Exploring CD79b, LC3, and TERT expression in NON-GCB DLBCL: markers associated with Rituximab-Cyclophosphamide-Doxorubicin-Vincristin-Prednisone treatment response [0.03%]
Bethy S Hernowo,Arnita Ilanur,Hasrayati Agustina et al.
Bethy S Hernowo et al.
Introduction: Diffuse large B-cell lymphoma (DLBCL) represents the most common subtype of non-Hodgkin lymphoma. The non-germinal center B-cell-like (non-GCB) subtype is associated with a poor prognosis and reduced respons...
Enlarged splenic volume predicts poor survival and is associated with inflammatory imbalance in patients with diffuse large B-cell lymphoma [0.03%]
Zongjian Qiu,Rifeng Jiang,Shunquan Wu et al.
Zongjian Qiu et al.
Purpose: The spleen plays a significant role in innate and adaptive immunity. We aimed to evaluate the prognostic significance of the splenic volume in patients with diffuse large B-cell lymphoma (DLBCL), research on whic...
Deregulation of stemness and senescence genes in bone marrow mesenchymal stem cells of multiple myeloma: implications for therapeutic approaches [0.03%]
Fatemeh Soleymani,Saeideh Kavousi,Nastaran Khodakarim et al.
Fatemeh Soleymani et al.
Purpose: Multiple myeloma (MM) is a hematologic malignancy associated with a poor prognosis. MM-derived mesenchymal stromal cells (MM-MSCs) contribute to disease progression by creating a supportive stromal microenvironme...
Checkpoint inhibitor-induced hematologic immune-related adverse events and their association with disease recurrence in hematolymphoid malignancies: a clinical perspective [0.03%]
免疫检查点抑制剂诱导的血液系统免疫相关不良事件及其与血液淋巴系统恶性肿瘤疾病复发的关系：临床视角
Chokri Ben Lamine,Amr Hanbali,Ghada ElGohary et al.
Chokri Ben Lamine et al.
Immune checkpoint inhibitors have transformed the treatment of hematolymphoid malignancies by enhancing antitumor immunity. These agents are associated with immune-related adverse events (irAEs), including hematologic toxicities such as aut...
Monitoring of JAK2V617F allele burden in patients with essential thrombocythemia [0.03%]
必要血小板增多症患者JAK2V617F等位基因负担的监测
Jeong Suk Koh,Wonhyoung Seo,Sora Kang et al.
Jeong Suk Koh et al.
Background/aim: This study retrospectively examined the clinical implications of monitoring JAK2V617F, with a particular focus on disease transformation, in a Korean population of patients with essential thrombocythemia (...
Prognostic significance of PNH clones in aplastic anemia treated with immunosuppression or allogeneic HSCT: a 20-year single-center experience [0.03%]
免疫抑制或同种异基因造血干细胞移植治疗获得性再生障碍性贫血合并阵发性睡眠性血红蛋白尿意义的影响：单中心20年经验总结
Alfadil Haroon,Hazzaa Alzahrani,Mostafa F Mohammed Saleh et al.
Alfadil Haroon et al.
Background: Paroxysmal nocturnal hemoglobinuria (PNH) clones are detected in up to 60% of patients with aplastic anemia (AA); however, their prognostic impact remains incompletely defined, particularly in the context of f...
Targeting the HERV-K102 envelope elicits pyroptosis and represents a novel therapeutic strategy for acute myeloid leukemia [0.03%]
靶向HERV-K102包膜可引发细胞炎性焦亡，或可作为急性髓系白血病的新型治疗策略
Lihong Zong,Qian Luo,Jingru Zhao et al.
Lihong Zong et al.
Objective: Several recent studies have focused on human endogenous retroviruses (HERVs). HERVs entered the human genome millions of years ago and are associated with various diseases including cancer and immune regulation...
Autologous bone marrow transplantation in non-Hodgkin lymphoma patients following different conditioning regimens: an 11-year single-center quasi-experimental study [0.03%]
不同预处理方案下自体骨髓移植治疗非霍奇金淋巴瘤患者的疗效分析——一项为期11年的单中心类实验研究
Sahar Tavakoli Shiraji,Mohammad Biglari,Soroush Rad et al.
Sahar Tavakoli Shiraji et al.
Purpose: Non-Hodgkin lymphoma (NHL) constitutes 90% of all lymphomas and accounts for 2.8% of new cancer cases and 2.6% of cancer-related deaths in 2020. Hematopoietic stem cell transplantation remains the standard treatm...
Comparative evaluation of two NGS-based assays for somatic hypermutation analysis of IGHV genes in chronic lymphocytic leukemia [0.03%]
评估基于NGS的两种方法在慢性淋巴细胞白血病IGHV基因体细胞高突变分析中的比较效果
Yehyun Kang,Hyeonah Lee,Yu Jin Park et al.
Yehyun Kang et al.
Purpose: Somatic hypermutation (SHM) of the immunoglobulin heavy chain variable (IGHV) region is a key prognostic marker in chronic lymphocytic leukemia (CLL). Traditionally, SHM status has been determined using Sanger se...
Letermovir for cytomegalovirus prophylaxis in pediatric allogeneic hematopoietic stem cell transplantation: a single-center experience [0.03%]
儿童异基因造血干细胞移植中勒特莫韦预防巨细胞病毒感染的单中心研究经验
Pai-Lin Tsai,Meng-Yao Lu,Hsiu-Hao Chang et al.
Pai-Lin Tsai et al.
Purpose: Letermovir prophylaxis results in a significantly lower risk of clinically significant cytomegalovirus (CMV) infection in adult hematopoietic stem cell transplant recipients. However, studies supporting its effic...