Oral Administration of Withaferin A Increases Infiltration of CD4+ Helper T Cells in a Mouse Model of Mammary Tumor [0.03%]
口服毛蕊香脂A可增加乳腺肿瘤小鼠模型中CD4⁺辅助T细胞的浸润
Eun-Ryeong Hahm,Krishna B Singh,Shivendra V Singh
Eun-Ryeong Hahm
Withaferin A (WA) is a small molecule present in Ashwagandha plant that prevents breast cancer progression in mice and rats. The mechanisms underlying breast cancer prevention by WA are not fully understood. Herein, we report effects of WA ...
Establishment of a Gastric Cancer Diagnostic Model Based on the Combined Evaluation of Peripheral Blood Immune-inflammatory Nutritional Indicators and Tumor Markers [0.03%]
基于外周血免疫炎症营养指标联合肿瘤标志物建立胃癌诊断模型
Ke Chen,Jinglue Han,Xiaoxue Zhang et al.
Ke Chen et al.
This study aimed to develop a non-invasive diagnostic model for gastric cancer (GC) by combining serum immune-inflammatory-nutrition indicators with traditional tumor markers to improve early diagnosis efficiency. Our retrospective analysis...
Ginseng Tea Consumption and Liver Cancer Risk: A Prospective Korean Multi-center Cancer Cohort Study [0.03%]
人参茶消费与肝癌风险的相关性：一项韩国多中心癌症队列研究
Sungji Moon,Soseul Sung,Sangjun Lee et al.
Sungji Moon et al.
Ginseng has been widely consumed for its purported chemoprotective effects against various disease including cancer. However, the association between ginseng tea consumption and liver cancer (LC) risk remains unclear, particularly among ind...
Differences in Self-purchased Complementary and Alternative Medicine Use and Patient-reported Satisfaction between Female-specific and Non-female-specific Cancer Patients [0.03%]
性别特定与非性别特异性癌症患者的自购补充和替代医学使用及患者报告的满意度差异
Aelee Jang
Aelee Jang
This study aimed to investigate demographic and clinical factors associated with use of complementary and alternative medicine (CAM) and to compare CAM utilization patterns, including self-purchase behaviors and patient-reported satisfactio...
Advances in T-Lymphokine-activated Killer Cell-originated Protein Kinase Research in Cancer Over the Past Thirty Years [0.03%]
过去三十年肿瘤TLAK蛋白激酶研究进展
Mengyu Zhao,Ran Zhao,Zigang Dong et al.
Mengyu Zhao et al.
Nearly thirty years ago, T-lymphokine-activated killer (T-LAK) cell-originated protein kinase (TOPK), also known as PDZ-binding kinase, was first identified as a serine/threonine kinase with limited known functions. Over time, this molecule...
Truncating Adenomatous Polyposis Coli Mutations Serve as a Biomarker for Advanced Tumor Stage in Iranian Patients with Familial Colorectal Cancer [0.03%]
截短型腺瘤性结肠息肉病突变可作为伊朗家族性结直肠癌患者晚期肿瘤阶段的生物标志物
Ali Zarei,Abolfazl Khalafi-Nezhad,Sara Senemar et al.
Ali Zarei et al.
The Adenomatous Polyposis Coli gene (APC) is a key tumor suppressor in colorectal cancer (CRC). While germline mutations in its Mutation Cluster Region (MCR) are implicated in familial CRC, the prognostic impact of specific mutation types w...
Hepatocellular Carcinoma Over Three Decades: from Screening Evolution to Integrated Therapeutic Strategies [0.03%]
三十年来的肝细胞癌：从筛查演变至综合治疗策略
Ke Huang,Myoung Ok Kim
Ke Huang
Hepatocellular carcinoma (HCC) continues to impose a substantial global health burden, with the incidence and the mortality remaining closely aligned despite major advances in diagnostics and therapeutics. Over the past three decades, scree...
The Immunoregulatory Roles of ERα in Breast Cancer: Mechanisms, Crosstalk, and Therapeutic Insights [0.03%]
雌激素受体α在乳腺癌中的免疫调节作用：机制、相互作用和治疗启示
Afsoon Dehghani
Afsoon Dehghani
Estrogen receptor alpha (ERα) defines the biology of estrogen receptor-positive breast cancer by regulating both tumor-intrinsic signaling and the surrounding immune microenvironment. Beyond its genomic and non-genomic actions, ERα modula...
Ethnic Heterogeneity in Reproductive Risk Factors for Breast Cancer, With a Focus on Asian Populations: A Meta-analysis [0.03%]
聚焦亚洲人群的乳腺癌生殖危险因素的种族异质性meta分析研究
Youjin Hong,Soseul Sung,Woojin Lim et al.
Youjin Hong et al.
This study aimed to examine differences in the association between reproductive factors and breast cancer (BC) risk across ethnic groups, particularly Asians and non-Asians, and to explore temporal trends through meta-analysis. The study fo...
Methionine Intake, Dietary Acid Load, and Breast Cancer Risk: A Case-control Study [0.03%]
蛋氨酸摄入量、膳食酸负荷与乳腺癌风险：一项病例对照研究
Alvaro L Ronco,Wilner Martínez-López,Maximilian A Storz
Alvaro L Ronco
Limited epidemiologic evidence links cancer risk to dietary acid load and methionine intake. Acid stress and metabolic acidosis are closely related to cancer development. Methionine is the main acidogenic amino acid and exerts epigenetic in...