Mimicking the LOX-Related Autosomal Recessive Congenital Ichthyosis Skin Disease Using a CRISPR-Cas9 System and Unravelling 12S-LOX Function in the Skin [0.03%]
利用CRISPR-Cas9系统模拟LOX相关常染色体隐性先天鱼鳞病并揭示皮肤中12S-LOX的功能
Carolyne Simard-Bisson,Sébastien Larochelle,Véronique J Moulin et al.
Carolyne Simard-Bisson et al.
Stratum Corneum (SC) formation in the human epidermis requires lipid processing. Lipoxygenases (LOXs) such as 12R-Lipoxygenase (12R-LOX) and Epidermis-type lipoxygenase 3 (eLOX-3) contribute to this process. Mutations in their genes cause A...
Prognostic Value of Immunohistochemical T-Cell Marker Loss in Early-Stage Mycosis Fungoides: A Single-Center Cohort Study [0.03%]
免疫组化T细胞标志物丢失在早期蕈样肉芽肿中的预后价值：单中心队列研究
Sandra Jerkovic Gulin,Ivana Ilic,Dario Gulin et al.
Sandra Jerkovic Gulin et al.
Introduction: Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma, often exhibiting loss of pan-T-cell markers such as CD2, CD3, CD5, and CD7. While these immunophenotypic alterations assist in diagnosis, ...
Lamia Alakrash,Renad AlKanaan,Rema Aldihan et al.
Lamia Alakrash et al.
Dermatofibroma is a common mesenchymal skin lesion that typically presents as a firm, slow-growing nodule. Generally, such lesions are asymptomatic; however, they can also cause discomfort in some cases. Ulceration is an uncommon feature of...
Reply to Demiral et al. Comment on "Mahmood, M.N. Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site. Dermatopathology 2024, 11, 52-61" [0.03%]
对Demiral等人的评论的答复："Mahmood, M.N. 皮肤和口腔黏膜直接免疫荧光：选择最佳活检部位指南。Dermatopathology 2024, 11, 52-61"文章的回复
Muhammad N Mahmood
Muhammad N Mahmood
I have reviewed the insightful comments on my review article titled "Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site" [...].
Comment on Mahmood, M.N. Direct Immunofluorescence of Skin and Oral Mucosa: Guidelines for Selecting the Optimum Biopsy Site. Dermatopathology 2024, 11, 52-61 [0.03%]
马胡德(Mahmood, M.N.)评论：皮肤和口腔黏膜直接免疫荧光：选择最佳活检部位的指南。《皮肤病学病理学》2024年，第11卷，52-61页
Şebnem Demiral,Yunus Özcan,Mehmet Gamsızkan
Şebnem Demiral
Compilation written by Muhammad N [...]. Keywords: direct immunofluorescence; immunopathology; vesiculobullo...
Immunohistochemical Characterisation of the Interstitial Inflammatory Environment: T-Cell- and B-Cell-Dominant Subtypes of Hidradenitis Suppurativa [0.03%]
免疫组织化学特征性表征间质炎症环境：顶囊肿炎T细胞和B细胞为主的亚型
Nessr Abu Rached,Stefanie Bruckmüller,Martin Doerler et al.
Nessr Abu Rached et al.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a complex immune response. Given the considerable heterogeneity of the clinical phenotype of HS, this study aimed to analyse the immunohisto...
Pilomatricoma in Syndromic Contexts: A Literature Review and a Report of a Case in Apert Syndrome [0.03%]
遗传性综合征背景下的皮瘤矩阵瘤的文献回顾及Apert综合征相关病例报告
Gianmarco Saponaro,Elisa De Paolis,Mattia Todaro et al.
Gianmarco Saponaro et al.
Pilomatricomas are benign tumors originating from hair follicle matrix cells and represent the most common skin tumors in pediatric patients. Pilomatricomas may be associated with genetic syndromes such as myotonic dystrophy, familial adeno...
Immunohistopathological Analysis of Spongiosis Formation in Atopic Dermatitis Compared with Other Skin Diseases [0.03%]
特应性皮炎与其他皮肤病海绵形成免疫组化病理分析
Ryoji Tanei,Yasuko Hasegawa
Ryoji Tanei
Whether the spongiotic reaction caused by the interaction of keratinocytes, T-lymphocytes, inflammatory dendritic epidermal cells (IDECs), and Langerhans cells (LCs) observed in atopic dermatitis (AD) represents a common feature of spongios...
Dermatopathological Challenges in Objectively Characterizing Immunotherapy Response in Mycosis Fungoides [0.03%]
描述免疫检查点抑制剂治疗蕈样肉芽肿客观反应的皮肤病理学挑战
Amy Xiao,Arivarasan Karunamurthy,Oleg Akilov
Amy Xiao
In this review, we explore the complexities of objectively assessing the response to immunotherapy in mycosis fungoides (MF), a prevalent form of cutaneous T-cell lymphoma. The core challenge lies in distinguishing between reactive and mali...
Non-Invasive Diagnostic Techniques in Penile Intraepithelial Neoplasia (PeIN): Insights from Reflectance Confocal Microscopy (RCM), Line-Field Confocal Optical Coherence Tomography (LC-OCT), and Correlation with Histopathological Features [0.03%]
阴茎原位癌非侵入性诊断技术：反射式共聚焦显微镜、线场共焦光学相干断层扫描与组织病理学特征相关性的见解
Caterina Damiani,Cesare Ariasi,Giuseppe La Rosa et al.
Caterina Damiani et al.
Penile intraepithelial neoplasia (PeIN) is a rare but clinically significant condition that can progress to invasive squamous carcinoma. Early diagnosis is crucial but often challenging due to its heterogeneous clinical and dermoscopic pres...