"Animal-Type Melanoma/Pigmented Epithelioid Melanocytoma": History and Features of a Controversial Entity [0.03%]
“动物型黑色素瘤/色素上皮样黑色素细胞瘤”:一个颇具争议实体的历史与特征
Gerardo Cazzato,Francesca Arezzo,Anna Colagrande et al.
Gerardo Cazzato et al.
Animal-type melanoma (ATM) was first described in the literature by Levene in 1979 in relation to a patient with a characteristic clinical presentation, and only later, rare and anecdotal case series have tried to shed light on an entity th...
Matthias Walther,Sandra Falkvoll,Sebastian Leibl
Matthias Walther
Collision tumors consisting of melanoma and squamous cell carcinoma are very rare. We present the case of a deceptive hyperkeratotic nodule on the forearm of a 72-year-old woman, which clinically appeared to be a squamous cell carcinoma, ke...
Histological Patterns of Skin Lesions in Tuberous Sclerosis Complex: A Panorama [0.03%]
结节性硬化症皮肤病变的组织病理图谱:全景分析
Marine Cascarino,Stéphanie Leclerc-Mercier
Marine Cascarino
Tuberous Sclerosis Complex (TSC) is a multisystem genetic disease characterized by cutaneous and extracutaneous hamartomas. The diagnosis is based on the association of major and minor criteria, defined by a consensus conference updated in ...
Evaluation of Melanocyte Loss in Mycosis Fungoides Using SOX10 Immunohistochemistry [0.03%]
SOX10免疫组化在评价蕈样肉芽肿中黑素细胞丢失中的作用评估
Cynthia Reyes Barron,Bruce R Smoller
Cynthia Reyes Barron
Mycosis fungoides (MF) is a subtype of primary cutaneous T-cell lymphoma (CTCL) with an indolent course that rarely progresses. Histologically, the lesions display a superficial lymphocytic infiltrate with epidermotropism of neoplastic T-ce...
Primary Localized Cutaneous Nodular Amyloidosis and Limited Cutaneous Systemic Sclerosis: Additional Cases with Dermatoscopic and Histopathological Correlation of Amyloid Deposition [0.03%]
原发性局限性皮肤结节型淀粉样变和系统性硬化症的皮肤受累:探讨皮损组织病理及皮肤镜特点
Laura Atzori,Caterina Ferreli,Caterina Matucci-Cerinic et al.
Laura Atzori et al.
Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare condition due to the plasma cell proliferation and skin deposition of immunoglobulin light chains, without systemic amyloidosis or hematological dyscrasias. The association w...
A Previously Unrecognized Granulomatous Variant of Gamma-Delta T-Cell Lymphoma [0.03%]
先前未被认识的γδT细胞淋巴瘤肉芽肿型变异体病例报告
Tatsiana Pukhalskaya,Bruce R Smoller,David M Menke et al.
Tatsiana Pukhalskaya et al.
Primary cutaneous γδ T-cell lymphoma (PCGD-TCL) is an extremely rare and aggressive T-cell neoplasm with complex heterogeneity. We present a series of two patients who presented with firm, subcutaneous nodules and were diagnosed with PCGD...
Rishi Agrawal,Daniel Knabel,Anthony P Fernandez
Rishi Agrawal
A 64-year old male presented with a several-year history of an insidious-onset tender, itchy and xerotic rash on his lower legs. Past medical history was significant for Graves' disease and Graves' ophthalmopathy. The examination revealed p...
Histologic Patterns and Clues to Autoinflammatory Diseases in Children: What a Cutaneous Biopsy Can Tell Us [0.03%]
儿童自身炎症性疾病的组织病理模式及线索:皮肤活检能告诉我们什么
Athanassios Kolivras,Isabelle Meiers,Ursula Sass et al.
Athanassios Kolivras et al.
Autoinflammation is defined by aberrant, antigen-independent activation of the innate immune signaling pathways. This leads to increased, pro-inflammatory cytokine expression and subsequent inflammation. In contrast, autoimmune and allergic...
Concurrent Adjacent Merkel Cell Carcinoma and Chronic Lymphocytic Leukemia without Simultaneous Merkel Cell Polyomavirus Detection: A Case Series [0.03%]
并发相邻的默克尔细胞癌和慢性淋巴细胞白血病但没有同时检测到默克尔细胞多瘤病毒:一系列病例分析
Rayan Saade,Saleh Najjar,Mustafa Erdem Arslan et al.
Rayan Saade et al.
Background: The association between Merkel cell carcinoma (MCC) and chronic lymphocytic leukemia/small lymphocytic leukemia (CLL/SLL) is well established in the literature. A majority of MCCs are known to be associated wi...
Stéphanie Leclerc-Mercier
Stéphanie Leclerc-Mercier
The onset of blisters in a neonate or an infant is often a source of great concern for both parents and physicians. A blistering rash can reveal a wide range of diseases with various backgrounds (infectious, genetic, autoimmune, drug-relate...