AI-driven drug reposition for pathogens: a new paradigm in pandemic preparedness [0.03%]
人工智能驱动的药物再定位以应对病原体：大流行防范的新范式
Lixuan Ma,Jingshu Zhao,Junwen Luan et al.
Lixuan Ma et al.
Faced with a severe outbreak of diseases caused by newly emerging and recurrent pathogens, the development cycle of traditional drugs is long, making it difficult to meet emergency needs. Drug repositioning has become a key strategy for rap...
Artificial intelligence driven microalgae based green fabrication and bioenergy systems for sustainable energy materials and biowaste valorization [0.03%]
人工智能驱动的微藻基绿色制备和生物能源系统用于可持续能源材料和生物废物高值化
Mohaddeseh Abbaszadeh,Sai Kumar Punna,Suvarshitha Pusuluru et al.
Mohaddeseh Abbaszadeh et al.
In recent years, the bioenergy domain has experienced substantial advancement, largely driven by the integration of advanced technologies such as artificial intelligence (AI) and machine learning (ML), particularly in optimizing microalgae-...
Linking phytochemistry to bioactivity: in vitro, in vivo, and in silico insights into Rubia tinctorum [0.03%]
植物化学与生物活性的关系：通过体外、体内和计算机辅助手段研究Rubia tinctorum的化学成分与生物活性之间的联系
Fatima Zahra Ayyad,Mouad Lahyaoui,Mohammed Al-Zharani et al.
Fatima Zahra Ayyad et al.
Introduction: This study investigated the phytochemical composition and biological activities of the aqueous root extract of Rubia tinctorum L. using in vitro, in vivo, and in silico approaches. ...
Design of dual-effect molecules based on lysosome-targeting strategy: a mechanistic study on synergistic inhibition of ewing sarcoma and coronaviruses [0.03%]
基于溶酶体靶向策略的双效分子设计：Ewings肉瘤和冠状病毒协同抑制的机制研究
Shimeng Zhou,Lu Xu,Wenlong Ge
Shimeng Zhou
Introduction: Addressing clinical challenges such as the toxicity of conventional chemotherapy and viral drug resistance, this study proposes and validates an innovative "host organelle-targeting" strategy. By disrupting ...
Bis-GO@SiO2@[(CH2)3Im][Cl] nanocatalyst: a mild, reusable, and sustainable multicomponent platform for the synthesis of 2-thioarylbenzoazoles [0.03%]
双GO@SiO2@[(CH2)3Im][Cl]纳米催化剂：温和、可重复使用且可持续的多组分平台，用于合成2-硫代芳基苯并异唑类化合物
Yongshan Fu
Yongshan Fu
The development of efficient and environmentally friendly catalytic systems for making sulfur-containing heterocycles remains an important goal in synthetic chemistry. Here we describe a new hybrid nanocatalyst, Bis-GO@SiO2@[(CH2)3Im][Cl], ...
Promising multifunctional van der waals heterostructure Ti2CO2/HfSi2N4 for photovoltaics and photocatalytic OER [0.03%]
用于光伏和光催化OER的多功能范德华异质结Ti₂CO₂/HfSi₂N₄
Umair Mumtaz,Yi Ding,Ibrahim Khan et al.
Umair Mumtaz et al.
This report presents an in-depth investigation of four stacking configurations of the van der Waals heterostructure (vdW-HS) of Ti2CO2 and HfSi2N4, conducted to explore their potential for green energy applications. The vdW-HS Ti2CO2/HfSi2N...
Acid-mediated extraction of gelatine from chicken by-products: impact on yield, molecular characteristics, and structural-thermal properties [0.03%]
基于酸的明胶提取工艺及其对鸡副产品中胶原蛋白性质的影响研究
Omaima Aidat,Mohamad Khairi Zainol,Ilham Ben Amor et al.
Omaima Aidat et al.
Despite the growing interest in utilizing poultry processing by-products as sustainable sources of gelatine, the influence of extraction conditions on gelatine quality, structure, and functionality remains insufficiently understood. This st...
Lu Huang,Jean-Pierre Djukic
Lu Huang
Spin crossover (SCO) is a well-established phenomenon by which transition-metal complexes can reversibly switch between low- and high-spin states, a phenomenon widely studied in materials chemistry. Recently, transition metal complexes that...
Face reverse degree topological analysis of TP-COFs, existence of isentropic COFs and spectral characteristics [0.03%]
TP-COFs的面部反向拓扑分析及等熵COF的存在与光谱性质研究
Thirsha Rajendran,Micheal Arockiaraj,Arul Jeya Shalini et al.
Thirsha Rajendran et al.
The recent synthesis of triple-pore covalent organic frameworks (TP-COFs), specifically TP-COF-DAB and TP-COF-BZ, represents a significant milestone in framework chemistry, as replicating such multi-pore architectures remains highly challen...
An integrated annotation strategy for the phytochemical characterization of Xie-Bai-San decoction based on UPLC-Q Exactive Orbitrap HRMS, multi-database screening, and feature-based molecular networking [0.03%]
基于UPLC-Q Exactive Orbitrap高分辨质谱、多数据库筛选及特征分子网络的解白散汤植物化学表征综合注释策略
Hongjiao Chen,Kun Zhang,Yujiao Huang et al.
Hongjiao Chen et al.
Introduction: Characterizing plant-derived compounds in complex botanical formulations remains challenging because of matrix complexity, structurally related analogues, and frequent isomerism. Xie-Bai-San decoction (XBSD)...