Exploring the central region of amylin and its analogs aggregation: the influence of metal ions and residue substitutions [0.03%]
胰岛素淀粉样多肽及其类似物寡聚毒性的金属离子效应及氨基酸修饰研究
Mawadda Alghrably,Giulia Bennici,Gabriela Szczupaj et al.
Mawadda Alghrably et al.
Human amylin (hIAPP) is found in the form of amyloid deposits within the pancreatic cells of nearly all patients diagnosed with type 2 diabetes mellitus (T2DM). However, rat amylin (rIAPP) and pramlintide - hIAPP analogs - are both non-toxi...
Chia seed-mediated fabrication of ZnO/Ag/Ag2O nanocomposites: structural, antioxidant, anticancer, and wound healing studies [0.03%]
基于奇亚籽的ZnO/Ag/Ag2O纳米复合材料制备：结构、抗氧化性、抗肿瘤和促伤口愈合性能研究
Aisha Rafique,Fatima Amjad,Muhammad Ramzan Saeed Ashraf Janjua et al.
Aisha Rafique et al.
Plant extract-mediated fabrication of metal nanocomposites is used in cell proliferation inhibition and topical wound treatment, demonstrating significant effectiveness. Salvia hispanica L. (chia) seed extract (CE) is used as the reaction m...
A critical review of test methods and alternative scientific approaches to compliance and safety evaluation of paper and board for food contact [0.03%]
纸和纸板接触食品的安全性和合规性评估的标准检测方法及替代科学方案的批判性评价
Angela Störmer,Lisa Hetzel,Roland Franz
Angela Störmer
Paper and board are widely used as food contact materials. For such sensitive applications, consumer safety regarding the transfer of chemical components and contaminants to the food needs to be established. Such safety assessments are beco...
N α -acetyl-L-ornithine deacetylase from Escherichia coli and a ninhydrin-based assay to enable inhibitor identification [0.03%]
基于尼罗蓝的测定法筛选N-乙酰化L-鸟氨酸脱乙酰酶抑制剂及大肠杆菌中该酶的克隆表达与鉴定
Emma H Kelley,Jerzy Osipiuk,Malgorzata Korbas et al.
Emma H Kelley et al.
Bacteria are becoming increasingly resistant to antibiotics, therefore there is an urgent need for new classes of antibiotics to fight antibiotic resistance. Mammals do not express N ɑ -acetyl-L-ornithine deacetylase (ArgE), an enzyme that...
Harnessing biological synthesis: Zinc oxide nanoparticles for plant biotic stress management [0.03%]
生物合成的利用：用于植物生物胁迫管理的氧化锌纳米粒子
Naveen Verma,Priya Kaushal,Amanpreet K Sidhu
Naveen Verma
Crop growth and yield are negatively impacted by increased biotic stress in the agricultural sector due to increasing global warming and changing climatic patterns. The host plant's machinery is exploited by biotic stress, which is caused b...
Exploring the impact of encapsulation on the stability and bioactivity of peptides extracted from botanical sources: trends and opportunities [0.03%]
植物源肽的稳定性与生物活性受包封影响的研究：趋势与机遇探讨
Viridiana Pérez-Pérez,Cristian Jiménez-Martínez,Jorge Luis González-Escobar et al.
Viridiana Pérez-Pérez et al.
Bioactive peptides derived from plant sources have gained significant attention for their potential use in preventing and treating chronic degenerative diseases. However, the efficacy of these peptides depends on their bioaccessibility, bio...
Near-infrared spectroscopy and multivariate analysis as effective, fast, and cost-effective methods to discriminate Candida auris from Candida haemulonii [0.03%]
近红外光谱和多变量分析可有效、快速且经济地将耳念珠菌与热带念珠菌区分开来
Ayrton L F Nascimento,Anthony G J de Medeiros,Ana C O Neves et al.
Ayrton L F Nascimento et al.
Candida auris and Candida haemulonii are two emerging opportunistic pathogens that have caused an increase in clinical cases in the recent years worldwide. The differentiation of some Candida species is highly laborious, difficult, costly, ...
Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter [0.03%]
通过GABA受体和人类血清素转运蛋白探讨蛇麻叶（Humulus lupulus）中天然分子的镇静特性作为有前景的天然抗焦虑剂
Amany Belal,Mohammed S Elballal,Ahmed A Al-Karmalawy et al.
Amany Belal et al.
This research work aimed to identify the main components that are responsible for the sedative properties of hop cones and allocate their targets. This investigation was performed through molecular docking, molecular dynamic simulations, ro...
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates [0.03%]
一种绿色的heck反应制备三取代烯烃（药物合成中间体）的新方法
Giacomo Rossino,Giorgio Marrubini,Margherita Brindisi et al.
Giacomo Rossino et al.
The Heck reaction is widely employed to build a variety of biologically relevant scaffolds and has been successfully implemented in the production of active pharmaceutical ingredients (APIs). Typically, the reaction with terminal alkenes gi...
Clara S B Gomes,Alessandro Contini,Alessandro Pratesi et al.
Clara S B Gomes et al.