Izarra Pablo,Zohdy Marwa,Beltraminelli Helmut et al.
Izarra Pablo et al.
Dermatofibromas (DFs) are benign neoplasms of the dermis typically found on the extremities of young adults. In approximately 3-5% of cases, basaloid cell hyperplasia (BCH) is observed overlying DFs. BCH is characterized by the proliferatio...
Sean Lider,Chanel Mandap,Pavandeep Gill
Sean Lider
There are many benign skin neoplasms encountered in dermatopathology practice that can be associated with underlying genetic disorders. Although benign themselves, these lesions can offer insight into the potential for development of intern...
Unilateral Acroangiodermatitis: From Histopathologic Confirmation to Treatment with PDL [0.03%]
单侧acroangiodermatitis的诊治:从组织病理学确诊到用PDL治疗
André Aparício Martins,José Carlos Cardoso,André Pinho
André Aparício Martins
Acroangiodermatitis is an uncommon angioproliferative dermatosis, related to chronic circulatory diseases, such as chronic venous insufficiency and arteriovenous malformations. We describe the case of a 32-year-old healthy male presenting w...
Diagnostic Challenges in HHV-8-Associated Multicentric Castleman Disease in a Patient with Prior Kaposi Sarcoma [0.03%]
一位既往患有卡波西肉瘤的患者诊断与HHV-8相关多中心Castleman病的挑战
Seraphima S Sidhom,Luke A Laconi,Christopher A LaFond et al.
Seraphima S Sidhom et al.
Human herpesvirus-8 (HHV-8)-associated multicentric Castleman disease (MCD) is a rare lymphoproliferative disorder with systemic and cutaneous manifestations that can be diagnostically challenging, especially in immunocompromised patients. ...
Treatment Resistant Acneiform Eruption in a Young Female: A Diagnostic Pitfall [0.03%]
年轻女性耐药性痤疮样皮疹的诊断陷阱
Ioannis-Alexios Koumprentziotis,Evdoxia Panou,Antonis Tsimpidakis et al.
Ioannis-Alexios Koumprentziotis et al.
A 27-year-old female with no significant medical or dermatologic history presented with a persistent acneiform eruption on the face. The patient had been treated with multiple topical and systemic anti-acne treatments with no significant im...
Molecular and Genetic Markers for Malignant Melanoma: Implications for Prognosis and Therapy [0.03%]
恶性黑色素瘤的分子和基因标志物:对预后和治疗的意义
Lauren Fleshner,Alyssa Sayegh,Mehmet Fatih Atak et al.
Lauren Fleshner et al.
Despite therapeutic advancements, malignant melanoma remains a leading cause of skin cancer-related mortality, with incidence continuing to rise globally. Traditional prognostic tools offer important clinical guidance but fail to capture th...
Mimicking the LOX-Related Autosomal Recessive Congenital Ichthyosis Skin Disease Using a CRISPR-Cas9 System and Unravelling 12S-LOX Function in the Skin [0.03%]
利用CRISPR-Cas9系统模拟LOX相关常染色体隐性先天鱼鳞病并揭示皮肤中12S-LOX的功能
Carolyne Simard-Bisson,Sébastien Larochelle,Véronique J Moulin et al.
Carolyne Simard-Bisson et al.
Stratum Corneum (SC) formation in the human epidermis requires lipid processing. Lipoxygenases (LOXs) such as 12R-Lipoxygenase (12R-LOX) and Epidermis-type lipoxygenase 3 (eLOX-3) contribute to this process. Mutations in their genes cause A...
Prognostic Value of Immunohistochemical T-Cell Marker Loss in Early-Stage Mycosis Fungoides: A Single-Center Cohort Study [0.03%]
免疫组化T细胞标志物丢失在早期蕈样肉芽肿中的预后价值:单中心队列研究
Sandra Jerkovic Gulin,Ivana Ilic,Dario Gulin et al.
Sandra Jerkovic Gulin et al.
Introduction: Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma, often exhibiting loss of pan-T-cell markers such as CD2, CD3, CD5, and CD7. While these immunophenotypic alterations assist in diagnosis, ...
Lamia Alakrash,Renad AlKanaan,Rema Aldihan et al.
Lamia Alakrash et al.
Dermatofibroma is a common mesenchymal skin lesion that typically presents as a firm, slow-growing nodule. Generally, such lesions are asymptomatic; however, they can also cause discomfort in some cases. Ulceration is an uncommon feature of...
Reply to Demiral et al. Comment on "Mahmood, M.N. Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site. Dermatopathology 2024, 11, 52-61" [0.03%]
对Demiral等人的评论的答复:"Mahmood, M.N. 皮肤和口腔黏膜直接免疫荧光:选择最佳活检部位指南。Dermatopathology 2024, 11, 52-61"文章的回复
Muhammad N Mahmood
Muhammad N Mahmood
I have reviewed the insightful comments on my review article titled "Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site" [...].