Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer [0.03%]
萎缩性胃炎和肠上皮化生作为胃癌的癌前病变的研究进展
Yo Han Park,Nayoung Kim
Yo Han Park
Atrophic gastritis (AG) and intestinal metaplasia (IM) are the main precursor lesions of gastric cancer as the incidence of gastric cancer increases in the gastric mucosa involved with AG and IM. The prevalence of AG and IM vary depending o...
Endocrine-disrupting Chemicals: Review of Toxicological Mechanisms Using Molecular Pathway Analysis [0.03%]
内分泌干扰物毒理学机制的分子途径分析研究
Oneyeol Yang,Hye Lim Kim,Jong-Il Weon et al.
Oneyeol Yang et al.
Endocrine disruptors are known to cause harmful effects to human through various exposure routes. These chemicals mainly appear to interfere with the endocrine or hormone systems. As importantly, numerous studies have demonstrated that the ...
Small Molecule Inhibitors to Disrupt Protein-protein Interactions of Heat Shock Protein 90 Chaperone Machinery [0.03%]
用于干扰热休克蛋白90分子伴侣机器中蛋白质相互作用的小分子抑制剂
Young Ho Seo
Young Ho Seo
Heat shock protein 90 (Hsp90) is an adenosine triphosphate dependent molecular chaperone in eukaryotic cells that regulates the activation and maintenance of numerous regulatory and signaling proteins including epidermal growth factor recep...
Primary cancer prevention by green tea, and tertiary cancer prevention by the combination of green tea catechins and anticancer compounds [0.03%]
绿茶抗癌的一级预防和绿茶儿茶素与抗肿瘤化合物联合的三级预防
Hirota Fujiki,Eisaburo Sueoka,Tatsuro Watanabe et al.
Hirota Fujiki et al.
Green tea is a daily beverage, a non-oxidized non-fermented product containing at least four green tea catechins. Considering our first results when repeated applications of (-)-epigallocatechin gallate (EGCG) prevented tumor promotion in m...
The diagnostic validity of the (13)c-urea breath test in the gastrectomized patients: single tertiary center retrospective cohort study [0.03%]
胃切除患者的诊断有效性：单中心回顾性队列研究
Yong Hwan Kwon,Nayoung Kim,Ju Yup Lee et al.
Yong Hwan Kwon et al.
Background: This study was conducted to evaluate the diagnostic validity of the (13)C-urea breath test ((13)C-UBT) in the remnant stomach after partial gastrectomy for gastric cancer. ...
Aging alters hepatic DNA hydroxymethylation, as measured by liquid chromatography/mass spectrometry [0.03%]
衰老通过液相色谱/质谱法改变肝脏DNA羟甲基化水平
Stephanie A Tammen,Gregory G Dolnikowski,Lynne M Ausman et al.
Stephanie A Tammen et al.
Background: Aging is one of the most important risk factors for cancer. It appears that aberrant epigenetic changes might be a common driver of aging and cancer. Among them are changes in DNA methylation and DNA hydroxyme...
Eugenol-rich Fraction of Syzygium aromaticum (Clove) Reverses Biochemical and Histopathological Changes in Liver Cirrhosis and Inhibits Hepatic Cell Proliferation [0.03%]
Syzygium aromaticum（肉桂）中富含丁香酚的组分可逆转肝硬化生化和组织病理学变化并抑制肝细胞增殖
Shakir Ali,Ram Prasad,Amena Mahmood et al.
Shakir Ali et al.
Background: Dried flower bud of Syzygium aromaticum (clove) is rich in eugenol, an antioxidant and antiinflammatory compound that can protect liver against injury. Clove, besides eugenol, also contains other pharmacologic...
Anti-inflammatory Effects of Schisandra chinensis (Turcz.) Baill Fruit Through the Inactivation of Nuclear Factor-κB and Mitogen-activated Protein Kinases Signaling Pathways in Lipopolysaccharide-stimulated Murine Macrophages [0.03%]
五味子果实通过灭活核因子-κb和促有丝分裂原激活蛋白激酶信号途径发挥抗炎作用：机制研究
Young-Soon Kang,Min-Ho Han,Su-Hyun Hong et al.
Young-Soon Kang et al.
Background: Schisandrae Fructus, the dried fruit of Schisandra chinensis (Turcz.) Baill. (Magnoliaceae), is widely used in traditional medicine for the treatment of a number of chronic inflammatory diseases. This study ex...
Induction of Cell Cycle Arrest and Apoptosis by Physcion, an Anthraquinone Isolated From Rhubarb (Rhizomes of Rheum tanguticum), in MDA-MB-231 Human Breast Cancer Cells [0.03%]
药用大黄中的安ocalbin物理素通过诱导细胞周期停滞和MDA-MB-231人乳腺癌细胞凋亡发挥抗肿瘤作用
Ji-Young Hong,Hwa-Jin Chung,Song Yi Bae et al.
Ji-Young Hong et al.
Background: Physcion is an anthraquinone from rhubarb (rhizomes of Rheum tanguticum) and has been reported to have anti-inflammatory, hepatoprotective, antifungal, and anti-cancer activities. However, the growth inhibitor...
Pycnogenol Induces Nuclear Translocation of Apoptosis-inducing Factor and Caspase-independent Apoptosis in MC-3 Human Mucoepidermoid Carcinoma Cell Line [0.03%]
皮克宁索诱导成神经细胞凋亡因子核转位及MC-3人黏膜表皮样细胞系的天冬氨酸蛋白酶独立型细胞凋亡
In-Hyoung Yang,Ji-Ae Shin,Sung-Dae Cho
In-Hyoung Yang
Background: Pycnogenol is extracted from the pine bark of a tree known as Pinus pinaster that has variety biological effects. However, its anticancer activity has not yet been completely studied. The aim of this study is ...