Photothermal oxidative dehydrogenation of propane to propylene over Cu/BN catalysts [0.03%]
铜/氮化硼催化剂上丙烷选择性脱氢制丙烯反应研究
Shaoyuan Sun,Manqi Zhao,Huimin Liu et al.
Shaoyuan Sun et al.
Oxidative dehydrogenation of propane (ODHP) is a reaction with significant practical significance. As for the industrial application of ODHP, it is challenging to achieve high activity and high propylene selectivity simultaneously. In this ...
BAR502/fibrate conjugates: synthesis, biological evaluation and metabolic profile [0.03%]
BAR502/纤维酸缀合物：合成、生物评估和代谢谱分析
Claudia Finamore,Simona De Marino,Chiara Cassiano et al.
Claudia Finamore et al.
BAR502, a bile acid analogue, is active as dual FXR/GPBAR1 agonist and represents a promising lead for the treatment of cholestasis and NASH. In this paper we report the synthesis and the biological evaluation of a library of hybrid compoun...
Cheminformatics-based identification of phosphorylated RET tyrosine kinase inhibitors for human cancer [0.03%]
基于化学信息学的磷酸化RET酪氨酸激酶抑制剂的人类癌症鉴定方法
Md Enamul Kabir Talukder,Md Aktaruzzaman,Noimul Hasan Siddiquee et al.
Md Enamul Kabir Talukder et al.
Background: Rearranged during transfection (RET), an oncogenic protein, is associated with various cancers, including non-small-cell lung cancer (NSCLC), papillary thyroid cancer (PTC), pancreatic cancer, medullary thyroi...
Exploring essential oil-based bio-composites: molecular docking and in vitro analysis for oral bacterial biofilm inhibition [0.03%]
基于精油的生物复合材料的研究：口腔细菌生物膜抑制的分子对接和体外分析
Niamat Ullah,Syed Zia Ul Hasnain,Rabia Baloch et al.
Niamat Ullah et al.
Oral bacterial biofilms are the main reason for the progression of resistance to antimicrobial agents that may lead to severe conditions, including periodontitis and gingivitis. Essential oil-based nanocomposites can be a promising treatmen...
Extracellular vesicles enhance the in vivo antitumor effects of millettia species-derived compounds in chronic myelogenous leukemia therapy [0.03%]
外泌体可增强满山红衍生物抗慢性髓系白血病的体内疗效
Zongzhou Xie,Xiaozhen Cheng,JianCang Mao et al.
Zongzhou Xie et al.
Several Millettia species are being investigated as medicinal ingredients due to their promising anti-cancer and anti-inflammatory properties. However, the application of Millettia species-derived compounds has been severely hindered by the...
Screening factors to affect ultrasound-assisted extraction of (poly)phenols from date palm seeds [0.03%]
超声辅助提取枣核中（ poly ）酚类物质的影响因素及筛选条件研究
Raquel Lucas-González,Manuel Viuda-Martos,José Ángel Pérez-Álvarez et al.
Raquel Lucas-González et al.
The aim of the current work was to compare the (poly)phenol profile (free, soluble-conjugate, and insoluble-bound) and antioxidant activity of date palm seed flour using different extraction methods (conventional vs. ultrasound-assisted ext...
Synthesis, characterization, and anti-cancer potential of novel p53-mediated Mdm2 and Pirh2 modulators: an integrated In silico and In vitro approach [0.03%]
新型p53介导的Mdm2和Pirh2调节剂的合成，表征及抗肿瘤潜力：一种集成式的体内外研究方法
Sarfaraj Niazi,C P Kavana,H K Aishwarya et al.
Sarfaraj Niazi et al.
Introduction: Leukemia is a global health concern that requires alternative treatments due to the limitations of the FDA-approved drugs. Our focus is on p53, a crucial tumor suppressor that regulates cell division. It appears possible to st...
Post-translational activation of the C-terminus of polypeptides for the synthesis of peptide thioesters and peptide thioester surrogates [0.03%]
多肽C末端的蛋白酶活化用于合成肽硫酯及肽硫酯衍生物
Yanbo Liu,Yasuhiro Kajihara,Ryo Okamoto
Yanbo Liu
Semisynthesis using recombinant polypeptides is a powerful approach for the synthesis of proteins having a variety of modifications. Peptide thioesters, of which the peptide C-terminus is activated by a thioester, are utilized for coupling ...
Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators [0.03%]
一种通用的[68Ga]Ga-FAPI-46自动化合成方法，适用于锗-68/镓-68发电机的多级洗脱
Louis-Paul Paty,Simon Degueldre,Claire Provost et al.
Louis-Paul Paty et al.
Gallium-68-labeled FAPI-46 has recently been proposed as a novel positron emission tomography imaging probe to diagnose and monitor a wide variety of cancers. Promising results from several ongoing clinical trials have led to a soaring dema...
Comprehensive analysis of bioactive compounds in Crocus sativus stamens extracts by HPLC-DAD: investigating antidiabetic activity via in vitro, in vivo, and molecular docking simulation [0.03%]
基于HPLC-DAD的藏红花雄蕊中生物活性化合物的全面分析及其体内外抗糖尿病作用及分子对接模拟研究
Samira Mamri,Nour Elhouda Daoudi,Abedellah Baraich et al.
Samira Mamri et al.
Introduction: Medicinal herbs used in traditional diabetes treatment are a rich source of anti-diabetic compounds. Pancreatic α-amylase inhibitors offer an effective strategy to reduce postprandial hyperglycemic levels via control of starc...