Michèle Ramsay,Thandiswa Ngcungcu,Wayne Grayson
Michèle Ramsay
Keratolytic winter erythema (KWE) is a rare autosomal dominant keratoderma affecting primarily the palms and soles, manifesting with recurrent waves of erythema followed by epidermal peeling. The condition is so named in view of its anecdot...
Koraisha Hoosen,Anisa Mosam,Ncoza Cordelia Dlova et al.
Koraisha Hoosen et al.
Background: The global mortality from HIV and the cutaneous burden of infective, inflammatory and malignant diseases in the setting of AIDS have significantly declined following the advent of highly active antiretroviral ...
Peri-Umbilical Lymphangioma Circumscriptum Associated with Intra-Abdominal Lymphatic Malformations [0.03%]
与腹腔淋巴管畸形伴发的脐周蔓状淋巴管瘤病
Bhavna Singh,Koraisha Hoosen
Bhavna Singh
A 12-year-old African female presented with a 6-year history of relatively asymptomatic umbilical lesions. On clinical examination, the lesions were papillomatous, violaceous nodules and translucent papules with a serosanguineous discharge....
Karen Koch,Wayne Grayson
Karen Koch
Scleroderma is a rare complication of carcinoid syndrome and is usually encountered in the setting of a metastatic primary neuroendocrine tumour of the distal ileum. Associated endocardial fibrosis is a frequent finding and the condition ca...
Rhabdomyosarcoma Arising in a Giant Congenital Melanocytic Naevus: Case Report and Literature Review [0.03%]
巨先天性黑色素痣并发横纹肌肉瘤一例及文献复习
Tirelo M Pitjadi,Reubina Wadee,Wayne Grayson
Tirelo M Pitjadi
Giant congenital melanocytic naevi (GCN) are rare, disfiguring lesions which carry a significant risk of malignant transformation. Melanoma is the most common malignancy documented in association with these lesions. Although exceedingly rar...
Anisa Mosam,Koraisha Hoosen,Ncoza C Dlova
Anisa Mosam
An HIV-positive female on antiretroviral therapy (ART) presented with an annular eruption diagnosed as a drug reaction based on histology of a lichenoid dermatitis. She responded to oral steroid therapy and discontinuation, but progressed t...
Malignant Chondroid Syringoma: A Report of Two Cases with a Sarcomatous Mesenchymal Component [0.03%]
恶性粘液样海绵状肿瘤：附两例具有肉瘤样间叶成分的病例报告
Carolina Elizabeth Nel,Dawn van der Byl,Wayne Grayson
Carolina Elizabeth Nel
Malignant chondroid syringoma (MCS; malignant mixed tumour) is a rare neoplasm typically arising on the extremities and trunk. We are report 2 unique cases of MCS, one occurring on the scalp of a 78-year-old man and the other on the trunk o...
John Frean,Wayne Grayson
John Frean
The rickettsiae are a diverse group of vector-borne zoonotic bacterial pathogens. The two common spotted fever diseases in existence in southern Africa are boutonneuse fever-like tick bite fever (TBF), caused by Rickettsia conorii, and Afri...
Nelesh P Govender,Wayne Grayson
Nelesh P Govender
In 2013, a novel thermally dimorphic fungal pathogen was described to cause disseminated disease among persons living with advanced HIV/AIDS in South Africa. Although the organism was initially described as an Emmonsia-like fungus, it is no...
Emerentienne Larivé,Michael Nicolas,Gürkan Kaya et al.
Emerentienne Larivé et al.
Purpose: To assess the role of the canonical Wnt pathway via activation of β-catenin in tumor progression of conjunctival melanoma. Methods: ...