Genetic Alterations and Microenvironment that Drive Malignant Progression of Colorectal Cancer: Lessons from Mouse and Organoid Models [0.03%]
驱动结直肠癌恶性发展的遗传变异和微环境：来自小鼠模型和类器官的启示
Mizuho Nakayama,Dong Wang,Sau Yee Kok et al.
Mizuho Nakayama et al.
Comprehensive genome analyses have identified frequently mutated genes in human colorectal cancers (CRC). These include APC, KRAS, SMAD4, TP53, and FBXW7. The biological functions of the respective gene products in cell proliferation and ho...
Involvement of AMP-activated Protein Kinase α/Nuclear Factor (Erythroid-derived 2) Like 2-iniatived Signaling Pathway in Cytoprotective Effects of Wasabi 6-(Methylsulfinyl) Hexyl Isothiocyanate [0.03%]
高良姜素通过活化AMPKα/ Nrf2信号通路发挥细胞保护作用的机制研究
Xuchi Pan,Kun Xie,Keyu Chen et al.
Xuchi Pan et al.
6-(Methylsulfinyl) hexyl isothiocyanate (6-MSITC) is an active ingredient present in Wasabi, which is a popular pungent spice used in Japanese cuisine. Our previous studies suggested that the primary antioxidant activity of 6-MSITC may link...
Nuclear Localization of Fibroblast Growth Factor Receptor 1 in Breast Cancer Cells Interacting with Cancer Associated Fibroblasts [0.03%]
乳腺癌细胞与癌相关成纤维细胞相互作用中的成纤维细胞生长因子受体1核定位
Jinyoung Suh,Do-Hee Kim,Su-Jung Kim et al.
Jinyoung Suh et al.
Cancer-associated fibroblasts (CAFs) represent a major component of the tumor microenvironment and interplay with cancer cells by secreting cytokines, growth factors and extracellular matrix proteins. When estrogen receptor-negative breast ...
Achanta Sri Venakata Jagadeesh,Xizhu Fang,Seong Hoon Kim et al.
Achanta Sri Venakata Jagadeesh et al.
Heme oxygenase-1 (HO-1) is a critical stress-responsive enzyme that has antioxidant and anti-inflammatory functions. HO-1 catalyzes heme degradation, which gives rise to the formation of carbon monoxide (CO), biliverdin, and iron. The upreg...
Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats [0.03%]
Diallyl trisulfide给药对化学诱导的大鼠乳腺肿瘤基因表达变化的影响研究
Eun-Ryeong Hahm,Shivendra V Singh
Eun-Ryeong Hahm
Diallyl trisulfide (DATS) was shown to be a potent inhibitor of luminal-type MCF-7 xenograft growth in vivo. The present study was conducted to determine the preventive effect of DATS administration using an N-methyl-N-nitrosourea (MNU)-ind...
Erratum: Dioscin Decreases Breast Cancer Stem-like Cell Proliferation via Cell Cycle Arrest by Modulating p38 Mitogen-activated Protein Kinase and AKT/mTOR Signaling Pathways [0.03%]
补遗：贝母皂苷通过调节p38丝裂原活化蛋白激酶和AKT/mTOR信号通路来减少乳腺癌干细胞样细胞的增殖
Chae Won Ock,Gi Dae Kim
Chae Won Ock
[This corrects the article on p. 183 in vol. 26, PMID: 34703821.]. Copyright © 2021 Korean Society of Cancer Prevention.
Published Erratum
Journal of cancer prevention. 2021 Dec 30;26(4):318. DOI:10.15430/JCP.2021.26.4.318 2021
Translational Advances in Cancer Prevention Agent Development (TACPAD) Virtual Workshop on Immunomodulatory Agents: Report [0.03%]
癌症预防剂开发(转移性癌症预防剂开发中免疫调节剂虚拟研讨会报道)
Altaf Mohammed,Roderick H Dashwood,Sally Dickinson et al.
Altaf Mohammed et al.
The National Cancer Institute (NCI) Division of Cancer Prevention (DCP) convened the "Translational Advances in Cancer Prevention Agent Development (TACPAD) Workshop on Immunomodulatory Agents" as a virtual 2-day workshop on September 13 to...
Epithelial Cell-specific Deletion of Microsomal Prostaglandin E Synthase-1 Does Not Influence Colon Tumor Development in Mice [0.03%]
小鼠上皮细胞特异性微粒体前列腺素E合成酶-1缺失不影响结肠肿瘤发生
Masako Nakanishi,Daniel W Rosenberg
Masako Nakanishi
Activation of the COX-2/microsomal prostaglandin E synthase-1 (mPGES-1)/prostaglandin E2 (PGE2) signaling axis is a hallmark of many cancers, including colorectal cancer, prompting the implementation of prevention strategies targeting COX-2...
Primary Care Provider Knowledge and Practice in Risk Assessment for Early Age Onset Colorectal Cancer: Opportunities for Improvement [0.03%]
关于早发性结直肠癌风险评估的初级保健提供者知识和实践：改进的机会
Anjali Parekh,Camille J Hochheimer,Jeannine M Espinoza et al.
Anjali Parekh et al.
Colorectal cancer (CRC) incidence and mortality are rising in individuals under age 50, termed early age onset (EAO) CRC. Lower endoscopy is recommended for all patients with unexplained iron deficiency anemia (IDA) or hematochezia to asses...
Steamed Ginger Extract Exerts Anti-inflammatory Effects in Helicobacter pylori-infected Gastric Epithelial Cells through Inhibition of NF-κB [0.03%]
姜蒸汽提取物通过抑制NF-κB在幽门螺旋杆菌感染的胃粘膜细胞中发挥抗炎作用
Moon-Young Song,Da-Young Lee,Sang-Yong Park et al.
Moon-Young Song et al.
Ginger (Zingiber officinale) has traditionally been used as a treatment for inflammatory diseases in the Asian region. Recently, anti-inflammatory effects of steamed ginger extract (GGE03) have been reported, but its association with Helico...