Effects of β-carotene on Expression of Selected MicroRNAs, Histone Acetylation, and DNA Methylation in Colon Cancer Stem Cells [0.03%]
β-胡萝卜素对结直肠癌干细胞中选择性微小RNA表达、组蛋白乙酰化和DNA甲基化的影响
Daeun Kim,Yerin Kim,Yuri Kim
Daeun Kim
Background: Beta-carotene (BC) is a carotenoid which exerts anti-cancer effects in several types of cancer, including colorectal cancer. Epigenetic modifications of genes, such as histone deacetylation and DNA hypermethyl...
Overcoming the Intrinsic Gefitinib-resistance via Downregulation of AXL in Non-small Cell Lung Cancer [0.03%]
通过下调AXL克服非小细胞肺癌的内在吉非替尼耐药性
Inae Jeong,Jayoung Song,Song Yi Bae et al.
Inae Jeong et al.
Background: Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, is a limited factor in the treatment of non-small-cell lung cancer (NSCLC) patients. Therefore, ongoing...
Food Intake Behavior in Cancer Survivors in Comparison With Healthy General Population; From the Health Examination Center-based Cohort [0.03%]
与健康人群相比癌症幸存者的进食行为；来自健康检查中心队列的数据
Tung Hoang,Jeonghee Lee,Jeongseon Kim et al.
Tung Hoang et al.
Background: This study aimed to investigate the food intake behavior of cancer survivors based on main sources of energy intake from different food groups in comparison with healthy individuals. ...
Genistein Inhibits Proliferation of BRCA1 Mutated Breast Cancer Cells: The GPR30-Akt Axis as a Potential Target [0.03%]
染料木素通过GPR30-Akt信号轴抑制BRCA1突变的乳腺癌细胞增殖作用研究
Ga Yun Kim,Jinyoung Suh,Jeong-Hoon Jang et al.
Ga Yun Kim et al.
Background: BRCA1 mutated breast cancer cells exhibit the elevated cell proliferation and the higher metastatic potential. G protein-coupled receptor 30 (GPR30) has been shown to regulate growth of hormonally responsive c...
β-carotene Inhibits Expression of c-Myc and Cyclin E in Helicobacter pylori-infected Gastric Epithelial Cells [0.03%]
β-胡萝卜素能抑制Helicobacter pylori感染的胃粘膜上皮细胞中c-myc和cyclin e的表达
Dahye Kim,Joo Weon Lim,Hyeyoung Kim
Dahye Kim
Background: Helicobacter pylori infection is a major risk factor in the development of gastric cancer. H. pylori infection of gastric epithelial cells increases the levels of reactive oxygen species (ROS), activates oncog...
15-Deoxy-Δ12,14-prostaglandin J2 Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells [0.03%]
15-脱氧-δ12,14-前列腺素J2通过诱导活化蛋白-1激活和血红素加氧酶-1表达上调人结肠癌细胞中15-羟基前列腺素脱氢酶的表达
Jong-Min Park,Hye-Kyung Na
Jong-Min Park
Background: Abnormal upregulation of prostaglandin E2 (PGE2) is considered to be a key oncogenic event in the development and progression of inflammation-associated human colon cancer. It has been reported that 15-hydroxy...
Sex-related Alterations of Gut Microbiota in the C57BL/6 Mouse Model of Inflammatory Bowel Disease [0.03%]
在C57BL/6鼠炎症性肠病模型中观察到肠道菌群的性别二态性
Hee Jin Son,Nayoung Kim,Chin-Hee Song et al.
Hee Jin Son et al.
Background: Gut microbiota is closely associated with development and exacerbation of inflammatory bowel diseases (IBD). The aim of this study was to investigate differences in gut microbiota depending on sex and changes ...
Samrawit Solomon,Wudeneh Mulugeta
Samrawit Solomon
Background: Cancer is one of the leading causes of morbidity and mortality worldwide. Yet, limited is known about patterns of cancer and risk factors for advanced stage cancers in Ethiopia. ...
Involvement of Up-regulation of Death Receptors and Bim in Hispolon-mediated TNF-related Apoptosis-inducing Ligand Sensitization in Human Renal Carcinoma [0.03%]
Hispolon通过上调死亡受体和Bim介导的TRAIL依赖的细胞凋亡促进人肾癌细胞敏感化作用的研究
Jung Mi Yun,Kyoung-Jin Min,Taeg Kyu Kwon
Jung Mi Yun
Background: Hispolon has been shown to possess antitumor effects in various cancer cells. However, the underlying mechanisms are not fully understood. In this study, we evaluated the sensitizing effect of hispolon on TNF-...
Effect of the Interaction Between Selenium and Zinc on DNA Repair in Association With Cancer Prevention [0.03%]
硒和锌的互作效应在癌症预防中的DNA修复作用研究进展
Aysegul Yildiz,Yesim Kaya,Ozgur Tanriverdi
Aysegul Yildiz
Cancer is the most common cause of death worldwide. Annually, more than ten million new cancer cases are diagnosed, and more than six million deaths occur due to cancer. Nonetheless, over 80% of human cancer may be preventable through prope...