Indeterminate Subcutaneous Lesion of the Nasal Dorsum in an Adolescent: A Multidisciplinary Approach to a Rare Case of Spindle Cell Lipoma [0.03%]
青少年鼻背部位皮下病变的多学科罕见纺锤细胞脂肪瘤诊疗案例
Alessandro Serrone,Chiara Rustichelli,Gian Luca Fadda et al.
Alessandro Serrone et al.
We report the case of a 16-year-old girl presenting with a painless, clinically stable subcutaneous swelling of the nasal dorsum with a three-year history. Despite an extensive multidisciplinary diagnostic work-up-including dermatological, ...
Histopathologic Features and Molecular Markers of Encephalocraniocutaneous Lipomatosis (ECCL) [0.03%]
脑颅皮脂病的组织病理特征及分子标志物(ECCL)
Siddharth Venigalla,Tanvir K Dhaliwal,Anvita Anumolu et al.
Siddharth Venigalla et al.
Encephalocraniocutaneous lipomatosis (ECCL) is a rare congenital neurocutaneous disorder characterized by ocular, skin, and central nervous system manifestations. Despite its recognizable clinical features, such as nevus psiloliparus, histo...
Comparative Clinicopathological Analysis of Oral Focal Mucinosis and Solitary Cutaneous Focal Mucinosis: A Case Series and Literature-Based Analysis [0.03%]
口腔局灶黏蛋白症与孤立性皮肤局灶黏蛋白症的临床病理比较分析：病例系列及文献综述-based analysis口腔局灶黏蛋白症与孤立性皮肤局灶黏蛋白症的临床病理比较分析：病例系列及文献综述
Wickramasinghe Mudiyanselage Sithma Nilochana Wickramasinghe,Primali Rukmal Jayasooriya,Balapuwaduge Ranjit Rigobert Nihal Mendis et al.
Wickramasinghe Mudiyanselage Sithma Nilochana Wickramasinghe et al.
Background/Objectives: Oral focal mucinosis (OFM) and solitary cutaneous focal mucinosis (SCFM) are rare, benign lesions characterized by localized mucin deposition in the stromal connective tissue. While both share similar histological fea...
Cutaneous Neufibroma in the Absence of Classical NF1 Features: A Case Report and Literature Review [0.03%]
无NF1典型特征的皮肤神经纤维瘤一例报告及文献复习
Christine Suryani Novelita Sutrisno,Desy Hinda Pramita,Ita Puspita Dewi
Christine Suryani Novelita Sutrisno
Neurofibromatosis type 1 (NF1) is a prevalent neurocutaneous illness resulting from mutations in the NF1 gene, usually diagnosed according to clinical criteria set by the National Institutes of Health (NIH). These encompass café-au-lait ma...
Izarra Pablo,Zohdy Marwa,Beltraminelli Helmut et al.
Izarra Pablo et al.
Dermatofibromas (DFs) are benign neoplasms of the dermis typically found on the extremities of young adults. In approximately 3-5% of cases, basaloid cell hyperplasia (BCH) is observed overlying DFs. BCH is characterized by the proliferatio...
Sean Lider,Chanel Mandap,Pavandeep Gill
Sean Lider
There are many benign skin neoplasms encountered in dermatopathology practice that can be associated with underlying genetic disorders. Although benign themselves, these lesions can offer insight into the potential for development of intern...
Unilateral Acroangiodermatitis: From Histopathologic Confirmation to Treatment with PDL [0.03%]
单侧acroangiodermatitis的诊治：从组织病理学确诊到用PDL治疗
André Aparício Martins,José Carlos Cardoso,André Pinho
André Aparício Martins
Acroangiodermatitis is an uncommon angioproliferative dermatosis, related to chronic circulatory diseases, such as chronic venous insufficiency and arteriovenous malformations. We describe the case of a 32-year-old healthy male presenting w...
Diagnostic Challenges in HHV-8-Associated Multicentric Castleman Disease in a Patient with Prior Kaposi Sarcoma [0.03%]
一位既往患有卡波西肉瘤的患者诊断与HHV-8相关多中心Castleman病的挑战
Seraphima S Sidhom,Luke A Laconi,Christopher A LaFond et al.
Seraphima S Sidhom et al.
Human herpesvirus-8 (HHV-8)-associated multicentric Castleman disease (MCD) is a rare lymphoproliferative disorder with systemic and cutaneous manifestations that can be diagnostically challenging, especially in immunocompromised patients. ...
Treatment Resistant Acneiform Eruption in a Young Female: A Diagnostic Pitfall [0.03%]
年轻女性耐药性痤疮样皮疹的诊断陷阱
Ioannis-Alexios Koumprentziotis,Evdoxia Panou,Antonis Tsimpidakis et al.
Ioannis-Alexios Koumprentziotis et al.
A 27-year-old female with no significant medical or dermatologic history presented with a persistent acneiform eruption on the face. The patient had been treated with multiple topical and systemic anti-acne treatments with no significant im...
Molecular and Genetic Markers for Malignant Melanoma: Implications for Prognosis and Therapy [0.03%]
恶性黑色素瘤的分子和基因标志物：对预后和治疗的意义
Lauren Fleshner,Alyssa Sayegh,Mehmet Fatih Atak et al.
Lauren Fleshner et al.
Despite therapeutic advancements, malignant melanoma remains a leading cause of skin cancer-related mortality, with incidence continuing to rise globally. Traditional prognostic tools offer important clinical guidance but fail to capture th...