Histopathological Diagnosis of Malignant Melanoma at the Dawn of 2023: Knowledge Gained and New Challenges [0.03%]
2023年伊始的黑色素瘤恶性肿瘤病理诊断：已获知识与新挑战
Gerardo Cazzato
Gerardo Cazzato
Year after year, the incidence and prevalence rates of cutaneous Malignant Melanoma (MM) show a continuous increase and, according to the most up-to-date American Cancer Society (ACS) projections, it is estimated that 97,610 new melanomas w...
Post-Pemphigus Acanthomata Presenting as an Isolated, Hyperkeratotic Plaque [0.03%]
狼疮性天疱疮痊愈后的角化过度性鳞屑状皮疹一例报告
Rachita Pandya,Yanjia Zhou,Mansee Desai et al.
Rachita Pandya et al.
Post-pemphigus acanthomas have been rarely discussed in the literature. A prior case series identified 47 cases of pemphigus vulgaris and 5 cases of pemphigus foliaceus, out of which 13 developed acanthomata as a part of the healing process...
TRPS1 Is Differentially Expressed in a Variety of Malignant and Benign Cutaneous Sweat Gland Neoplasms [0.03%]
TRPS1在多种皮肤汗腺良恶性肿瘤中差异表达
Hatice B Zengin,Chau M Bui,Kristin Rybski et al.
Hatice B Zengin et al.
Neoplasms of sweat glands and the breast may be morphologically and immunophenotypically similar. A recent study showed that TRPS1 staining is a highly sensitive and specific marker for breast carcinoma. In this study, we analyzed TRPS1 exp...
Loss of CD34 Expression within an Interstitial Dermal Lymphoid Cell Infiltrate Is a Helpful Clue to the Diagnosis of Morphea [0.03%]
CD34在真皮间质淋巴细胞浸润中表达的缺失有助于诊断硬化性皮肤炎
Maged Daruish,Anoud Zidan,Danielle T Greenblatt et al.
Maged Daruish et al.
A dermal interstitial lymphocytic infiltrate may represent a diagnostic challenge, particularly if the clinical history is not provided. We present three cases within the histological spectrum of morphea in which the immunohistochemical mar...
An Underrecognized Histologic Clue to the Diagnosis of Mucous Membrane Pemphigoid: A Case Report and Review of Diagnostic Guidelines [0.03%]
口腔黏膜天疱疮的组织病理特征：1例报道及诊断思路梳理
Jason R McFadden,Advaita S Chaudhari,Debra Birenbaum et al.
Jason R McFadden et al.
Mucous membrane pemphigoid (MMP), also known as cicatricial pemphigoid (CP), is a heterogeneous group of subepidermal blistering diseases that affect the mucous membranes, most frequently in the eye and oral cavity. MMP is often unrecognize...
Rare Variants of Dermatofibrosarcoma Protuberans: Clinical, Histologic, and Molecular Features and Diagnostic Pitfalls [0.03%]
皮赘状纤维组织细胞瘤罕见变异型的临床、病理及分子特征和诊断陷阱
Celestine M Trinidad,Sintawat Wangsiricharoen,Victor G Prieto et al.
Celestine M Trinidad et al.
Dermatofibrosarcoma protuberans (DFSP) is a dermal malignant mesenchymal tumor. Most variants are associated with a high risk of local recurrence and a low risk of metastasis. The classic histomorphology of this tumor is made up of uniform,...
Widespread and Long-Enduring Hyperkeratosis Lenticularis Perstans (Flegel's Disease): Clinico-Pathological and Dermoscopic Features of a Rare Presentation [0.03%]
泛发性和持久性的过度角化性 Lentiginous 损害（Flegel病）：罕见病例的临床病理和皮肤镜特征
Giorgio Stabile,Giovanni Paolino,Nathalie Rizzo et al.
Giorgio Stabile et al.
Hyperkeratosis lenticularis perstans, also known as Flegel's disease (FD), is a rare cutaneous disorder affecting mainly the lower extremities of middle-aged people. Due to its rarity, this disease is usually not recognized by physicians re...
Multiply Recurrent Composite Hemangioendothelioma of Penis with Histologic Progression to High-Grade Features [0.03%]
具有高度恶性特征的阴茎复发生复合性血管内皮瘤及组织学进展
Chau M Bui,Bonnie Balzer
Chau M Bui
Composite hemangioendothelioma (CHE) is a very rare low-grade malignant vascular neoplasm. Here, we present the first case of it occurring on a penis with two local recurrences over a 9 year span and its progression to a high-grade morpholo...
Concordance of Clinical, Histologic and Direct Immunofluorescence Findings in Patients with Autoimmune Bullous Dermatoses in Vietnam [0.03%]
越南自身免疫性大疱性皮肤病患者的临床、组织学和直接免疫荧光发现的一致性
Giang Huong Tran,Nhan Thi Ai Le,Minh Hoang Dang et al.
Giang Huong Tran et al.
Introduction: Autoimmune bullous dermatoses (ABD) represent a heterogeneous group of blistering disorders that may be debilitating with high morbidity. Clinical, histological, and direct immunofluorescence (DIF) studies are essential in est...
Epithelioid Fibrous Histiocytoma with CARS-ALK Fusion: First Case Report [0.03%]
上皮样纤维组织细胞瘤伴CARS-ALK融合：首例报道
Léo-Paul Secco,Louis Libbrecht,Elsa Seijnhaeve et al.
Léo-Paul Secco et al.
Epithelioid fibrous histiocytoma (EFH) is a type of uncommon skin tumor mostly harboring Anaplastic Lymphoma Kinase (ALK) gene rearrangement, with different fusion partners reported. Whether this tumor is a separate entity or has a relation...