Desmosomal-Type Acantholysis-A New Histologic Pattern Related to Mutations of Genes for Desmosomal Proteins [0.03%]
与桥粒蛋白基因突变有关的一种新的组织病理表现——类似黏合斑的棘松解现象
Dieter Metze,Kira Süßmuth,Clemens Metze et al.
Dieter Metze et al.
Desmosomes are specialized cell-cell junctions that play a crucial role in maintaining the structural integrity of both cornifying and non-cornifying epithelium. Disruption of desmosomal cohesion in autoimmune, infectious, and other disease...
Bilateral Auricular Blastomycosis-like Pyoderma: A Rare Presentation Histologically Misinterpreted as Squamous Cell Carcinoma [0.03%]
双侧耳廓芽生菌病样皮炎：误诊为鳞状细胞癌的罕见病例
Nazario Pesce,Giorgia Di Marco,Giorgio Stabile et al.
Nazario Pesce et al.
Blastomycosis-like pyoderma (BLP) is a rare chronic inflammatory dermatosis characterized by exuberant vegetative and verrucous plaques, most frequently associated with bacterial colonization, particularly Staphylococcus aureus. Owing to it...
Comprehensive Genomic Profiling of Cutaneous Adnexal Carcinomas: A Genomic Landscape Study [0.03%]
皮肤附属器癌的全面基因组分析——一项基因组景观研究
Maroun Bou Zerdan,Kevin T Jamouss,Alexandre Maalouf et al.
Maroun Bou Zerdan et al.
Cutaneous adnexal carcinomas (CACs) comprise a diverse group of malignant tumors that show morphological differentiation toward one of the four main adnexal structures in normal skin: hair follicles, sebaceous glands, sweat-apocrine glands,...
Longitudinal Melanonychia in Children: Clinical and Histopathologic Features and Management with Literature Update [0.03%]
儿童纵向甲黑线的临床和组织病理特征及治疗（文献更新）
Isabelle Moulonguet,Marie Caucanas,Sophie Goettmann
Isabelle Moulonguet
Longitudinal melanonychia (LM) results from the deposition of pigment in the nail plate due to increased melanocytic activity within the nail matrix. Recent publications on this topic have helped clarify the main clinical, histological, and...
PRAME Expression in Melanoacanthomas: Expanding the Spectrum of Positive Melanocytes in Sun-Exposed Skin [0.03%]
PRAME在melanoacanthoma中的表达：日晒皮肤中阳性黑素细胞谱系的扩展
Francesco Fortarezza,Anna Poputchikova,Federica Pezzuto et al.
Francesco Fortarezza et al.
PRAME (Preferentially Expressed Antigen in Melanoma) is increasingly used as an immunohistochemical marker in the evaluation of melanocytic lesions; however, its expression in benign melanocytic proliferations remains incompletely character...
Francoise Plantier,Fiona Lewis
Francoise Plantier
Biopsies are only performed in less than 1% of all consultations dedicated to paediatric genital dermatology. The objectives of this paper are to review and clarify the histopathological features of the conditions most often biopsied: first...
Cutaneous Granular Cell Tumor with Overlying Hypertrichosis in an Adult: A Rare Case Report [0.03%]
成人皮肤颗粒细胞瘤伴表皮毛发增多症一例报告
Yara Alhusaini,Abdulaziz Almufadhi,Naif Alzahrani et al.
Yara Alhusaini et al.
Granular cell tumors are uncommon neoplasms of neural origin that may involve the skin and often present with nonspecific clinical features, making diagnosis challenging. Cutaneous granular cell tumors rarely exhibit overlying hypertrichosi...
A Case of Recurrent Chromoblastomycosis Treated with Multiple Surgical Management Options [0.03%]
复发性chromoblastomyosis的多模式手术治疗病例报告
Madeleine Kelly,Crystal Williams,Robert Miller
Madeleine Kelly
Chromoblastomycosis is a chronic mycosis of the skin and subcutaneous tissue typically caused by traumatic inoculation of dematiaceous fungi of the Herpotrichiellaceae. A 59-year-old male presented with a 12-month history of an asymmetrical...
Defining Histological Patterns in Inherited Ichthyoses: Toward a Diagnostic Algorithm Based on 66 Confirmed Cases [0.03%]
遗传性鱼鳞病的组织病理特征及诊断算法（66例分析）
Kira Süßmuth,Vinzenz Oji,Jacqueline Bodes et al.
Kira Süßmuth et al.
Background: Inherited ichthyoses are a heterogeneous group of disorders of cornification caused by mutations in genes encoding epidermal proteins. Clinically, patients with ichthyosis present with erythema, scaling, and o...
The Unusual Invader in a Patient with Long-Standing Rheumatoid Arthritis: A Case of Leishmania major Colonization of Rheumatoid Nodules [0.03%]
长期类风湿性关节炎患者中的不寻常入侵者：黎巴嫩贾米尔原生动物定植于类风湿结节的一例报告
Monia Di Prete,Viviana Lora,Arianna Lamberti et al.
Monia Di Prete et al.
Rheumatoid nodules are the most common extra-articular manifestation of rheumatoid arthritis. Long-term immunomodulatory therapies, including corticosteroids, used in the management of rheumatoid arthritis are associated with a higher risk ...