PRAME Expression in Melanoacanthomas: Expanding the Spectrum of Positive Melanocytes in Sun-Exposed Skin [0.03%]
PRAME在melanoacanthoma中的表达：日晒皮肤中阳性黑素细胞谱系的扩展
Francesco Fortarezza,Anna Poputchikova,Federica Pezzuto et al.
Francesco Fortarezza et al.
PRAME (Preferentially Expressed Antigen in Melanoma) is increasingly used as an immunohistochemical marker in the evaluation of melanocytic lesions; however, its expression in benign melanocytic proliferations remains incompletely character...
Francoise Plantier,Fiona Lewis
Francoise Plantier
Biopsies are only performed in less than 1% of all consultations dedicated to paediatric genital dermatology. The objectives of this paper are to review and clarify the histopathological features of the conditions most often biopsied: first...
Cutaneous Granular Cell Tumor with Overlying Hypertrichosis in an Adult: A Rare Case Report [0.03%]
成人皮肤颗粒细胞瘤伴表皮毛发增多症一例报告
Yara Alhusaini,Abdulaziz Almufadhi,Naif Alzahrani et al.
Yara Alhusaini et al.
Granular cell tumors are uncommon neoplasms of neural origin that may involve the skin and often present with nonspecific clinical features, making diagnosis challenging. Cutaneous granular cell tumors rarely exhibit overlying hypertrichosi...
A Case of Recurrent Chromoblastomycosis Treated with Multiple Surgical Management Options [0.03%]
复发性chromoblastomyosis的多模式手术治疗病例报告
Madeleine Kelly,Crystal Williams,Robert Miller
Madeleine Kelly
Chromoblastomycosis is a chronic mycosis of the skin and subcutaneous tissue typically caused by traumatic inoculation of dematiaceous fungi of the Herpotrichiellaceae. A 59-year-old male presented with a 12-month history of an asymmetrical...
Defining Histological Patterns in Inherited Ichthyoses: Toward a Diagnostic Algorithm Based on 66 Confirmed Cases [0.03%]
遗传性鱼鳞病的组织病理特征及诊断算法（66例分析）
Kira Süßmuth,Vinzenz Oji,Jacqueline Bodes et al.
Kira Süßmuth et al.
Background: Inherited ichthyoses are a heterogeneous group of disorders of cornification caused by mutations in genes encoding epidermal proteins. Clinically, patients with ichthyosis present with erythema, scaling, and o...
The Unusual Invader in a Patient with Long-Standing Rheumatoid Arthritis: A Case of Leishmania major Colonization of Rheumatoid Nodules [0.03%]
长期类风湿性关节炎患者中的不寻常入侵者：黎巴嫩贾米尔原生动物定植于类风湿结节的一例报告
Monia Di Prete,Viviana Lora,Arianna Lamberti et al.
Monia Di Prete et al.
Rheumatoid nodules are the most common extra-articular manifestation of rheumatoid arthritis. Long-term immunomodulatory therapies, including corticosteroids, used in the management of rheumatoid arthritis are associated with a higher risk ...
Gaia Mancuso,Igor Salvadè,Adam Ogna et al.
Gaia Mancuso et al.
Background: Behçet-like syndrome (BLS) refers to the presence of Behçet's disease (BD) features occurring in association with distinct clinical-pathological conditions such as inborn errors of immunity, myeloproliferati...
Tumor Infiltrating Lymphocytes in Cutaneous Squamous Cell Carcinoma-A Systematic Review [0.03%]
皮肤鳞状细胞癌中肿瘤浸润性淋巴细胞-系统评价
Li Yang Loo,Shi Huan Tay,Choon Chiat Oh
Li Yang Loo
Cutaneous squamous cell carcinoma (cSCC) is an immunogenic malignancy with variable immune infiltration and inconsistent responses to checkpoint blockade. Tumor-infiltrating lymphocytes (TILs) influence tumor progression and therapeutic out...
The Need for Standardization of PRAME Immunohistochemistry in Melanocytic Neoplasms [0.03%]
黑素细胞肿瘤中PRAME免疫组化的标准化必要性
Calla M Sullivan,Dominick DiMaio,Scott Lauer et al.
Calla M Sullivan et al.
Accurate diagnosis of melanomas is crucial for proper evaluation and treatment. One immunohistochemical stain frequently utilized is PRAME (PReferentially expressed Antigen in MElanoma), a tumor-associated antigen expressed in most melanoma...
Deeply Pigmented Reticulated Acanthoma with Sebaceous Differentiation Mimicking Cutaneous Malignancy: A Case Report and Review of the Literature [0.03%]
深染网状棘皮瘤伴脂质分化似皮肤恶性肿瘤：1例报告及文献复习
Padol Chamninawakul,Xiaotian Wu,Joyce S S Lee
Padol Chamninawakul
Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous neoplasm. Its variable clinical presentation frequently mimics both benign and malignant entities, posing a significant diagnostic challenge. We report ...