Helicobacter pylori Induces Hypermethylation of CpG Islands Through Upregulation of DNA Methyltransferase: Possible Involvement of Reactive Oxygen/Nitrogen Species [0.03%]
幽门螺杆菌通过上调DNA甲基转移酶诱导CpG岛高甲基化：活性氧/氮的可能作用
Hye-Kyung Na,Jeong-Hwa Woo
Hye-Kyung Na
Helicobacter pylori infection has been considered to be one of the major factors implicated in etiology of gastric cancer. Aberrant DNA methylation accounts for epigenetic modifications induced by H. pylori. H. pylori-induced hypermethylati...
Cancer Preventive Potential of Kimchi Lactic Acid Bacteria (Weissella cibaria, Lactobacillus plantarum) [0.03%]
kimchi乳酸菌（Weissella cibaria、Lactobacillus plantarum）的癌症预防潜力
Shin-Hye Kwak,Young-Mi Cho,Geon-Min Noh et al.
Shin-Hye Kwak et al.
The number of death due to cancer has been increasing in Korea. Chemotherapy is known to cause side effects because it damages not only cancerous cells but healthy cells. Recently, attention has focused on food-derived chemopreventive and a...
Extract of Artemisia lavandulaefolia Inhibits In Vitro Angiogenesis in Human Umbilical Vein Endothelial Cells [0.03%]
艾蒿提取物通过抑制人脐静脉内皮细胞的体外血管生成作用达到抗肿瘤效果
Eui-Yeun Yi,Kyung-Suk Han,Yung-Jin Kim
Eui-Yeun Yi
Angiogenesis is important processes for tumor growth and metastasis. Anti-angiogenesis target therapy has recently been known to be new anti-cancer therapeutic strategies. Natural products such as traditional medicine comprise a major sourc...
Obesity, Body Image, Depression, and Weight-control Behaviour Among Female University Students in Korea [0.03%]
韩国女大学生的肥胖、体像、抑郁和体重控制行为的关系研究
Eun Mi Jun,Seung Bae Choi
Eun Mi Jun
Background: Obesity has become epidemic worldwide and 31.0% of Korean adults are obese. Obesity is the main cause of chronic diseases, such as diabetes, hypertension, cardiac disease, and cancer. The purpose of the study ...
L1 cell adhesion molecule expression is associated with pelvic lymph node metastasis and advanced stage in diabetic patients with endometrial cancer: a matched case control study [0.03%]
糖尿病子宫内膜癌患者L1细胞黏附分子表达与盆腔淋巴结转移及临床分期的关系：病例对照研究
Dong Hoon Suh,Min A Kim,Hee Seung Kim et al.
Dong Hoon Suh et al.
Background: Diabetic patients with endometrial cancer had more lymph node metastasis than non-diabetic patients with endometrial cancer. L1 cell adhesion molecule (L1CAM) could be possibly associated with lymph node metas...
Histologic Findings and Inflammatory Reactions After Long-term Colonization of Helicobacter felis in C57BL/6 Mice [0.03%]
Helicobacter felis长期定植C57BL/6小鼠的病理改变及炎症反应
Ju Yup Lee,Nayoung Kim,Yoon Jeong Choi et al.
Ju Yup Lee et al.
Background: The Helicobacter felis (H. felis) mouse model has been developed for the research regarding pathogenesis of chronic gastritis and gastric cancer. The aim of this study was to investigate long-term H. felis col...
Supplementation of Seaweeds Extracts Suppresses Azoxymethane-induced Aberrant DNA Methylation in Colon and Liver of ICR Mice [0.03%]
海带提取物补充可抑制ICR小鼠体内偶氮甲烷致结肠和肝脏DNA异常甲基化作用
So Young Bu,Hoonjeong Kwon,Mi-Kyung Sung
So Young Bu
Background: Seamustard and seatangle are commonly consumed seaweeds in Korea and rich sources of non-digestible polysaccharides which possess biological activities. However anti-mutagenic and anti-cancer activities of the...
Antioxidative Activity of Blueberry Leaf Extract Prevents High-fat Diet-induced Obesity in C57BL/6 Mice [0.03%]
越橘叶提取物的抗氧化活性能防止高脂饮食诱导的C57BL/6小鼠肥胖
In-Chul Lee,Dae Yong Kim,Bu Young Choi
In-Chul Lee
Background: Health beneficial effects of blueberry have been well documented. Obesity is health hazard that is associated with metabolic abnormalities. We investigated the effect of blueberry leaf extract (BBLE) on high-f...
Fibroblast and Epidermal Growth Factors Utilize Different Signaling Pathways to Induce Anchorage-independent Cell Transformation in JB6 Cl41 Mouse Skin Epidermal Cells [0.03%]
成纤维细胞和表皮生长因子通过不同的信号途径诱导小鼠皮肤表皮JB6 Cl41细胞在无依附条件下的细胞转化
Cheol-Jung Lee,Mee-Hyun Lee,Yong-Yeon Cho
Cheol-Jung Lee
Background: Extracellular stimulation of cells with growth factors such as epidermal growth factor (EGF) induces cell proliferation and cell transformation. Although fibroblast growth factor (FGF) is a well-known family m...
The Nuclear Matrix Protein, NRP/B, Acts as a Transcriptional Repressor of E2F-mediated Transcriptional Activity [0.03%]
核基质蛋白NRP/B通过抑制E2F介导的转录活性而起转录阻遏作用
Jina Choi,Eun Sung Yang,Kiweon Cha et al.
Jina Choi et al.
Background: NRP/B, a family member of the BTB/Kelch repeat proteins, is implicated in neuronal and cancer development, as well as the regulation of oxidative stress responses in breast and brain cancer. Our previous studi...