Alexandre Stahl,Nicolo Riggi,Katya Nardou et al.
Alexandre Stahl et al.
Aims: Conjunctival and cutaneous melanoma partially share similar clinical and molecular backgrounds. As 5-hydroxymethylcytosine (5-hmC) loss has been demonstrated in cutaneous melanoma, we decided to assess if similar ch...
TP53 Abnormalities and MMR Preservation in 5 Cases of Proliferating Trichilemmal Tumours [0.03%]
TP53异常和MMR功能保存在5例增生性毛球瘤中的作用
Raquel Martín-Sanz,José María Sayagués,Pilar García-Cano et al.
Raquel Martín-Sanz et al.
Proliferating trichilemmal tumours (PTT) are defined by a benign squamous cell proliferation inside a trichilemmal cystic (TC) cavity. A possible explanation of this proliferative phenomenon within the cyst may be molecular alterations in g...
The Great Mime: Three Cases of Melanoma with Carcinoid-Like and Paraganglioma-Like Pattern with Emphasis on Differential Diagnosis [0.03%]
大哑剧:3例具有类癌样和副节瘤样模式的黑色素瘤的鉴别诊断重点病例报告
Gerardo Cazzato,Anna Colagrande,Antonietta Cimmino et al.
Gerardo Cazzato et al.
Melanoma is among the most aggressive tumors, with different histological patterns of presentation ranging from the usual and easily diagnosable pictures to complex patterns of difficult diagnostic interpretation. Here, we present three cas...
Ichthyoses-A Clinical and Pathological Spectrum from Heterogeneous Cornification Disorders to Inflammation [0.03%]
鱼鳞病:异质性角化障碍至炎症的临床和病理谱系
Dieter Metze,Heiko Traupe,Kira Süßmuth
Dieter Metze
Ichthyoses are inborn keratinization disorders affecting the skin only (non-syndromic) or are associated with diseases of internal organs (syndromic). In newborns, they can be life-threatening. The identification of the gene defects resulte...
Kyoko Sugioka,Akinobu Hayashi,Masako Ichishi et al.
Kyoko Sugioka et al.
Lymphocytic infiltration of the skin (LIS), first reported by Jessner and Kanof in 1953, is a disease of unknown etiology characterized by erythematous papules and plaques on the head, neck, and upper back and histopathological findings of ...
Carla Stephan,Ossama Abbas,Jag Bhawan
Carla Stephan
The interface dermatitides encompass a vast array of cutaneous entities which, at times, may present with particular clinical variants with adnexal predilection. Similarly, hair follicle and eccrine gland involvement of some of these entiti...
Bilateral Nipple Enlargement as a Secondary Effect of Anabolic Drugs: A Histopathological Mimicker of Smooth Muscle Hamartoma [0.03%]
生长激素相关双侧乳头肥大的活检陷阱——平滑肌错构瘤样结构导致误诊
Mar Llamas-Velasco,Maria Francesca Bianciardi Valassina,Enrique Ovejero-Merino et al.
Mar Llamas-Velasco et al.
Smooth muscle hamartoma are usually solitary and congenital, may affect the genital area and nipples. Histopathologically, they are characterized by the presence of mature smooth muscle bundles. We present a 40 year-old male with bilateral ...
Role of CD123 (+) Plasmacytoid Dendritic Cells in Etiologically Different Variants of Erythema Multiforme: A Monocentric Retrospective Study [0.03%]
以病因不同变异型红斑性肢痛病为特征的CD123⁺浆细胞样树突状细胞的作用:单中心回顾性研究
Hatice B Zengin,Tatsiana Pukhalskaya,Bruce R Smoller
Hatice B Zengin
Plasmacytoid dendritic cells (pDCs) constitute a subset of dendritic cells known to be the "professional" interferon type I (IFN-I) producers. pDCs play an important role in antiviral immunity, as well as linking innate and adaptive immunit...
Pleomorphic Hyalinizing Angiectatic Tumor (PHAT): Review of the Literature with Case Presentation [0.03%]
多形透明变血管瘤(PHAT)的文献回顾及病例报告
Gerardo Cazzato,Anna Colagrande,Antonietta Cimmino et al.
Gerardo Cazzato et al.
Pleomorphic hyalinizing angiectatic tumor (PHAT) is a very rare entity of soft tissue considered a "neoplasm of uncertain behaviour of connective or other soft tissue" by the World Health Organization (2020). It develops in subcutaneous tis...
Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases [0.03%]
口腔苔藓样疾病上皮不典型增生评估的组间和组内差异
Marwa Zohdy,Simone Cazzaniga,Helga Nievergelt et al.
Marwa Zohdy et al.
Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-...