Real-time approach to evaluate spinal cord topography of motor pool activation during gait [0.03%]
步态过程中实时评估运动神经池激活的脊髓拓扑结构的方法
Priscilla Avaltroni,Germana Cappellini,Francesca Sylos-Labini et al.
Priscilla Avaltroni et al.
Real-time assessment of spinal motor output ("spinal maps") can provide insight into how neural control strategies during walking differ between healthy individuals and patients with neurological disorders. Abnormal spatiotemporal activatio...
Accessible 2D video-based system for gait kinematic analysis: an inter-rater reliability study [0.03%]
一种步态运动学分析的二维视频系统及其评分者间信度研究
Albert Puig-Diví,Lluís Costa-Tutusaus,Juanjo García-Gil et al.
Albert Puig-Diví et al.
Introduction: Quantitative gait analysis supports clinical decision-making and outcome monitoring, yet its use remains largely restricted to specialized laboratories due to cost and operational complexity. Smartphone-base...
Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to p-aminobenzenesulfonamide [0.03%]
硝基磺胺的生物催化还原：酶工程、工艺整合及对氨基苯磺酸的可持续合成路径
Rui Ai,Noor Muhammad,Yuelong Cui et al.
Rui Ai et al.
Sulfonamides remain important to medicinal and fine-chemical production but conventional aniline precursor routes like Pd-catalysed hydrogenation and Béchamp reductions carry sustainability, safety, and chemoselectivity challenges, especia...
Deep learning-based estimation of sagittal spinal alignment from coronal radiographs [0.03%]
基于深度学习的从侧位X光片估计冠状面脊柱排列参数的方法
Tito Bassani,Riccardo Cecchinato,Marco Brayda-Bruno et al.
Tito Bassani et al.
Introduction: Patient-specific sagittal alignment parameters are essential for accurate biomechanical modeling of the spine. These parameters are typically derived from biplanar radiographs, which, despite low-dose advanc...
Biomechanical effects of cortical bone trajectory and hybrid CBT-TT fixation on fusion-site mechanics and adjacent segment loading: a finite element study [0.03%]
皮质骨轨迹和混合皮质骨轨迹-椎弓根螺钉固定对融合节段及邻近节段生物力学影响的有限元分析
Panpan Hu,Juncai Lei,Fengliang Wu et al.
Panpan Hu et al.
Background: Posterior lumbar interbody fusion (PLIF) with pedicle screw fixation is a standard treatment for degenerative spinal disorders. However, rigid fixation may accelerate adjacent segment degeneration (ASD). Corti...
Biomaterial-based strategies for osteoporosis treatment and bone regeneration: advances and translational challenges [0.03%]
用于骨质疏松症治疗和骨再生的生物材料策略：进展与转化挑战
Xiaoqin Qiu,Ya Ren
Xiaoqin Qiu
Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass, deterioration of bone microarchitecture, and increased susceptibility to fragility fractures. Although conventional antiresorptive and anabolic drugs effective...
Directed evolution of chlorotoxin enhances MMP-2 recognition and improves CAR-T-cell activity in glioblastoma models in vitro [0.03%]
氯毒素定向进化增强MMP-2识别并改善CAR-T细胞在胶质母细胞模型中的活性
Anna Hajdara,Árpád Szöőr,József Murányi et al.
Anna Hajdara et al.
Background: Cysteine-rich miniproteins from venomous animals are promising therapeutic scaffolds due to their compact structure, high stability, and low immunogenicity. Chlorotoxin (CTX), a miniprotein derived from scorpi...
Impact of processing steps on cellular content of mechanical isolated stromal vascular fraction [0.03%]
不同处理步骤对机械法分离所得血管基质组分细胞内容物的影响
Marie-Sophie Narzt,Ruth Cardoza,Sandra Milić et al.
Marie-Sophie Narzt et al.
Adipose tissue derived stromal vascular fraction (SVF) has emerged as cell therapeutic applicable by point-of-care one-step procedures in autologous settings. Even a mechanical isolation, completed within minutes, is typically followed by m...
Biofunctionalization of mineralized collagen with platelet-rich plasma enhances osteogenesis in critical-sized bone defects [0.03%]
富血小板血浆生物功能化矿化胶原促进关键尺寸骨缺损成骨修复
Chong Gao,Yichen Wang,Minghui Qu et al.
Chong Gao et al.
Introduction: Bone defects caused by fractures, nonunion, tumors, or infections severely impair patient quality of life. Although autologous bone grafting remains the gold standard, its limited donor availability and addi...
A finite element-based comparative dynamic biomechanical study of a novel oblique lateral locking plate system (OLLPS) versus traditional internal fixations for oblique lumbar interbody fusion (OLIF) under whole-body vibration [0.03%]
一种新型斜侧锁定钢板系统(OLLPS)与传统内固定技术在全身影震动下进行斜仰式腰椎融合术(OLIF)的生物力学对比研究
Yinge Wang,Xiaoming Fu,Dan He et al.
Yinge Wang et al.
Objective: To evaluate the biomechanical performance of the novel OLLPS in OLIF surgery, including its dynamic stability and application safety, thereby providing evidence-based support for optimizing OLIF combined intern...