Nanoparticles: Weighing the Pros and Cons from an Eco-genotoxicological Perspective [0.03%]
纳米颗粒：从生态-遗传毒理学角度权衡利弊
Preeyaporn Koedrith,Md Mujibur Rahman,Yu Jin Jang et al.
Preeyaporn Koedrith et al.
The exponential growth of nanotechnology and the industrial production have raised concerns over its impact on human and environmental health and safety (EHS). Although there has been substantial progress in the assessment of pristine nanop...
Meeting Report: Translational Advances in Cancer Prevention Agent Development Meeting [0.03%]
癌症预防剂开发转化进展会议报告
Mark Steven Miller,Peter J Allen,Powel H Brown et al.
Mark Steven Miller et al.
The Division of Cancer Prevention of the National Cancer Institute (NCI) and the Office of Disease Prevention of the National Institutes of Health co-sponsored the Translational Advances in Cancer Prevention Agent Development Meeting on Aug...
Ascorbic Acid Suppresses House Dust Mite-Induced Expression of Interleukin-8 in Human Respiratory Epithelial Cells [0.03%]
抗坏血酸抑制屋尘螨诱导的人呼吸道上皮细胞中白介素-8的表达
An Jun Lee,Joo Weon Lim,Hyeyoung Kim
An Jun Lee
House dust mite (HDM) is one of the significant causes for airway inflammation such as asthma. It induces oxidative stress and an inflammatory response in the lungs through the release of chemokines such as interleukin-8 (IL-8). Reactive ox...
Heregulin-β1 Activates NF-E2-related Factor 2 and Induces Manganese Superoxide Dismutase Expression in Human Breast Cancer Cells via Protein Kinase B and Extracellular Signal-regulated Protein Kinase Signaling Pathways [0.03%]
这里格林-β1通过蛋白质激酶B和细胞外信号调节蛋白激酶信号途径激活NF-E2相关因子2并诱导人乳腺癌细胞中锰超氧化物歧化酶的表达
Ji-Young Park,Soma Saeidi,Eun-Hee Kim et al.
Ji-Young Park et al.
Heregulin-β1, a ligand of ErbB-2 and ErbB-3/4 receptors, has been reported to potentiate oncogenicity and metastatic potential of breast cancer cells. In the present work, treatment of human mammary cancer (MCF-7) cells with heregulin-β1 ...
Nuclear Factor Erythroid 2-related Factor 2 Knockout Suppresses the Development of Aggressive Colorectal Cancer Formation Induced by Azoxymethane/Dextran Sulfate Sodium-Treatment in Female Mice [0.03%]
核因子 erythroid 2 相关因子 2 基因敲除抑制 azoxymethane/dextran 硫酸钠处理诱导的雌性小鼠侵袭性结直肠癌发生发展
Chin-Hee Song,Nayoung Kim,Ryoung Hee Nam et al.
Chin-Hee Song et al.
Colon tumors develop more frequently in male than in female. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays differential roles in the stage of tumorigenesis. The purpose of this study was to investigate the role of Nrf2 on colitis...
Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in Apc Min/+ Mice: Relation to Metabolism and Gut Microbiota Composition [0.03%]
游离脂肪酸受体2失调通过代谢和肠道菌群促进ApcMin/+小鼠结肠腺瘤形成
Yi-Wen Huang,Chien-Wei Lin,Pan Pan et al.
Yi-Wen Huang et al.
Free fatty acid receptor 2 (FFAR2) has been reported as a tumor suppressor in colon cancer development. The current study investigated the effects of FFAR2 signaling on energy metabolism and gut microbiota profiling in a colorectal cancer m...
Promotion of Cervical Screening among Long-term Non-attendees by Human Papillomavirus Self-sampling [0.03%]
人乳头瘤病毒自我取样促进长期未接受筛查者的宫颈癌筛查
Avalon Ernstson,Ola Forslund,Christer Borgfeldt
Avalon Ernstson
Cervical cancer is preventable through gynecological screening. To promote participation among non-attending women, self-collected vaginal samples for detection of high-risk human papillomavirus (hr-HPV) is an option. The aims of this study...
Understanding the Mechanistic Link between Bisphenol A and Cancer Stem Cells: A Cancer Prevention Perspective [0.03%]
理解双酚A与癌症干细胞之间的机制联系：从癌症预防的角度看
Cassandra Winz,Nanjoo Suh
Cassandra Winz
Endocrine disruptors, such as bisphenol A (BPA), have become more frequently present in the environment as contaminants, especially in industrialized countries. Long-term effects of these environmental contaminants in humans are elusive. Wi...
Beetroot as a Potential Functional Food for Cancer Chemoprevention, a Narrative Review [0.03%]
萝卜根作为癌症化学预防的潜在功能性食品：叙述性综述
Mei Lan Tan,Shahrul Bariyah Sahul Hamid
Mei Lan Tan
Patients with cancer are prone to several debilitating side effects including fatigue, insomnia, depression and cognitive disturbances. Beetroot (Beta vulgaris L.) as a health promoting functional food may be potentially beneficial in cance...
Imatinib and GNF-5 Exhibit an Inhibitory Effect on Growth of Hepatocellar Carcinoma Cells by Downregulating S-phase Kinase-associated Protein 2 [0.03%]
酪氨酸激酶抑制剂依马替尼和GNF-5通过下调S期激酶相关蛋白2抑制肝细胞癌生长的作用研究
Haibo Zhang,Junkoo Yi,Duhak Yoon et al.
Haibo Zhang et al.
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is one of the leading causes of cancer-related deaths worldwide. Imatinib and GNF-5 are breakpoint cluster region-Abelson murine leukemia tyrosine kinase inhibitors ...