Pembrolizumab-Induced Lichen Planus Pemphigoides in a Patient with Metastatic Adrenocortical Cancer: A Case Report and Literature Review [0.03%]
转移性肾上腺皮质癌患者的帕博利尤单抗诱导的类天疱疮型扁平苔藓1例及相关文献复习
Vrinda Madan,Mark C Marchitto,Joel C Sunshine
Vrinda Madan
While the advent of immune-checkpoint inhibitors has revolutionized cancer therapy, immune-related adverse effects (irAEs) have also been on the rise. Cutaneous toxicities are among the most common irAEs, especially in the context of progra...
Increased Occurrence of Cutaneous Leiomyomas and Dermatofibromas in Patients with Uterine Leiomyomas without Fumarate Hydratase Gene Mutations [0.03%]
无苹果酸酶基因突变的子宫平滑肌瘤患者皮肤平滑肌瘤和真皮纤维瘤发生率增加
Elena Campione,Monia Di Prete,Gaetana Costanza et al.
Elena Campione et al.
Leiomyomas are smooth muscle-derived benign neoplasms that can affect all organs, most frequently in the uterus. Fumarate hydratase gene (FH) mutation is characterised by an autosomal dominant disease with increased occurrence of renal tumo...
Bortezomib-Induced Reticular Eruption in Patient with Multiple Myeloma [0.03%]
一名多发性骨髓瘤患者使用硼替佐米诱发的网状皮疹病例报告
Joseph Han,Shayan Owji,Aneesh Agarwal et al.
Joseph Han et al.
Bortezomib is the first proteasome inhibitor to treat a variety of malignancies and is currently part of the standard of care regimen for the initial treatment of patients with newly diagnosed multiple myeloma. While bortezomib is generally...
Muhammad N Mahmood
Muhammad N Mahmood
Cutaneous syncytial myoepithelioma is a recently characterized variant of cutaneous myoepithelioma with a distinct histopathological and immunohistochemical profile. It is more common in men and predominately involves upper and lower extrem...
Perforating Gout: Expanding the Differential for Transepidermal Elimination [0.03%]
痛风性穿通病：表皮下物质排除的鉴别诊断扩增
Michal Bohdanowicz,Scott H Bradshaw
Michal Bohdanowicz
Perforating dermatoses are dermatologic disorders with transepidermal elimination (TE) of dermal substances. While TE is typically associated with collagen and elastin, it can also occur as a secondary event in other processes, and it is im...
Cody J Rasner,Yan Zhou,Alessio Giubellino
Cody J Rasner
The recurrent nevus phenomenon represents the persistence of a nevus within a scar from a prior biopsy site, with the acquisition of clinical and histologic features frequently overlapping with those of melanoma, posing relevant diagnostic ...
Folliculosebaceous Cystic Hamartoma with Spindle Cell Lipomatous and Neural Components [0.03%]
伴有梭形细胞脂肪样和神经成分的毛囊皮脂腺囊性错构瘤
Carmelo Urso,Marina Yarygina
Carmelo Urso
Folliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We repor...
Expression of Connexin 43 in Granular Cell Tumors of the Skin, Tongue and Esophagus [0.03%]
皮肤、舌和食道颗粒细胞肿瘤中连接子43的表达
Hermann Kneitz,Verena Frings,Stefan Kircher et al.
Hermann Kneitz et al.
Background: Granular cell tumors (GCT) are rare neoplasms of Schwann cell origin occurring in the skin and in other organs. The etiopathogenesis of GCT is yet poorly understood. Connexin 43 (Cx43) is the most broadly expr...
Kristin J Rybski,Hatice B Zengin,Bruce R Smoller
Kristin J Rybski
The trichorhinophalangeal syndrome type 1 (TRPS1) immunohistochemical (IHC) stain has increased in use in recent years as a marker for breast carcinomas. The TRPS1 gene is involved in various tissues, including the growth and differentiatio...
Senotherapeutic Effect of Retinaldehyde and Hyaluronate Fragments in Dermatoporosis [0.03%]
视网膜醛和透明质酸片段在皮肤老化中的细胞衰老治疗作用研究
Aysin Kaya,Jean-Hilaire Saurat,Gürkan Kaya
Aysin Kaya
Cellular senescence is one of the important mechanisms of skin aging. In a recent study, we have shown that in patients with dermatoporosis, an extreme senescence condition of the skin, cells positive for p16Ink4a, a biomarker of senescence...