Non-canonical Function of Prolyl Hydroxylase Domain 2 in Breast Cancer Cell Growth and Progression: Role of Peptidyl-prolyl Cis-trans Isomerase NIMA-interacting 1 [0.03%]
脯氨酰羟化酶结构域蛋白2在乳腺癌细胞生长和进展中的非经典功能：肽基-脯氨酸顺反异构酶NIMA相互作用蛋白1的作用
Yanymee N Guillen-Quispe,Su-Jung Kim,Soma Saeidi et al.
Yanymee N Guillen-Quispe et al.
Prolyl hydroxylase domain 2 (PHD2) is the primary oxygen sensing enzyme involved in hydroxylation of hypoxia-inducible factor (HIF). Under normoxic conditions, PHD2 hydroxylates specific proline residues in HIF-1α and HIF-2α, promoting th...
Identification of Translocon-associated Protein Delta as An Oncogene in Human Colorectal Cancer Cells [0.03%]
鉴定出拓扑大链连接蛋白delta为人类结直肠癌细胞的原癌基因
Darshika Amarakoon,Wu-Joo Lee,Jing Peng et al.
Darshika Amarakoon et al.
Identifying the roles of genes in cancer is critical in discovering potential genetic therapies for cancer care. Translocon-associated protein delta (TRAPδ), also known as signal sequence receptor 4 (SSR4), is a constituent unit in the TRA...
Relationship between Cancer Incidence and Health Behaviors from Ecological Study in Korea [0.03%]
基于生态学研究的韩国癌症发病与健康行为的关系分析
Kwang-Pil Ko
Kwang-Pil Ko
The aim of this ecological study was to examine the correlation between cancer incidence and health behaviors such as smoking, alcohol consumption, and obesity, and investigated whether there were differences in this correlation between met...
Kelch-like ECH-associated Protein 1/Nuclear Factor Erythroid 2-related Factor 2 Pathway and Its Interplay with Oncogenes in Lung Tumorigenesis [0.03%]
Kelch样ECH相关蛋白1/核因子E2相关因子2通路及其与癌基因在肺癌发生中的互作关系
Taegeun Bae,Mi-Kyoung Kwak
Taegeun Bae
Nuclear factor erythroid 2-related factor 2 (NRF2), a transcription factor regulating cellular redox homeostasis, exhibits a complex role in cancer biology. Genetic mutations in the Kelch-like ECH-associated protein 1 (KEAP1)/NRF2 system, w...
Challenges in Metabolite Biomarkers as Avenues of Diagnosis and Prognosis of Cancer [0.03%]
代谢标志物在癌症诊断和预后中的挑战与机遇
Nilesh Kumar Sharma,Sachin C Sarode,Gopinath Sekar et al.
Nilesh Kumar Sharma et al.
Given the evolutionary nature of tumor complexities and heterogeneity, the early diagnosis of cancer encounters various challenges. Complexities at the level of metabolite reprogramming are compelling in the background of invasiveness, meta...
Anticancer Activity of Phytochemicals of the Papaya Plant Assessed: A Narrative Review [0.03%]
番木瓜植物的药用活性评估：叙述性综述
Shachi Patel,Karankumar Rana,Param Arya et al.
Shachi Patel et al.
Cancer remains to be a pervasive disease as traditional treatments have plateaued in efficacy. Anticancer research continues to grow in an effort to find novel preventive and treatment measures for cancers. The papaya plant produces several...
Kaempferol Synergistically Enhances Cisplatin-induced Apoptosis and Cell Cycle Arrest in Colon Cancer Cells [0.03%]
kaempferol通过协同增强顺铂诱导的凋亡和细胞周期阻滞来抑制结肠癌细胞生长
Muhammad Haroon,Sun Chul Kang
Muhammad Haroon
Colon cancer remains a significant global health concern, necessitating the continuous exploration of novel therapeutic strategies. Cisplatin is a first-line chemotherapy medication that is frequently used to treat patients for a variety of...
Recommendations for Healthy Lifestyle for Cancer Prevention and Healthy Aging [0.03%]
癌症预防和健康老龄化的健康生活方式推荐
Omer Kucuk,Viraj A Master
Omer Kucuk
Ribosomal Protein L9 Maintains Stemness of Colorectal Cancer via an ID-1 Dependent Mechanism [0.03%]
核糖体蛋白L9通过ID-1依赖机制维持结直肠癌干细胞特性
Eun-Hye Jeon,So-Young Park,Keon Uk Park et al.
Eun-Hye Jeon et al.
The identification of therapeutic target genes that are functionally involved in stemness is crucial to effectively cure patients with metastatic carcinoma. We have previously reported that inhibition of ribosomal protein L9 (RPL9) expressi...
Elevated N1-Acetylspermidine Levels in Doxorubicin-treated MCF-7 Cancer Cells: Histone Deacetylase 10 Inhibition with an N1-Acetylspermidine Mimetic [0.03%]
依托泊苷治疗的MCF-7癌细胞中N1-乙酰精胺水平升高：使用N1-乙酰精胺类似物抑制组蛋白去乙酰化酶10
Ajay Kumar Raj,Kiran Bharat Lokhande,Kratika Khunteta et al.
Ajay Kumar Raj et al.
Cancer drug resistance is associated with metabolic adaptation. Cancer cells have been shown to implicate acetylated polyamines in adaptations during cell death. However, exploring the mimetic of acetylated polyamines as a potential antican...