Patterns of Oncological Clinical Trials in African Countries: A Scoping Review [0.03%]
非洲国家肿瘤临床试验模式综述
Kumban Walter Chuck,Tung Hoang,Jeongseon Kim
Kumban Walter Chuck
Africa has increasingly participated in clinical trials; however, there is limited literature on the trends of oncological clinical trial registration. This study aims to review the patterns of oncological clinical trials conducted in Afric...
The Role of Mesenchymal Stem Cells in Drug Resistance in Lung Neoplasms [0.03%]
间充质干细胞在肺肿瘤耐药中作用机制的研究进展
Dongho Kang,Eunhee Yeon,Sunyoung Kim et al.
Dongho Kang et al.
The tumor microenvironment (TME) is a decisive determinant of therapeutic response and the emergence of drug resistance in lung cancer. Among its stromal constituents, mesenchymal stem cells (MSCs) are pivotal regulators of disease progress...
Comparative Analysis of Aging-related Metabolic and Biological Markers between Cancer Survivors and Healthy Populations: A Systematic Review [0.03%]
癌症幸存者与健康人群衰老相关代谢及生物标志物的比较分析系统评价
Nur Afifah Mursyida Zaujan,Mohd Razif Shahril,Suzana Shahar et al.
Nur Afifah Mursyida Zaujan et al.
Cancer survivors may exhibit biological and metabolic changes linked to both cancer and its treatment. This systematic review aimed to compare metabolic and biological aging-related biomarkers between cancer survivors and healthy individual...
Development of Primary Colon and Duodenal Tumor Cultures from the Apc-mutant Pirc Rat for Screening Preventive Agents [0.03%]
开发Apc突变Pirc大鼠原发性结肠和十二指肠肿瘤培养物用于预防剂筛选
Ahmed Muhsin,Sultan Neja,Nivedhitha Mohan et al.
Ahmed Muhsin et al.
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality, with genetic, epigenetic, and immune-dependent mechanisms contributing to disease pathogenesis. Preventive strategies are especially important for individuals with...
Effect of Aspirin on Development of First and Recurrent Primary Cutaneous Keratinocyte Carcinomas in Older Australian Adults: Extended Follow-up of a Large Randomised Controlled Trial [0.03%]
一项大型随机试验的长期随访结果：阿司匹林对澳大利亚老年成人第一原发性皮肤鳞癌及复发的影响
Emma Hiscutt,Mabel Yan,Victoria Mar et al.
Emma Hiscutt et al.
Keratinocyte carcinomas (KC) are the most frequent cancers diagnosed in Australia and impart the largest economic cost of all cancers. Predisposed individuals tend to develop multiple KC over their lifetime. Data from the ASPirin in Reducin...
Primary and Secondary Prophylaxis for Diseases Caused by Human Papillomavirus Infections [0.03%]
人乳头瘤病毒所致疾病的一级和二级预防措施
Meri Arman Hristamyan
Meri Arman Hristamyan
Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and a leading cause of several cancers, including cervical, anal, oropharyngeal, vulvar, vaginal, and penile cancers, as well as benign conditions such a...
Sevelamer Ameliorates Early Cirrhosis and Inhibits Its Progression towards Hepatocellular Carcinoma in a Diethylnitrosamine-induced Rat Model [0.03%]
司维拉姆改善二乙基亚硝胺诱导的大鼠肝硬化模型并向逆转肝癌发展
Ze-Ning Chen,Yang-Feng Lv,Zhi-Xing Liu et al.
Ze-Ning Chen et al.
Cirrhosis has a very high morbidity and mortality and partially progressed into hepatocellular carcinoma (HCC). Sevelamer is an oral phosphate binder to treat hyperphosphatemia. Here, we investigated the contribution of sevelamer to the rem...
Fruit and Vegetable Intake in Relation to Lung Cancer Risk: A Systematic Review and Dose-response Meta-analysis of Prospective Cohort Studies [0.03%]
关于肺癌风险的水果和蔬菜摄入量的系统评价和剂量反应 meta 分析
Seyed Vahid Ahmadi Tabatabaei,Ali Akbar Haghdoost,Seyyed Mohammad Alavi et al.
Seyed Vahid Ahmadi Tabatabaei et al.
The objective of this study was to consolidate the mounting evidence related to the association between fruit and vegetable intake and lung cancer risk by conducting a systematic review of prospective studies and a dose-response meta-analys...
Esculetin Attenuates the Migration and Invasion of Human Hepatocellular Carcinoma Cells by Attenuating Matrix Metalloproteinase Activity and Strengthening Tight Junctions [0.03%]
esculetin通过减弱基质金属蛋白酶活性和增强紧密连接来削弱人类肝癌细胞的迁移和侵袭作用
Sung Ok Kim,Hyun Hwangbo,Su Hyun Hong et al.
Sung Ok Kim et al.
Hepatocellular carcinoma (HCC) is a highly malignant liver cancer that metastasizes to various organs. Esculetin, a natural dihydroxy coumarin derivative, has been shown to have a variety of pharmacological properties, including immune-enha...
Chemoprevention of Keratinocyte Cancers: Could Aspirin Be the Solution? [0.03%]
阿司匹林可能是预防角质细胞肿瘤的有效手段吗？
Emma Hiscutt,Suzanne Orchard,Rory Wolfe et al.
Emma Hiscutt et al.
Keratinocyte cancer burden is escalating, particularly in older Australian adults, where the incidence was > 6,000/100,000 in persons aged 80 to 84 per year, compared with 26/100,000 in persons aged 20 to 24 per year, in Queensland between ...