Mitigation of artifacts in imaging biosamples with optical scanning transmission electron microscopy [0.03%]
基于光学扫描透射电子显微镜的光学成像生物样本的去伪影方法研究
Arent J Kievits,B H Peter Duinkerken,Ryan Lane et al.
Arent J Kievits et al.
Electron microscopy (EM) allows ultrastructural analysis of biological tissues and cells, but images frequently contain artifacts because biological samples have to undergo rigorous preparation to be resistant to vacuum conditions and elect...
Seonhye Son,Sujin Lee,Jihyun Kim et al.
Seonhye Son et al.
Cryo-electron tomography (cryo-ET) has become a key technique for observing the three-dimensional structures of biomolecular complexes and organelles in cellular and tissue environments in situ. However, for thicker specimens that cannot be...
Cationic lipid-based nanoparticles for therapeutic delivery in cancer treatment: physicochemical characteristics, therapeutic cargos, and clinical potential [0.03%]
阳离子脂质基纳米颗粒在癌症治疗中的治疗递送：物理化学性质、治疗药物和临床潜力
Chun-Sik Bae,Taeho Ahn
Chun-Sik Bae
Over the past few decades, numerous biological therapeutics, such as RNAs and polypeptides, have emerged as promising alternatives to traditional chemotherapy. While their molecular mechanisms of action are well-understood, their clinical a...
Saif Haider Kayani,Sang-Ik Lee,Yoon-Ho Lee et al.
Saif Haider Kayani et al.
The strength of precipitation-hardened Al–Si–Mg alloys primarily derives from the nanoscale coherent β″ precipitates, which are the dominant contributors to strengthening under peak-aged conditions. Observing these nanoscale precipitate...
Viability classification of unstained cells in microscopic images using deep learning [0.03%]
基于深度学习的显微图像中未经染色细胞活力分类
Tomoaki Kyoden,Shunsuke Akiguchi,Ryo Murakami et al.
Tomoaki Kyoden et al.
In research on cells conducted in vitro, cell viability is determined using staining techniques. However, interference with subsequent observation of live cell growth limits their applicability for real-time or continuous investigation. To ...
Etching methods for revealing nanoscale precipitates and carbides in Ni-based superalloys [0.03%]
镍基高温合金中纳米级沉淀相和碳化物的刻蚀方法研究
Seung Gyu Hong,Cho Hyeon Lee,Seong Hyeon Yang et al.
Seung Gyu Hong et al.
Gamma prime (γ') precipitates and grain boundary (GB) carbides govern the high-temperature performance of Ni-based superalloys, and their reliable quantification is essential for microstructural evaluation and alloy development. However, c...
Fractography of white charcoal reveals past fungal infection and embolism in the secondary xylem via SEM [0.03%]
扫描电镜揭示白炭的木质部曾遭受真菌感染及栓塞的断裂学研究
Chul Jong Yoon,Ki Woo Kim
Chul Jong Yoon
The internal structures of fractured white charcoal were investigated using a scanning electron microscope. The charcoal was fractured using a razor blade and hammer, gold-coated, and observed under the electron microscope. Both embolized a...
Advances in EBSD-based approaches for quantifying slip activity in deformed Mg alloys [0.03%]
基于EBSD的定量变形镁合金滑移活性的方法学进展
Hafiz Muhammad Rehan Tariq,Tea-Sung Jun
Hafiz Muhammad Rehan Tariq
Plastic deformation in Mg alloys requires a full understanding of slip activity and intergranular interactions, which determine mechanical behavior and strain localization. Electron backscatter diffraction (EBSD) has emerged as a versatile ...
Antonie van Leeuwenhoek and the dawn of microscopic observation: a narrative review from Delft's lens to the modern microscope [0.03%]
列文虎克与微观观察的黎明：从代尔夫特透镜到现代显微镜的故事性回顾
Hyunjeong Lee,Im Joo Rhyu
Hyunjeong Lee
Antonie van Leeuwenhoek (1632-1723) transformed observation into science through the power of a single handmade lens. His work emerged from the visual culture of seventeenth-century Delft, where craftsmanship, optics, and artistic precision...
The effects of nanopillar and nanopit arrays on the morphology and osteogenic differentiation of adipose-derived stem cells [0.03%]
纳米柱和纳米坑阵列对脂肪源干细胞形态及成骨分化的影响
Jihun Kang,Young-Shik Yun,Eun-Hye Kang et al.
Jihun Kang et al.
Nanotopographic control of cell behavior offers great potential in designing biomimetic scaffolds for cell therapy. However, the behavior of cells on different nanotopographies is not fully understood. In this study, we investigated the eff...