Comparison of the proposed new classification of anal fistulas with the Garg classification [0.03%]
新分类肛瘘与Garg分类的比较研究
Pankaj Garg,Nicola Clemente,Kaushik Bhattacharya et al.
Pankaj Garg et al.
Mini-invasive J-colpo-perineo-rectopexy with titanized polypropylene mesh for global perineal descent: a technical note [0.03%]
带钛夹的聚丙烯网片行迷你腹腔镜全会阴固定提升手术（JCPR）的技术报告
Carlotta La Raja,Francesca Lecchi,Sandro Carnio et al.
Carlotta La Raja et al.
Effectiveness of primary tumor resection for survival after first-line cetuximab or bevacizumab in KRAS wild-type metastatic colorectal cancer treated with subsequent trifluridine/tipiracil or regorafenib [0.03%]
西妥昔单抗或贝伐单抗一线治疗后使用曲氟尿苷/替匹嘧啶或瑞戈非尼二线治疗的野生型KRAS转移性结直肠癌患者中，原发肿瘤切除对生存的影响
Yu-Hsun Chen,Chih-Chien Wu,Chien-Chou Su et al.
Yu-Hsun Chen et al.
Purpose: The optimal sequencing of targeted therapies and the role of primary tumor resection (PTR) in KRAS wild-type metastatic colorectal cancer (mCRC) remain unclear. This study compared survival outcomes in patients t...
Upfront surgery versus preoperative chemoradiotherapy: a comparative survival analysis for stage II/III resectable rectal cancer [0.03%]
前期手术与术前放化疗的生存对比研究——局部进展期直肠癌患者的治疗选择
Nattapanee Sukphol,Thitithep Limvorapitak
Nattapanee Sukphol
Purpose: Current international guidelines recommend neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision (TME) for locally advanced rectal cancer (LARC). Although nCRT reduces the risk of local recur...
Comparative outcomes of early and late rectourethral fistula: insights from a multicentric retrospective study on multidisciplinary management strategies [0.03%]
早期与晚期直肠-尿道瘘 comparative outcomes of early and late rectourethral fistula：多中心回顾性研究带来的多学科管理策略见解
Pauline Jeannot,Edouard Roussel,Alexandre Dutoit et al.
Pauline Jeannot et al.
Purpose: The objective of this study was to evaluate the natural history of early and late rectourethral fistulas (RUFs) and to determine the long-term outcomes of a multidisciplinary management approach. ...
Survival impact of radiotherapy for patients with de novo metastatic rectal cancer [0.03%]
初始发生转移的直肠癌患者放疗的影响及作用
Harvey Yu-Li Su,Yun-Hsuan Lin,Ko-Chao Lee et al.
Harvey Yu-Li Su et al.
Purpose: Metastatic rectal cancer (mRC) is a highly lethal and complex disease that demands a multidisciplinary treatment approach. However, the clinical effectiveness of radiotherapy (RT) for de novo mRC remains controve...
Interim analysis of short-term outcomes between robotic and laparoscopic surgery for colon cancer: results from the ESSIMIC trial [0.03%]
中期分析：机器人结肠癌手术与腹腔镜结肠癌手术短期结局的比较：ESSIMIC试验结果
Marco Milone,Sara Vertaldi,Pietro Anoldo et al.
Marco Milone et al.
Purpose: This study aimed to determine whether the benefits of robotic surgery can be applied to the treatment of colon cancer by evaluating short-term outcomes of robotic versus laparoscopic colonic resection. ...
Gut microbiome in colorectal cancer: recent advances and clinical implications [0.03%]
肠道微生物群与结直肠癌：最新研究进展及其临床意义
Jun Yong Han,Min Jung Kim,Ji Won Park et al.
Jun Yong Han et al.
The gut microbiome is not just a bystander of colorectal carcinogenesis but is an active driver of colorectal cancer (CRC). CRC-associated microbiome contributes in the tumorigenesis through chronic inflammation, formation of toxic metaboli...
Fluorescence-guided surgery in colorectal cancer: current evidence, quantitative advances, and future perspectives [0.03%]
结直肠癌的荧光引导手术：当前证据、定量进展和未来展望
Kyung-Ha Lee
Kyung-Ha Lee
Fluorescence-guided surgery (FGS) has progressed from a qualitative adjunct to a quantitative, data-driven tool in colorectal surgery. Fluorescence-guided angiography for perfusion assessment shows mixed randomized results overall, with sig...
Immunotherapy for microsatellite-stable colorectal cancer: overcoming resistance and exploring novel therapeutic strategies [0.03%]
微卫星稳定型结直肠癌的免疫治疗：克服耐药性及探索新型治疗策略
Sun Young Kim
Sun Young Kim
Microsatellite-stable (MSS) colorectal cancer (CRC), comprising 85% to 95% of all CRC cases, represents a significant therapeutic challenge in the era of cancer immunotherapy. Unlike microsatellite instability-high tumors that demonstrate r...