Immunotherapy-Based Strategies versus Transcatheter Arterial Chemoembolization and the Impact of Treatment Duration in Hepatocellular Carcinoma with Microvascular Invasion: A Retrospective Multicenter Cohort Study [0.03%]
基于免疫治疗的策略与肝动脉化疗栓塞在微血管侵犯性肝细胞癌中的影响：一项回顾性多中心队列研究
Xiaokun Chen,Jiali Xing,Baoluhe Zhang et al.
Xiaokun Chen et al.
Background: Hepatocellular carcinoma (HCC) with microvascular invasion (MVI) is associated with high recurrence risk after curative resection. While adjuvant immune checkpoint inhibitors (ICIs) have shown potential in imp...
P-ART Score is a New Modification to Improve ART Score Predictive Accuracy for Patients with HCC Undergoing TACE [0.03%]
改良的ART评分（P-ART评分）可提高预测接受TACE治疗的肝癌患者疗效的准确性
Ahmed Attia,Esam Ali Elshimi,Zeinab Mohamed Seif Eldin et al.
Ahmed Attia et al.
Background: Predicting the prognosis of patients with HCC is challenging. Aim: To evaluate the Assessment for Retreatment with TACE (AR...
Early PIVKA-II Response Predicts Treatment Efficacy of Immune Checkpoint Inhibitors in Patients with Advanced Hepatocellular Carcinoma [0.03%]
治疗前和治疗早期PIVKA-II变化对免疫检查点抑制剂治疗晚期肝细胞癌疗效的预测价值
Ching-Tso Chen,Chien-Huai Chuang,Chih-Hung Hsu et al.
Ching-Tso Chen et al.
Background and aims: Early alpha-fetoprotein (AFP) response has been reported to predict the treatment efficacy of immune checkpoint inhibitors (ICIs) in patients with advanced hepatocellular carcinoma (HCC). We evaluated...
Prognostic Signature of NETs-Related Genes in Hepatocellular Carcinoma Based on Bulk and Single-Cell Transcriptomics [0.03%]
基于Bulk和单细胞转录组的肝癌NETs相关基因预后标志物研究
Ningning Lu,Zhixia Gu,Xiaoxue Yuan et al.
Ningning Lu et al.
Background: Inflammation drives tumor development, with neutrophil extracellular traps (NETs) promoting progression through metastasis, immune suppression, and microenvironment modulation. However, the role of NETs-relate...
Prediction Model for Risk of Hepatocellular Carcinoma After Hepatitis C Viral Eradication [0.03%]
预测丙型肝炎病毒根除后发生肝细胞癌风险的模型
Wei-Fan Hsu,Ching-Chu Lo,Kuo-Chih Tseng et al.
Wei-Fan Hsu et al.
Purpose: The predictors of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C (CHC) and a sustained virologic response after direct-acting antiviral therapy are not well known. ...
Hypoxia- and Anoikis-Related lncRNA Signature Defines Molecular Subtypes and Predicts Prognosis and Immunotherapy Response in Hepatocellular Carcinoma [0.03%]
缺氧和悬吊诱导相关长链非编码RNA特征定义肝细胞癌分子亚型并预测预后及免疫治疗反应
Xiaohang Lu,Yunyong Wang,Yuan Yu et al.
Xiaohang Lu et al.
Background: Hepatocellular carcinoma (HCC) is characterized by high incidence and mortality rates, with hypoxia and anoikis resistance playing crucial roles in its progression and metastasis. While long non-coding RNA (ln...
Impact of Cytokeratin 19 Expression on the Outcomes of Unresectable Hepatocellular Carcinoma Treated with Targeted Therapy and Immunotherapy: A Propensity Score Matched Analysis [0.03%]
细胞角蛋白19表达对不可切除肝细胞癌靶向及免疫治疗结局影响的倾向性匹配分析
Junjie Liu,Tong Yuan,Xing Lv et al.
Junjie Liu et al.
Background: Cytokeratin 19 (CK19) serves as a significant prognostic indicator for hepatocellular carcinoma (HCC). However, it is uncertain if CK19 expression influences the prognosis and effectiveness of treatment in pat...
Prognostic Value of Clinical and CT Features in Camrelizumab Plus Apatinib Treatment for Unresectable Hepatocellular Carcinoma [0.03%]
卡瑞利珠单抗联合阿帕替尼治疗不可切除肝细胞癌的临床及CT特征预后价值
Jinlian Che,Yidi Chen,Zhiming Zeng et al.
Jinlian Che et al.
Background: Immunotherapy combined with targeted therapy is a key approach for patients with unresectable hepatocellular carcinoma (HCC). This study aimed to evaluate the prognostic value of clinical and CT features in Ca...
MRI-Based Deep Learning and Radiomics Nomogram for Predicting Hepatocellular Carcinoma Recurrence Within Six Months After Thermal Ablation [0.03%]
基于MRI的深度学习和影像组学预测热消融后六个月内肝癌复发的风险 nomogram模型构建及验证
Yao Chen,Yanan Zhao,Weiwei Guan et al.
Yao Chen et al.
Purpose: Develop a magnetic resonance imaging (MRI)-based deep learning (DL)-radiomics (Rad)-clinical nomogram for predicting early recurrence of hepatocellular carcinoma (HCC) within six months after thermal ablation. ...
Establishing a Survival Time Prediction Model for Patients with Hepatocellular Carcinoma After TACE Based on CT Radiomics: A Multi-Center Study [0.03%]
基于CT影像组学的肝细胞癌患者经导管动脉化疗栓塞治疗后生存时间预测模型的建立：一项多中心研究
Han Yang,Juan Zhao,Yingwei Wang et al.
Han Yang et al.
Purpose: This research constructs a prognostic model for overall survival (OS) in hepatocellular carcinoma (HCC) patients using radiomic features from non-contrast CT scans obtained within 24 hours after transarterial che...