Editorial: Applications and advances of carbon-based materials in electrochemistry [0.03%]
电化学领域碳基材料的应用与进展评述
Min Cui,Ping Li,Yang Liu et al.
Min Cui et al.
Entropy estimation in acetylcholinesterase-donepezil interaction through topological indices: a graph theoretical perspective [0.03%]
基于拓扑指数的乙酰胆碱酯酶与多奈哌齐相互作用的熵估计：图论视角
K B Gayathri,S Roy,K Jyothish
K B Gayathri
In this work, we investigate the molecular interaction between acetylcholinesterase (AChE) and the Alzheimer's medication donepezil using a graph-theoretical approach. We have presented the molecular graphs of AChE, donepezil, and their doc...
QSPR analysis of the drugs used to treat major depressive disorder using degree and neighborhood degree based indices [0.03%]
基于度和邻居度指标的重大抑郁症用药的QSPR分析
J J Jeni Godlin,S Radha
J J Jeni Godlin
Introduction: The high risk of suicide among major depressive disorder (MDD) patients, together with its substantial contribution to the global burden of disease, emphasizes the necessity of effective drug evaluation stra...
Artificial intelligence-based modeling and validation for prediction of drug delivery capacity and cytotoxicity in design of porous materials [0.03%]
基于人工智能的模拟与验证在多孔材料药物传递能力及细胞毒性的预测中的应用研究
Sameer Alshehri,Mahboubeh Pishnamazi
Sameer Alshehri
Metal organic frameworks (MOFs) have attracted attention for application of drug delivery because of their ordered porous properties. Optimizing both drug loading capacity and biocompatibility remains a complex challenge for MOFs because th...
Peiran Liao,Peng Chen,Dan Xu et al.
Peiran Liao et al.
In search of the perfect conditions for Suzuki-Miyaura cross-couplings [0.03%]
探寻 Suzuki-Miyaura 缺电子交叉偶联反应的最佳条件
Bruce H Lipshutz,Erfan Oftadeh,Marco Ortiz
Bruce H Lipshutz
Developments in Suzuki-Miyaura (SM) couplings are discussed from a historical standpoint as they are especially valued C-C bond-forming reactions in the fine chemicals industry today. However, discussion from the increasingly important stan...
Trypanosomatid parasites, translational research in a One Health, One World environment [0.03%]
莱isin属寄生虫的转化研究：同一个健康、同一个世界环境中的研究
Alicia Ponte-Sucre
Alicia Ponte-Sucre
Adequate policies to achieve universal access to high-quality diagnostics and therapeutics in the challenge represented by Trypanosomatidae-borne diseases remain essential to command surveillance as a successful tool and a way to delay the ...
Design, synthesis, and biological evaluation of derivatives from p-toluic hydrazide: lead compound C17 exhibits membrane-disrupting and anti-biofilm activities against Staphylococcus aureus and other gram-positive bacteria [0.03%]
对p-甲基苯乙酸肼衍生物的设计、合成与生物学评价：先导化合物C17表现出对抗金黄色葡萄球菌和其他革兰氏阳性菌的膜扰动和抗生物被膜活性
Yaguang Liu,Lianzhi Hu,Binbin Liu et al.
Yaguang Liu et al.
Introduction: Bacterial drug resistance and biofilm-associated infections pose major therapeutic challenges. Schiff base derivatives have attracted attention as potential antimicrobial agents. This study aimed to design a...
Integrative characterization of Huachansu against hepatocellular carcinoma: chemical profiling, Network pharmacology, and in vivo evidence of apoptosis and gut microbiota remodeling [0.03%]
华蟾素抗肝癌的整体评价：化学谱效分析、网络药理预测及体内实验证据
Jinghui Zhang,Yang Chen,Zhuoling An et al.
Jinghui Zhang et al.
Background: Hepatocellular carcinoma (HCC) remains a major global health burden, and traditional Chinese medicine (TCM) offers complementary therapeutic advantages. Although Huachansu (HCS), a clinically used TCM preparat...
Porosity in electrochemical energy storage materials for superior performance gaining: insight into property performance and looking ahead [0.03%]
电化学储能材料中的孔隙度：实现优异性能的见解、属性与展望
Pan Shulin,Walid Tahri,Amani Khaskhoussi et al.
Pan Shulin et al.
The use of renewable energy, electric vehicles, and high-density compact devices requires the power density, long-term stability, and long cycle life of the electrochemical energy storage (ESS) systems. Ion transport, charge storage and mec...