Mesenchymal stem cell-conditioned media alleviates diabetic cardiomyopathy by modulating glycemic control, oxidative stress-induced injury and inflammation regulation [0.03%]
间充质干细胞诱导培养液通过调节血糖控制、氧化应激损伤和炎症反应来缓解糖尿病心肌病
Abeer M Abd El-Hameed,Fatimah A R AbdulAlim,Hebatullah A Abdulgawad
Abeer M Abd El-Hameed
A major consequence of diabetes mellitus (DM) is a diabetic cardiomyopathy (DC). It is a clinical confusion that is identified when individuals with DM develop ventricular dysfunction without having coronary artery disease, heart disease or...
Anti-diabetic drugs: a novel therapeutic approach against cisplatin-induced kidney injury, a mechanistic review of preclinical studies [0.03%]
抗糖尿病药物：顺铂诱导的肾损伤的新型治疗方法，一项机制性的综述性研究
Amirhossein Niknejad,Yasamin Hosseini,Dietrich Büsselberg et al.
Amirhossein Niknejad et al.
Cisplatin (Cis) is a potent anti-cancer agent with limited clinical application due to severe adverse effects, including nephrotoxicity. Acute kidney injury (AKI) is the most frequently observed type of nephrotoxicity following Cis administ...
Enteroendocrine hormones and gut microbiota in obesity: a systematic review from mechanistic insight to precision metabolic care [0.03%]
肠嗜铬细胞激素和肥胖患者肠道菌群：从精准代谢照护的机制见解到系统性回顾
Navodi Sandamini Jayathilaka,Krishanthi Jayamini Wijekoon,Singappulige Dona Dilmi Sachinthani et al.
Navodi Sandamini Jayathilaka et al.
Purpose: This systematic review aims to synthesize current evidence on enteroendocrine cell alterations in obesity, elucidate the mechanisms by which gut microbial taxa and metabolites regulate gut hormone release, and as...
Sarah El Yaman,Kathryn Swaby,Jeffrey N Bernstein et al.
Sarah El Yaman et al.
Purpose: To report a case of polydrug ingestion involving levothyroxine and insulin in an adolescent, demonstrating potential protective effects of insulin co-ingestion against symptomatic thyrotoxicosis. ...
Functional renal stress and electrolyte shifts in type 2 diabetes: isolated urea elevation and a hypernatremic phenotype in an arid climate [0.03%]
2型糖尿病的肾功能应激和电解质转移：孤立性血尿素升高和高钠血症表型在干旱环境中的研究
Ahmed Zeyad Rahemmah,Hamid Choobineh,Fariba Nabatchian et al.
Ahmed Zeyad Rahemmah et al.
Background: Type 2 diabetes mellitus (T2D) disrupts fluid and electrolyte homeostasis through hyperglycemia-induced osmotic diuresis and insulin resistance, yet the interplay between electrolyte shifts, renal stress, and ...
Dysregulated indoleamine 2,3-dioxygenase contributes to metabolic syndrome [0.03%]
失调的色氨酸酶参与代谢综合征的发展
Marjan Khorsand,Farideh Eskandari,Mohammad Ali Takhshid
Marjan Khorsand
Purpose: Dysregulation of tryptophan (Trp) metabolism, specifically changes in Kynurenine (Kyn) and indoleamine 2,3-dioxygenase (IDO) activity, has been associated with the initiation of chronic inflammation, oxidative st...
A systematic review of randomized controlled trials assessing the efficacy of negative pressure wound therapy in diabetic foot wounds [0.03%]
糖尿病足溃疡负压治疗有效性的系统综述研究
Semra Usta,Emine Kaplan Serin
Semra Usta
Background: Negative Pressure Wound Therapy (NPWT) has emerged as a pivotal intervention for managing diabetic foot ulcers (DFUs), offering substantial benefits for enhancing wound-healing outcomes. ...
Association of Triglyceride-Glucose (TyG) index and carotid intima-media thickness in early adulthood: Tehran lipid and glucose study [0.03%]
Tehran Lipid and Glucose Study (TLGS)：青年期胰岛素抵抗标志物TyG指数与颈动脉内膜中层厚度的关系
Amirhosein Seyedhoseinpour,Maryam Barzin,Maryam Mahdavi et al.
Amirhosein Seyedhoseinpour et al.
Background: The association of the Triglyceride-glucose (TyG) index as a novel surrogate marker of IR with atherosclerotic CVD has been suggested previously. However, there is limited data available for young adults. We a...
Metabolic syndrome among Arab American adolescent-parent dyads: the influence of psychosocial stress [0.03%]
阿拉伯美洲青少年及其父母代谢综合征的影响：心理社会压力的作用
Maha M Albdour,Ali Darwiche,Elizabeth S Jenuwine et al.
Maha M Albdour et al.
Purpose: Psychosocial stress may explain metabolic health disparities observed among immigrants, including Arab Americans (AA). This study examined the psychosocial stressors, including parent-adolescent relationships, di...
The simplified method for quantifying metabolic syndrome (siMS) score reflects an increased cardiometabolic burden: adiposity, hemodynamics, and HRV findings in young adults [0.03%]
简化的代谢综合征量化方法(siMS评分)反映了增加的心血管代偿负担：年轻成年人中的肥胖、血液动力学和HRV指标发现
Christopher J Kotarsky,Jillian M Lang,Elena S Shostak et al.
Christopher J Kotarsky et al.
Purpose: Metabolic Syndrome (MetS) increases cardiovascular disease risk, yet early identification of pre-MetS remains challenging. The Simple Method for Quantifying MetS (siMS) score offers potential for detecting cardio...