Neutrophil Extracellular Traps in Sepsis and Sepsis-Related Organ Dysfunction [0.03%]
脓毒症和脓毒症相关器官功能障碍中的中性粒细胞胞外陷阱
Wenbo Yan,Xiyuan Xu,Xiaojuan Li et al.
Wenbo Yan et al.
Sepsis is a systemic inflammatory response triggered by infection, which can result in multiple organ dysfunctions, including disseminated intravascular coagulation (DIC) and acute lung injury (ALI), ultimately leading to patient mortality....
The Role of Intestinal Microbiota and Immune System Interactions in Autoimmune Diseases [0.03%]
肠菌与免疫系统相互作用在自身免疫病中的作用
Batuhan Yurtseven,Esra Aydemir,Furkan Ayaz
Batuhan Yurtseven
Background: The intricate interplay between the intestinal microbiota and the immune system has emerged as a central theme in understanding autoimmune disease pathogenesis. This review comprehensively explores the role of...
Deep Learning Classification of Rheumatoid Arthritis in Hand Radiographs Interpretability Insights and Web Application [0.03%]
基于深度学习的类风湿性关节炎手部X光片分类：可解释性的见解与网络应用开发
Kanglin Cai,Dengfeng Dou,Guibing Deng et al.
Kanglin Cai et al.
Purpose: To establish an interpretable deep learning framework for automated classification of rheumatoid arthritis (RA) in hand radiographs, with emphasis on elucidating model decision-making patterns and enabling clinic...
Multi-Dimensional Characterization of Programmed Cell Death Patterns for Prognostic Stratification and Therapeutic Insights in Sepsis [0.03%]
脓毒症预后分层和治疗启示的程序性细胞死亡模式的多维特征刻画
Chen Zhou,Yunmeng Bai
Chen Zhou
Background: Sepsis is a complex and heterogeneous syndrome characterized by dysregulated immune responses and multiple forms of programmed cell death (PCD). Comprehensive understanding of the PCD landscape may provide ins...
Clinical Risk Stratification and Modifiable Risk Factors for Hepatitis B Virus-Related Follicular Lymphoma [0.03%]
乙型肝炎病毒相关滤泡性淋巴瘤的临床风险分层及可改变危险因素
Yuwei Deng,Zhenyuan Jia,Huilai Zhang et al.
Yuwei Deng et al.
Background: Hepatitis B virus (HBV) infection (surface antigen positive, HBsAg+) has been related to the increased risk in follicular lymphoma (FL). The further understanding of features in HBV-associated FL remains lacki...
Emerging Role of MDSCS as Novel Biomarkers and Therapeutic Targets for Cancer Immunotherapy [0.03%]
MDSCs作为癌症免疫治疗中新生物标志物和治疗靶点的作用机制及其临床意义
S Silva-Romeiro,Rocio Del Carmen Flores-Campos,María Luisa Sánchez-León et al.
S Silva-Romeiro et al.
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that accumulate under pathological conditions such as cancer, where they contribute to immune evasion, tumor progression, and resistance to th...
Zeynep Meric,Muhammed Aydin,Dilan Demir Gumus et al.
Zeynep Meric et al.
Hyper-IgE syndromes represent an increasingly recognized and heterogeneous group of disorders characterized phenotypically by eczema, recurrent infections, and markedly elevated serum IgE levels. The identification of novel molecular defect...
Profiling Shared Cytotoxic Immune Signatures in SLE-Associated Coronary Injury Through Transcriptomics and Machine Learning [0.03%]
通过转录组学和机器学习剖析SLE相关冠状损伤的共享细胞毒性免疫特征
Yongkang Chen,Shuk Ming Tso,Feng Wu et al.
Yongkang Chen et al.
Purpose: This study investigated shared molecular pathways linking systemic lupus erythematosus (SLE) and coronary artery disease (CAD) to uncover mechanisms of coronary injury in SLE. ...
Soluble Programmed Cell Death-1: A Potential Predictor of HBsAg Loss in Pediatric Patients with Chronic Hepatitis B Undergoing Peginterferon Therapy [0.03%]
可溶性程序性死亡配体1预测慢性乙型肝炎患儿干扰素治疗效果的作用
Guifeng Yang,Yifan Gan,Muye Xia et al.
Guifeng Yang et al.
Purpose: Soluble programmed cell death-1 (sPD-1) level can predict hepatitis B surface antigen (HBsAg) loss in adult chronic hepatitis B (CHB) patients. However, whether sPD-1 level can serve as a potential seromarker for...
Glucose Metabolic Reprogramming of Macrophages Against Mycobacterium tuberculosis Infection [0.03%]
结核分枝杆菌感染下巨噬细胞糖代谢重编程研究进展
Tianhui Liu,Zeliang Yang,Jing Tong et al.
Tianhui Liu et al.
Tuberculosis (TB) is a global infectious disease caused by Mycobacterium tuberculosis (Mtb). Serving as the primary effector cells, macrophages play a crucial role in host immune responses against Mtb. During Mtb infection, macrophages unde...