydrogenase-dependent histone acetylation under low oxygen conditions [0.03%]
FGF2通过依赖丙酮酸脱氢酶的组蛋白乙酰化在低氧条件下支持NANOG的表达
Petr Fojtík,Martin Senfluk,Katerina Holomkova et al.
Petr Fojtík et al.
Introduction: The safe and effective application of human pluripotent stem cells (hPSCs) in research and regenerative medicine requires precise control over pluripotency and cell fate. Pluripotency is characterized by hig...
Extracellular matrix stiffness regulates the proliferation and migration capacities of lymphatic endothelial cells via FAT1 [0.03%]
基质刚度通过FAT1调节淋巴内皮细胞的增殖和迁移能力
Zhangrun Xu,Jian Yu,Dandan Chen et al.
Zhangrun Xu et al.
Introduction: The extracellular matrix (ECM) stiffness serves as a critical biomechanical regulator of cellular behavior. However, its specific roles on lymphatic endothelial cells (LECs) remains poorly characterized, par...
The role and targeting strategies of non-coding RNAs in immunotherapy resistance in oral squamous cell carcinoma [0.03%]
非编码RNA在口腔鳞状细胞癌免疫治疗抵抗中的作用和靶向策略
Zhinan Liang,Yicheng Zhao,Xin Wang et al.
Zhinan Liang et al.
Oral squamous cell carcinoma (OSCC) represents a major global health burden, with resistance to immune checkpoint inhibitors (ICIs) posing a significant barrier to effective immunotherapy. Emerging evidence implicates non-coding RNAs (ncRNA...
ePWV as a scalable risk factor for large-scale glaucoma screening: evidence from a national Chinese cohort [0.03%]
中国全国队列中的证据：ePWV是一个可扩展的大型青光眼筛查危险因素
Yupeng Xu,Zihan Yin,Qiaoyun Gong et al.
Yupeng Xu et al.
Background: To examine the association between estimated pulse wave velocity (ePWV), a marker of arterial stiffness, and glaucoma incidence in Chinese cohort, highlighting ePWV's potential as a scalable population-level r...
Whole-body vibration training improves muscle mass and strength in older adults through intra- and extra-muscular pathways [0.03%]
全身振动训练通过肌肉内和肌肉间途径改善老年人的肌肉质量和力量
Xiangyang Tian,Shaoting Fu,Jing He et al.
Xiangyang Tian et al.
Sarcopenia, a geriatric syndrome characterized by the age-related loss of muscle mass and function, is increasingly recognized to be a dynamic process and exists bidirectional transitions with both possible worsening or improving transition...
Correction: Insights into O-GlcNAcylation and programmed cell death in cancer [0.03%]
关于O-连接的N-乙酰氨基葡萄糖基化与癌症程序性细胞死亡的新见解（更正）
Frontiers Editorial Office
Frontiers Editorial Office
[This corrects the article DOI: 10.3389/fcell.2025.1560491.]. Keywords: O-GlcNAcylation; apoptosis; autophag...
Functional impacts of lactylation in Hypoxia‒primed mesenchymal stromal cells [0.03%]
缺氧预处理的间充质基质细胞中乳酰化的功能影响
Fanyi Zhao,Qixing Tang,Jie Liu
Fanyi Zhao
Hypoxic culture (1-5% O2) significantly enhances the biological activity and therapeutic potential of mesenchymal stromal cells (MSCs) by activating the HIF-1α signaling pathway. This activation promotes stemness maintenance, enhances prol...
SQOR as a metabolic rheostat of H2S: structure, redox homeostasis, and disease therapy [0.03%]
调控硫化氢代谢的分子开关SQOR：结构、氧化还原稳态和疾病治疗作用
Ming-Hui Peng,Kai-Lun Zhang,Zhong-Wu Ma et al.
Ming-Hui Peng et al.
Sulfide:quinone oxidoreductase (SQOR) is an inner-mitochondrial-membrane enzyme that couples hydrogen sulfide oxidation to the coenzyme Q pool, thereby linking sulfur metabolism with cellular bioenergetics and redox control. Recent structur...
L-cysteine mitigates busulfan-induced testicular injury through modulation of CBS/H2S axis [0.03%]
L半胱氨酸通过调节CBS / H2S轴缓解丁基磷酰氯引起的睾丸损伤
Song Liu,Bin Wei,Han Wei et al.
Song Liu et al.
Global male infertility, characterized by decreased spermatogenesis and sperm quality, is a significant concern. L-cysteine, essential for hydrogen sulfide (H2S) synthesis, offers numerous biological advantages. However, the protective mech...