Long-Term Treatment with Bulevirtide in Patients with Chronic Hepatitis D and Advanced Chronic Liver Disease [0.03%]
慢性乙肝和失代偿性肝病患者长期使用布拉西汀治疗
Ayaz Sapuk,Leonie Steinhoff,Kristin Huenninghaus et al.
Ayaz Sapuk et al.
Bulevirtide (BLV) is approved for the treatment of chronic hepatitis D (CHD). Because only limited long-term experience has been reported, we aimed to evaluate the efficacy and safety of BLV treatment in patients with advanced chronic liver...
Wulingsan Alleviates MAFLD by Activating Autophagy via Regulating the AMPK/mTOR/ULK1 Signaling Pathway [0.03%]
五岭山通过调节AMPK/mTOR/ULK1信号通路激活自噬缓解MAFLD
Yaning Biao,Dantong Li,Yixin Zhang et al.
Yaning Biao et al.
Here, we presented the study of the molecular mechanisms underlying the action of Wulingsan (WLS) in rats with metabolic-associated fatty liver disease (MAFLD) induced by a high-fat diet (HFD). High-performance liquid chromatography was emp...
Lobe-Based Hepatic Uptake Index of Gd-EOB-DTPA on Contrast-Enhanced MRI to Quantitatively Discriminate between Compensated and Decompensated Hepatitis B-Related Cirrhosis [0.03%]
基于肝叶的Gd-EOB-DTPA肝摄取指数定量鉴别乙肝相关肝硬化代偿期与失代偿期的对比增强MRI研究
Fulin Lu,Bangguo Tan,Yucheng Huang et al.
Fulin Lu et al.
Purpose: To use hepatic uptake index (HUI) of liver lobes on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) to discriminate between patients with hepati...
Clinical Outcomes of Ileostomy Closure during versus after Adjuvant Chemotherapy in Patients with Rectal Cancer [0.03%]
结肠癌患者术前新辅助化疗与术后即刻闭合回肠造口的临床效果研究
Fan He,Fuyu Yang,Chenglin Tang et al.
Fan He et al.
Background: Protective ileostomy can effectively prevent severe anastomotic leakage after rectal cancer surgery; however, the optimal timing for ileostomy closure during adjuvant chemotherapy remains unclear. This study a...
A Meta-Analysis of MiRNA-497 and Prognosis of Hepatocellular Carcinoma [0.03%]
miRNA-497的表达与肝细胞癌预后关系的meta分析研究
Zhiqiang Xie,Qingzhi Hao,Rongrong Zhu et al.
Zhiqiang Xie et al.
Background: Recently, microRNA-497 (miR-497) has been reported as a prognostic marker for hepatocellular carcinoma (HCC). However, there is no systematic study summarizing these data. Herein, we elucidated the prognostic ...
The Role of Inflammatory Biomarkers in Mediating the Effect of Inflammatory Bowel Disease on nonmalignant Digestive System Diseases: A Multivariable Mendelian Randomized Study [0.03%]
基于多变量孟德尔随机化研究的炎症性肠病相关炎性生物标志物与非恶性消化系统疾病的关系研究
Shu Zhou,Qi Sun,Ning Gao et al.
Shu Zhou et al.
Background: While observation studies have shown a positive correlation between inflammatory bowel disease (IBD) and the risk of nonmalignant digestive system diseases, a definitive causal relationship has not yet been cl...
Hepatitis C Virus Infection and Hospital-Related Outcomes: A Systematic Review [0.03%]
丙型肝炎病毒感染与住院相关结果：系统性回顾
Michelle Ng,Patrizia Maria Carrieri,Lindila Awendila et al.
Michelle Ng et al.
Background: People living with hepatitis C infection (HCV) have a significant impact on the global healthcare system, with high rates of inpatient service use. Direct-acting antivirals (DAAs) have the potential to allevia...
Hepatitis C Attributable Healthcare Costs and Mortality among Immigrants: A Population-Based Matched Cohort Study [0.03%]
移民中的丙型肝炎相关医疗保健费用和死亡率：基于人群的配对队列研究
Aysegul Erman,Yeva Sahakyan,Karl Everett et al.
Aysegul Erman et al.
Background: Data on the economic burden of chronic hepatitis C (CHC) among immigrants are limited. Our objective was to estimate the CHC-attributable mortality and healthcare costs among immigrants in Ontario, Canada. ...
Prevalence of Esophageal Eosinophilia, Eosinophilic Esophagitis, and Lymphocytic Gastritis in Children with Celiac Disease: A Saudi Tertiary Center Experience [0.03%]
患有乳糜病的儿童中的食道嗜酸细胞增多症，嗜酸细胞性食管炎和淋巴细胞性胃炎的流行率：一项沙特三级诊疗中心的经验
Meshari A Alaifan,Ammar Khayat,Rana Y Bokhary et al.
Meshari A Alaifan et al.
Background: Celiac disease (CD) is an immune-mediated enteropathy that has been associated with other immune-related gastrointestinal disorders, such as eosinophilic esophagitis (EoE) and lymphocytic gastritis (LG). To ou...
Ghrelin/GHSR Axis Induced M2 Macrophage and Alleviated Intestinal Barrier Dysfunction in a Sepsis Rat Model by Inactivating E2F1/NF- κ B Signaling [0.03%]
胃饥饿素/生长激素分泌素受体诱导M2型巨噬细胞并通过失活E2F1/NF- κ B信号缓解脓毒症大鼠模型的肠道屏障功能障碍
Lei Zhu,Zhimin Dou,Wei Wu et al.
Lei Zhu et al.
Sepsis is an inflammatory reaction disorder state that is induced by infection. The activation and regulation of the immune system play an essential role in the development of sepsis. Our previous studies have shown that ghrelin ameliorates...